Chapter 88: Rheumatoid Arthritis Flashcards
Rheumatoid arthritis (RA) is a chronic, progressive _______ disease that can affect tissues and organs but principally attacks the joints, producing inflammatory ______.
inflammatory
synovitis
RA involves joints bilaterally and ________, and typically affects several joints at one time.
symmetrically
RA typically affects ______ joints first.
upper
RA is an _______ disease that is precipitated by WBCs attacking synovial tissue.
autoimmune
With RA the______ cause the synovial tissue to become inflamed and thickened.
WBCs
The inflammation can extend to the ______, bone, tendons, and ligaments that surround the joint.
cartilage
Joint _______ and bone erosion can result from these changes, decreasing the joint’s range of motion and function.
deformity
RA is also a systemic disease that can affect any ______ tissue in the body.
connective
Common structures affected are the blood vessels, pleura surrounding the lungs, and ___________.
pericardium
Iritis and _______ can also develop in the eyes as a result of RA.
scleritis
The natural course of RA is one of exacerbations and ______.
remissions.
With RA you use ______ that prevent development of deformity of inflamed joint during ADLs.
adaptive devices
With RA you want to continue using affected joints and ______ to maintain function and range of motion.
ambulating
Rheumatoid Arthritis (RA) Risk Factors
Female gender (3:1 compared to males)
Age 20-50 years
Genetic predisposition
Epstein-Barr virus
Stress
Environmental factors
Older age
- Early signs of RA (fatigue, joint discomfort) are vague and can be attributed to other disorders in older adult clients.
- Joint pain and dysfunction can have a greater effect on older adult clients than younger ones due to the presence of other chronic conditions.
- Older adult clients can be less able to overcome and/or cope with joint pain/deformity.
An expected finding of RA is _____ at rest and with movement.
pain
An expected finding of RA is ______ stiffness.
morning
An expected finding of RA is ______ pain (pain upon inspiration).
pleuritic
An expected finding of RA is _____ mouth aka xerostomia
dry
An expected finding of RA is anorexia/weight loss, ______, paresthesias.
fatigue
An expected finding of RA is having occured a _________ illness/stressor.
recent
An expected finding of RA is joint ____.
pain
An expected finding of RA is lack of ______.
function
An expected finding of RA is joint swelling and ______.
deformity
Join deformities are a _____ signs of RA.
late
Joint swelling, _____, and erythema are common with RA.
warmth
Finger, hands, writsts, _____, and foot joints are really affected.
knees
______ joints affected are the proximal interphalangeal and metacarpophalangeal joints.
Finger
Joints can become deformed merely by completing ______ with RA.
ADLs
An expected finding with RA is subcutaneous _____.
nodules
An expected finding of RA is a ____ (generally low grade).
fever
An expected finding of RA is muscle weakness/ ______.
atrophy
An expected finding _____ sclera and/or abnormal shape of the _____.
redness
pupil
An expected finding are enlarged ______.
lymph nodes
Lab tests for RA
Anti - CCP antibodies Rheumatoid Factor Antibodies Erythrocyte sedimentation rate (ESR) C-reactive protein: positive Antinulcear antibody (ANA) titer Elevated WBCs
The _____ test detects antibodies to cyclic citrullinated peptide. The result is positive in most people who have rheumatoid arthritis, even years before symptoms develop. The test is more sensitive for RA than rehumatoid factor (RF) antibodies.
anti-ccp antibodies
With the ______ test the diagnostic level for RA is 1:40 to 1:60. The expected reference range is 1:20 or less.
Rheumatoid factor antibody
With the Rheumatoid factor antibody test high titers correlate with _____ disease. Other automimmune disease also can increase RF antibody.
severe
Elevated _____ is associated with the inflammation or infection in the body. Other autoimmune disorders can increase levels in this test.
ESR
With ESR _____ to _____ mm/hr is a mild inflammation.
20 to 40 mm/hr
With ESR _____ to _____ mm/hr is a moderate inflammation
40 to 70 mm/hr
With ESR _____ to _____ mm/hr is a severe inflammation.
70 to 150 mm/hr
The ______ test may be done in place of the ESR test.
C-reactive protein: positive
The ______ test is useful for diagnosing disease or monitoring disease activity, and for monitoring the response to anti-inflammatory therapy.
C-reactive protein
an ________ identifies an antibody produced against one’s own DNA.
Antinuclear antibody (ANA) titer