CHILD WITH SHORT STATURE

Question 1

Constitutional short stature DDx:

5

Answer 1

1. GH deficiency.
2. Hypothyroidism.
3. Chronic renal insufficiency.
4. Genetic causes.
5. Cystic fibrosis.

Question 2

Constitutional short stature workup:

11

Answer 2

1. Physical exam.
2. CBC.
3. Electrolytes.
4. GH stimulation test.
5. IGF-1, IGFBP-3 levels.
6. TSH, FT4.
7. XR—hand.
8. US—renal and cardiac.
9. Sweat chloride test.
10. BUN/Cr.
11. Karyotype.