Chlamydial infections Flashcards
T/F Chlamydophila pneumoniae are obligate intracellular pathogens
T
Chlamydophila: Infectious form
Elementary body (EB)
Chlamydophila: Reproductive form
Reticulate body (RB)
T/F Ability to cause prolonged often subclinical infection is one of the major characteristics of chlamydiae
T
T/F Pneumonia caused by Chlamydophila is a classical atypical type with mild to moderate constitutional symptoms and CXR worse than clinical status of px
T
Optimum site for culture of C. pneumoniae
Posterior nasopharynx
Effective for eradication of C. pneumoinae from nasopharynx in ~80% of cases
Erythromycin, clarithromycin, azithromycin
Most important preventable cause of blindness in the world
Trachoma caused by chlamydia trachomatis
Criteria for trachoma
2 of 4: 1) Lymphoid follicles on upper tarsal conjunctivae 2) Typical conjunctival scarring 3) Vascular pannus 4) Limbal follicles
WHO recommends ___ for treatment of trachoma in children
Single-dose azithromycin
C. trachomatis is a major cause of what STDs
Epididymitis and nongonococcal urethritis
As many as ___% of men with gonorrhea may be co-infected with C. trachomatis
50
T/F Detection of C. trachomatis in vagina or rectum of a young child is an absolute evidence of sexual abuse
F, Perinatally acquired vaginal and rectal infection can persist for ≥3 years
Culture specimens for chlamydia detection
Urethral discharge in men and endocervical secretions in women
1st line treatment regimen recommended by CDC for uncomplicated C. trachomatis genital infection in men
Azith and Doxy
