CHEMICAL RESIDUES AND ANIMAL FIBERS Flashcards
Chemical residues can be found in the following:
-animal tissues
-milk and eggs after the administration of Veterinary drugs and medicated premixes
-application of pesticides to animals
-Consumption of stock feeds previously treated with agricultural chemicals
Systems that have been established to ensure that chemical residues in food do not constitute an unacceptable health risk.
Regulatory and monitoring systems
What are the considerations to ensure the safety of products?
MRL- Maximum Residue Limites
Withdrawal period
Residue programs consists of the following:
Monitoring
Surveillance
This randomly samples tissues from animals at slaughter.
Monitoring
By comparison, sample tissues from animals suspected of violative residues on the basis of clinical signs or herd history.
Surveillance
Key parameters derived in the safety and residue evaluations
- ADI(Acceptable Daily Intake)
- Safe Concentration
- MRL, or tolerance
- Target tissue
- Withdrawal Time
Amount of Veterinary drug, expressed on a body weight basis, that can be ingested daily over a lifetime without an appreciable risk to human health.
ADI(Acceptable Daily Intake)
Maximal allowable concentration of total residues of toxicology concern in edible tissue.
Safe Concentration
Safe Concentration is calculated from
ADI
Maximal consideration of residue resulting from the use of Veterinary drug that is legally permitted as acceptable in or on a food..
MRL, or tolerance
The edible tissue with residues that deplete to a concentration below the MRL at a slower rate compared with other edible tissues.
Target tissue
Target tissue is frequently the:
Liver
Kidney
The period of time between the last administration of a drug and the collection of edible tissue or products from a treated animal that ensures the total residues deplete to below the safe Concentration, and the marker residue depletes to below the MRL.
Withdrawal time
Withdrawal time in cattle is 3 days
Chlorteracycline