Chapter 9 Pedigree Analysis

Question 1

What type of inheritance is indicated in this pedigree (ALL CARRIERS ARE SHOWN)?

A) Autosomal recessive
B) Mitochondrial
C) X-linked Recessive
D) Autosomal Dominant
E) None of the Above

Answer 1

D) Autosomal Dominant

Question 2

Which of the following individuals MUST be carriers of a rare autosomal recessive
disease?

A) II-1
B) II-2
C) II-3
D) III-1
E) III-2
F) III-4
G) III-5
H) III-7

Answer 2

B) II-2
C) II-3
G) III-5
H) III-7

Question 3

In the Liu et al. paper, what is the meaning of maternal clinical anticipation?

A) Mothers can’t wait for children to be born
B) Mothers present clinical symptoms earlier in their life than their children
C) Children present clinical symptoms earlier in their life than their mothers
D) Children had fewer intron repeats than their mothers
E) None of the above

Answer 3

C) Children present clinical symptoms earlier in their life than their mothers

Question 4

What type of inheritance is indicated in this pedigree (ALL CARRIERS ARE SHOWN)?

A) Autosomal recessive
B) Mitochondrial
C) X-linked Recessive
D) Autosomal Dominant
E) None of the Above

Answer 4

D) Autosomal Dominant