Chem U7 Vocab Flashcards
kallmann’s syndrome
impairs sense of smell and delays puberty
androgen excess
causes ambiguous genitalia in female infants and developed puberty in both males and females
congenital 21 hydroxylase deficiency
accumulation of intermediate 17-hydroxyprogesterone in neonates and infants resulting in failure to live
acquired 21 hydroxylase deficiency
seen in adult women resulting in excessive hair growth, menstrual irregularities, and infertility
conn syndrome
making excess mineralocorticoid resulting in increased sodium and volume retention
adrenal insufficiency
inadequate production of cortisol and other hormones
primary - inadequacy of cortisol or aldosterones
secondary - stimulates adrenal hormone release for insufficient impact cortisol or aldosterones
tertiary - lack of CRH production
addison’s disease
primary hypoadrenalism
decrease function in the adrenal gland resulting in decrease mineralocorticoids and glucocorticoids
cushing’s syndrome
increased cortisol from causes (except pituitary ACTH)
cushing’s disease
increased ACTH levels specifically in pituitary gland (secondary)
dexamethasone suppression testing (DST)
acts like cortisol to suppress CRH and ACTH with negative feedback mechanisms
low dose - initial screening
high dose - used specifically for overproduction of ACTH
pheochromocytoma
rare catecholamine tumors in the adrenal medulla
paraganglioma
rare catecholamine tumors in the neural ganglia of the CNS
negative feedback loop
more product is made throughout the pathway, resulting in a decrease in production of itself, stopping earlier steps in the process
positive feedback loop
more product is made throughout the pathway, resulting in a increase in production of itself, stopping earlier steps in the process
hypothalamus
secretes releasing hormone
