Chloride Flashcards
Chloride is the most abundant anion in the ICF or ECF?
EXTRACELLULAR FLUID
Chloride has a negative or positive charge?
NEGATIVE charge
Its negative charge neutralizes the positive charge of sodium (which is important for electrolyte balance).
What is the best food source of chloride?
Nearly all of the chloride consumed in the diet is associated with sodium in table SALT
Abundant in processed foods
Found in eggs, fresh meats, seafood
What are the functions of chloride? **
- Major electrolyte
- Formation of HYDROCHLORIC ACID (DIGESTIVE SYSTEM)
- Secreted by WBCs during phagocytosis to assist in the destruction of foreign substances (IMMUNE SYTEM)
What are the functions of chloride? **
- Major electrolyte
- Formation of HYDROCHLORIC ACID (DIGESTIVE SYSTEM)
- Secreted by WBCs during phagocytosis to assist in the destruction of foreign substances (IMMUNE SYTEM)
- Exchange anion with HCO3 (bicarbonate); “Chloride shift” or “hamburger phenomenon.”
Explain the chloride shift **
Helps with the exchange of HCO3 from RBCs
Where RBCs have C02 and the CO2 will be converted to HCO3 (which is impermeable to the RBCs, it can’t exit the RBCs). So, CHLORIDE moves into the RBC, allowing HCO3 to move out. This is one-way to get rid of CO2 in the body.
How is chloride excreted?
Excretion occurs in:
GI tract (HCl acid)
SKIN
KIDNEYS/URINE ** major route
How is chloride excretion regulated?
It is regulated indirectly through sodium regulation
What is the AI of chloride?
2,300 mg (set by the FNB)
What is the RDA for chloride?
Not enough evidence to establish an RDA
What dietary factors influence blood pressure?
SODIUM
POTASSIUM
CALCIUM
MAGNESIUM
HTN affects how many Americans?
~33%
It increases the risk of stroke and heart disease
(TRUE/FALSE)
Reductions in sodium intake are associated with reductions in blood pressure.
TRUE
Recommend the DASH diet
What individuals are more salt sensitive?
Salt has a greater impact on BP
African Americans
Obese individuals
Individuals over 65 y/o (Elderly- hormonal systems are not working as well)
(TRUE/FALSE)
High K+ intake reduces BP.
TRUE
A meta-analysis showed that potassium supplementation was associated with significant reductions in BOTH systolic and diastolic BP.
Effects were more apparent in African Americans and in those with HTN, than in whites and those w/o HTN
