Chapter 7 Sex-linked and Mitochondrial Inheritance

Question 1

True or False?

This pedigree represents possible X-Linked Dominant Inheritance

Answer 1

False

Question 2

True or False?

This pedigree represents possible Mitochondrial Inheritance

Answer 2

False

Question 3

True or False?

This pedigree represents possible Mitochondrial Inheritance

Answer 3

True

Question 4

True or False?

This pedigree represents possible Mitochondrial Inheritance

Answer 4

False

Question 5

More males than females are affected by a disease with this inheritance pattern

A) Autosomal Dominant
B) X-Linked Recessive
C) X-Linked Dominant
D) Homozygous Lethal
E) None of the above

Answer 5

B) X-Linked Recessive

Question 6

Why is patient 1’s mutation “likely pathogenic” and patient 2’s mutation “pathogenic”?

A) Patient 1 is the proband
B) Patient 2’s mutation causes a frameshift
C) Patient 1’s mutation is a mis-sense mutation
D) Patient 2’s mutation will make a longer polypeptide
E) All of the above

Answer 6

B) Patient 2’s mutation causes a frameshift

Question 7

What type of inheritance is indicated in this Punnett square?

A) Heterosis
B) Incomplete Dominance
C) Y-linked
D) Autosomal Recessive
E) None of the Above

Answer 7

A) Heterosis