Chlamydia, Rickettsia, And Friends

Question 1

Chlamydia Trachomatis (A, B, C)

Answer 1

Cause trachoma

Transmission is mechanical (finger to eye) or by flies

Chronic reinfect ion of conjucvtiva causes infolding of lashes and scarring of cornea

Question 2

Trachoma

Answer 2

Eye disease

LEADING cause of preventable blindness

Symptoms:

• cloudy cornea
• discharge
• swelling

Question 3

Treating/Preventing Trachoma

Answer 3

F
A
C
E

Question 4

C. Tra. (L1, L2, L3)

LVG

Answer 4

Venereal disease

Question 5

Rickettsia General

Answer 5

Intracellular parasite

Arthropoda = disease vector

Question 6

Rickettsia growth cycle

Answer 6

Actively promotes phagocytosis

Slow growth

Cell released

Question 7

Progression of Typhus

Answer 7

Infection

ten day incubation

Sudden fever and headache

Rash 4 days later

Fatal in children

Question 8

Transmission of R. Prowazekki

Answer 8

Human -> body louse -> human -> body louse

Louse punctures skin and poops in it (WHHYYYYY)

Scratching makes worse

Question 9

Prevention and Treatment of Typshus

Answer 9

Tetracyclines

Prevention = louse control

Question 10

Diagnosis typhus

Answer 10

PCR

Serological tests (compare over time)

Liver tests often elevated

Question 11

Brill Zinsser Disease

Answer 11

Latent infection of R. Prowazekii flares up

Similar to primary typhus (headache, rash, liver enzymes)

Same treatment

Question 12

Random Typhus

Answer 12

Can come from squirrels

Question 13

Rickettsia TYPHI

Answer 13

Closely related to Prowazekki
-milder than Pro

Transmitted by fleas (not louse)

Common in rodents

Question 14

Rickettsia RICKETTSII

Answer 14

Causes Rocky Mountain SPotted Fever

Fever, headache, arthritic pain, abdominal pain

Rash on hands and feet, spreading to trunk

Untreated mortality 20%

Question 15

R. RICKETTSII life cycle

Answer 15

Transovarian

Aka babies of infected ticks carry disease! Oh no,