Chlamydia

Question 1

Pneumoniae

Answer 1

Human 
Horse
Koala
Multisystem
Reptile
Amphibians

Question 2

Pecorum

Answer 2

Ruminants
Pigs
Koala
Multisystem

Question 3

Caviae

Answer 3

Guinea pig conjunctivitis/pneumonitis

Question 4

Psittaci

Answer 4

Avian resp disease

Zoonotic

Question 5

Abortus

Answer 5

Ruminant abortion

Zoonotic

Question 6

Felis

Answer 6

Cat conjunctivitis and rhinitis

Question 7

Trachomatis

Answer 7

Human ocular and urogenital

Question 8

Muridarum

Answer 8

Mouse resp and urogenital

Question 9

Suis

Answer 9

Porcine pneumonia
Enteritis
Conjunctivitis

Question 10

Chlamydia description

Answer 10

Obligate IC

G-ve

Question 11

Trachomatis genital tract infections incubation period and symptoms

Answer 11

Incubation 7-14d
Pain on discharge or urine can last a few days,
Many asymptomatic

Question 12

Genital chlamydia conseq

Answer 12

Persistance can cause immpath and irreversible tissue dam
Pelvic inflam disease and infertility
Ectopic pregnancy
Risk factor for persistant oncogenic HPV

Question 13

Genital chlamydia infection type and treatment

Answer 13

Persistent/chronic with re-infection common
Disease caused by immpath
Treated with antibio no vacc

Question 14

Elementary body

Answer 14

Infective stage
Spore like
Res to enviro stress
Can’t multiply

Question 15

Reticulate body

Answer 15

Non infective

Replication stage i. Host cell

Question 16

Chlamydia pathogenesis

Answer 16

EB
Adhere to CM
Endocytosis and remain in vacuole
Prev lysosome-phagosome fusion
EB to RB transformation
Division to form an inclusion
Differentiate to EB
Host cell lysis

Question 17

Trachomatis ocular infection

Answer 17

Leading cause of preventable blindness

Infection starts in childhood and is persistent

Question 18

Pneumoniae causes

Answer 18

Acute resp infections (horse koala human reptile amphibian)
Most mild but can be severe
Role in chronic inflam lung disease and putative links with coronary heart disease

Question 19

Mouse models

Answer 19

Muridarum model for human genital tract and lung infection

Caviae model for genital tract and maybe ocular infection

Question 20

Suis causes

Answer 20

Common pig infection assoc with asympt GI infection also conjunctivitis pneumonia pericarditis and repro disorders
tetracycline res strains exist

Question 21

Psittici causes

Answer 21

Clinical signs often diarrhoea anorexia resp distress sinusitis rhinitis conjunctivitis
Parrots game birds pigeons poultry
Zoonotic assoc with resp infections

Question 22

Felis causes

Answer 22

Conjunctivitis and rhinitis in cats esp kittens, rarely zoonotic
Vacc for cats exists

Question 23

Pecorum causes

Answer 23

Enteritis conjunctivitis pneumonia polyarthritis ecephalomyelitis metritis mastitis
Ruminants pigs koalas other marsupials
Most common of sheep can complicate EAE diagnosis
Koalas cause keratoconjunctivitis (blindness) UTIs and GTI

Question 24

Abortus causes

Answer 24

OEA and EAE
Leading diagnosed cause of abortion in sheep rarely abort more than once due to it
Usually causes late abortions and still births or weak offspring
Fetus isnt necrotic but placenta often inflamed with visible lesions and covered with exudate
EB can be Giesma stained from placenta or vaginal discharge

Question 25

What happens if abortus contracted in diff gestation stages

Answer 25

During early - abort late in gest

Outwith gest - abort towards end of next one

Question 26

Abortus pathogenesis

Answer 26

Ingestion or inhalation
Localisation to tonsils/lymph nodes
Dissemination
Latent, persistent or intermittent infection
Placentitis
Foetal infection
Abortion/still birth/weak or sub clinically infected lambs