Chapter 9 Flashcards

1
Q

What is the primary objective of calculating oral liquid doses?

A

To interpret orders and calculate the volume of oral liquid medication necessary to administer ordered doses using ratio and proportion or dimensional analysis.

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2
Q

Define “Beyond Use Date” (BUD).

A

The date assigned by the pharmacy to a reconstituted or repackaged medication beyond which the preparation is no longer considered usable.

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3
Q

What is a “Diluent”?

A

An agent that dilutes a substance; in pharmacy, it is the liquid added to a powder to create a liquid form or to dilute another liquid.

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4
Q

Explain the term “Reconstitution.”

A

The process of adding fluid to a powdered or crystalline form of medication to make a specific liquid dosage strength.

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5
Q

What is the significance of the “Meniscus” in liquid measurement?

A

The curved line that develops on the upper surface of a liquid; it should be read at the bottom of the curve at eye level for accurate measurement.

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6
Q

Describe the difference between a “Solution” and a “Suspension.”

A

A solution is a dosage form where the medication is completely dissolved in the liquid, while a suspension contains small particles of medication dispersed throughout the liquid and usually requires shaking before use.

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7
Q

What is the formula for calculating the volume needed for a specific dose using Ratio and Proportion?

A

(Known Strength) / Volume = (Desired Dose) / x

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8
Q

How do you calculate the volume needed for a dose using Dimensional Analysis?

A

Use conversion factors to cancel units and find the desired volume. Example:
Volume
=
Desired Dose
×
(Volume of Stock /
Strength of Stock)

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9
Q

What is the importance of measuring devices in medication administration?

A

Accurate measuring devices (oral syringes, medication cups) ensure the correct volume is administered, reducing the risk of dosing errors.

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10
Q

What are the common household measurements for liquid medications?

A

1 teaspoon (tsp) = 5 mL, 1 tablespoon (Tbsp) = 15 mL, and 1 ounce (oz) = 30 mL.

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11
Q

What should be done if a calculated dose is not a measurable quantity?

A

Round the dose to the nearest measurable quantity, ensuring it remains within a safe margin (typically within 10% of the prescribed dose).

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12
Q

What is the process for reconstituting powdered medications?

A

Read the label for specific instructions on the volume and type of diluent to use, add the diluent in increments, and shake well after each addition.

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13
Q

Why is it important to follow reconstitution instructions exactly?

A

To ensure the medication is prepared to the correct strength and is safe for patient use.

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14
Q

What is the role of the pharmacist in medication dosing?

A

To verify medication orders, check for potential drug interactions, and ensure patient safety through accurate dispensing.

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15
Q

How should liquid medications be stored after reconstitution?

A

Typically, they should be refrigerated and used within a specified time frame (e.g., 7-14 days) as indicated on the label.

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16
Q

What are the potential consequences of medication errors?

A

Adverse drug reactions, ineffective treatment, increased healthcare costs, and potential harm to patients.

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17
Q

What is the significance of patient education regarding medication?

A

Educating patients about their medications helps ensure adherence, understanding of side effects, and proper usage.

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18
Q

What should be done if a medication order is unclear?

A

Seek clarification from the prescribing physician or pharmacist before proceeding with dispensing.

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19
Q

What is the importance of practice problems in learning medication calculations?

A

They reinforce understanding and application of dosing methods, helping to build confidence in calculations.

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20
Q

What is the recommended approach for measuring oral liquid medications?

A

Use calibrated devices rather than household utensils to ensure accuracy and minimize dosing errors.

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21
Q

What are oral liquid medications? What are the advantages of this form of medication?

A

Oral liquid medications include solutions, tinctures, elixirs, suspensions, and syrups. They are absorbed more quickly than solid medications as absorption begins in the mouth or stomach. They are particularly useful for patients who have difficulty swallowing pills, such as children and the elderly.

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22
Q

How are dosages for liquid medications typically expressed?

A

Dosages for liquid medications are commonly expressed in milligrams per milliliter (mg/mL). This indicates the weight of the medication per unit volume of liquid.

23
Q

What tools are commonly used to measure and administer oral liquid medications?

A

Oral syringes, medication cups, droppers, and dose spoons are frequently used to measure and administer oral liquid medications.

24
Q

Why are household utensils like teaspoons and tablespoons discouraged for measuring liquid medication?

A

Household utensils are not recommended for measuring liquid medication due to their inaccuracy. Calibrated devices provide more precise measurements.

25
Q

What is the meniscus, and how should it be read when measuring liquid medication?

A

The meniscus is the curved upper surface of a liquid in a container. When measuring liquid medications, always read at the bottom of the meniscus at eye level for accuracy.

26
Q

Define “powder volume” in the context of oral liquid medications.

A

Powder volume refers to the space occupied by the powdered medication in a container before any diluent is added. It’s important to account for this volume when reconstituting medications to ensure the correct final volume.

27
Q

What is the “displacement value” of a powder?

A

The displacement value refers to the volume of diluent that is displaced by the powder when it’s reconstituted. In other words, it’s the amount of space the powder takes up in the liquid after it’s dissolved.

28
Q

What is reconstitution? What are the general steps involved?

A

Reconstitution is the process of adding a diluent, usually distilled water, to a powdered medication to create a liquid form for administration.

The medication label provides specific instructions for reconstitution, including the type and amount of diluent to use.

Always follow the instructions carefully to ensure the correct concentration of the medication.

29
Q

Why is a “beyond-use date” (BUD) assigned to reconstituted medications?

A

A BUD is assigned to reconstituted medications because they have a shorter shelf life compared to medications in their original form. After reconstitution, the medication may begin to degrade, making it less effective or potentially unsafe. The BUD indicates the date after which the reconstituted medication should be discarded.

30
Q

What two methods are commonly used for calculating oral liquid medication dosages?

A

The two primary methods are:
1.
Ratio and Proportion: This method sets up a proportion to find the unknown dosage.
2.
Dimensional Analysis: This method uses conversion factors to cancel units and arrive at the desired unit of measurement.

31
Q

A physician orders amoxicillin oral suspension 300 mg tid for 7 days. The medication available is amoxicillin 250 mg/5 mL. How many mL are needed for one dose?

A

Using dimensional analysis:

6 mL are needed for one dose.

32
Q

A physician orders Cefdinir suspension 200 mg every 12 hours for 10 days. The medication on hand is cefdinir 125 mg/5 mL. What volume should be given per dose?

A

Using dimensional analysis:

8 mL should be given per dose.

33
Q

A physician orders 9.1 mL of medication to be administered over a period of 7 days. What is the total volume in mL?

A

We know the dose is 9.1 mL/day and this needs to be given for 7 days. So, the total volume can be calculated as follows:

The total volume required is 63.7 mL.

34
Q

A bottle of ampicillin suspension is marked 125 mg/5 mL. The 200 mL bottle instructs that 158 mL of water be added for an oral suspension. The physician wants the child to receive ampicillin 250 mg qid.

What is the powder volume?

What is the total volume?

What is the dose per dose that the child should receive?

What is this dose in household measurements?

A


Powder Volume: The powder volume is the difference between the total volume and the volume of water added: 200 mL - 158 mL = 42 mL.

Total Volume: The total volume is stated on the bottle as 200 mL.

Dose per Dose: Using dimensional analysis:

The child should receive 10 mL per dose.

Household Measurement: Based on Figure 9.4, 10 mL is equivalent to 2 teaspoons (2 tsp).

35
Q

What is the difference between “Expiration Date” and “Beyond Use Date” (BUD)?

A

The expiration date is set by the manufacturer for the medication’s stability, while the BUD is assigned by the pharmacy after reconstitution, indicating when the medication should no longer be used.

36
Q

What is “Powder Volume”?

A

The space occupied by the powdered active ingredient relative to the total volume of medication after reconstitution; it affects the final volume of the liquid medication.

37
Q

What are the common types of oral liquid formulations?

A

Solutions, suspensions, syrups, elixirs, and tinctures.

38
Q

How should the meniscus be read when measuring liquid?

A

At eye level, reading the bottom of the curve to ensure accurate measurement.

39
Q

What is the significance of using calibrated measuring devices?

A

They provide accurate dosing, which is crucial for medications with narrow therapeutic ranges to avoid toxicity or ineffectiveness.

40
Q

What is the recommended method for calculating doses for children?

A

Use weight-based dosing, often calculated in mg/kg, and adjust based on the child’s age and size.

41
Q

What should be done if a medication is available in multiple strengths?

A

Choose the strength that minimizes the volume needed for the dose to enhance accuracy and ease of administration.

42
Q

What is the role of the “Administration Device”?

A

To ensure accurate measurement and delivery of the medication, especially in pediatric and elderly patients.

43
Q

What are the potential risks of using household utensils for measuring medication?

A

Inaccuracy due to variations in size and shape, leading to potential underdosing or overdosing.

44
Q

What is the importance of shaking suspensions before administration?

A

To ensure the medication is evenly distributed throughout the liquid, providing a consistent dose.

45
Q

How can rounding affect medication dosing?

A

Rounding must be done carefully to stay within a safe margin (typically within 10% of the prescribed dose) to avoid adverse effects.

46
Q

What factors should be considered when determining the appropriate diluent for reconstitution?

A

The type of medication, stability, and specific instructions provided by the manufacturer.

47
Q

What is the significance of patient safety in medication administration?

A

Ensuring the correct dose is given at the right time minimizes the risk of medication errors and enhances treatment efficacy.

48
Q

What should be included in patient education regarding liquid medications?

A

Instructions on proper dosing, potential side effects, storage requirements, and the importance of adhering to the prescribed regimen.

49
Q

What is the process for calculating the total volume needed for a multi-day prescription?

A

Multiply the volume per dose by the number of doses per day and the total number of days prescribed.

50
Q

Why is it important to verify the medication order before dispensing?

A

To ensure accuracy, prevent errors, and confirm that the medication is appropriate for the patient’s condition.

51
Q

What is the recommended storage condition for reconstituted medications?

A

Typically refrigerated, and the specific duration for which they remain stable should be followed as per the label instructions.

52
Q

How should discrepancies in dose calculations be handled?

A

Always recalculate and consult with a pharmacist or physician if the calculated dose seems unusually high or low.

53
Q

What is the importance of practice problems in mastering medication calculations?

A

They help reinforce concepts, improve problem-solving skills, and build confidence in applying calculations in real scenarios.

54
Q

What are the key components to include in a medication label for patient use?

A

Medication name, strength, dosage instructions, storage conditions, expiration or BUD, and any special instructions.