Chemistry - Acid-Base Flashcards
What is the formula for pH?
pH is equal to -Log[H+]
What regulates bicarbonate?
Bicarbonate is regulated by Kidneys
What regulates carbonic acid?
Carbonic acid is regulated by Lungs
How is carbonic acid calculated?
Carbonic acid is equal to pCO2 x 0.03
What is the Henderson-Hasselbalch equation?
pH = 6.1 + log [HCO3]/[pCO2] x 0.03
What is the normal HCO3- to pCO2 ratio?
Normal HCO3- to pCO2 ratio is 20:1
What characterizes Respiratory Acidosis?
↓ pH, ↑ pCO2, N HCO3-
How do kidneys compensate for Respiratory Acidosis?
Kidneys retain HCO3- and excrete H+
What characterizes Metabolic Acidosis?
↓ pH, N pCO2, ↓ HCO3-
How does the body compensate for Metabolic Acidosis?
Hyperventilation (blow off CO2)
What characterizes Respiratory Alkalosis?
↑ pH, ↓ pCO2, N HCO3-
How do kidneys compensate for Respiratory Alkalosis?
Kidneys excrete HCO3 and retain H+
What characterizes Metabolic Alkalosis?
↑ pH, N pCO2, ↑ HCO3
How does the body compensate for Metabolic Alkalosis?
Hypoventilation (retain CO2)
What is the effect of Hyperventilation on pCO2, pH, and pO2?
↓ pCO2, ↑ pH, ↑ pO2
What is the effect of a specimen exposed to air?
↓ pCO2, ↑ pH, ↑ pO2
What happens to a specimen at RT > 30 min?
↑ pCO2, ↓ pH, ↓ pO2