Chapter 7 objectives Flashcards

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1
Q

Reverse transcriptase synthesizes:

viral DNA from RNA.

a positive RNA strand from a negative RNA strand.

viral RNA from DNA.

a negative RNA strand from a positive RNA strand.

A

viral DNA from RNA.

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2
Q

Viruses acquire envelopes around their nucleocapsids during:

replication.

release.

penetration.

adsorption.

A

release.

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3
Q

Infectious naked strands of RNA that affect plants are called

spikes.

viroids.

phages.

prions.

A

viroids.

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4
Q

Viral growth in bird embryos can cause discrete, opaque spots in the embryonic membranes

patches.

pocks.

buds.

plaques.

A

pocks.

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5
Q

Tamiflu is a common medication given for influenza treatment, its action being to protect and block sialic acid molecules on the surfaces of host cells and influenza virus envelopes as they leave the cell. Which statement reflects the mechanism of Tamiflu’s action?

Tamiflu interferes with the replication of +ssRNA from the -ssRNA genome of the flu virus.

Tamiflu interferes with the release of the budding viruses from the infected host cells.

Tamiflu blocks protein synthesis of the viral genome.

Tamiflu interferes with the metabolic properties of the virus.

A

Tamiflu interferes with the release of the budding viruses from the infected host cells.

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6
Q

Which of the following represents a virus family name?

Herpes simplex virus

Picornavirus

Herpesviridae

Enterovirus

Hepatitis B virus

A

Herpesviridae

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7
Q

Infectious protein particles are called

viroids.

spikes.

phages.

prions.

A

prions.

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8
Q

Freshly isolated animal tissue that is placed in a growth medium and allowed to produce a cell monolayer is referred to as a/n _____.

secondary

initial

primary

positive

continuous

A

primary

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9
Q

Select the statement that most accurately describes the action of antimicrobial drugs today.

Antiviral drugs often result in toxic side effects due to their inhibition of host cell activity.

The development of antiviral drug resistance has not been observed, as compared to the high rate of antibiotic resistance seen today.

Antiviral drug treatment is more effective than vaccination against a viral disease.

Effective antiviral drugs have a long history of development and use.

A

Antiviral drugs often result in toxic side effects due to their inhibition of host cell activity.

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10
Q

Which of the following is correct about prophages?

present when the virus is in lysogeny

formed when viral DNA enters the bacterial chromosome

cause lysis of host cells

occur when temperate phages enter host cells

A

Present when the virus is in lysogeny

Formed when viral DNA enters the bacterial chromosome

Occur when temperate phases enter host cells

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11
Q

During lysogeny, an inactive prophage state occurs when the viral DNA is inserted into the host

cytoplasm.

nucleus.

DNA.

cell membrane.

A

DNA

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12
Q

Viral tissue specificities are called

ranges.

tropisms.

virions.

receptacles.

A

tropisms.

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13
Q

Creutzfeldt-Jacob disease is

also called “mad cow disease.”

caused by a chronic latent virus.

a spongiform encephalopathy of humans.

initiated by an oncogenic virus.

A

a spongiform encephalopathy of humans.

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14
Q

The event that occurs in bacteriophage multiplication that does not occur in animal virus replication is:

host cell synthesis of viral enzymes and capsid proteins.

injection of only the viral nucleic acid into the host cell.

assembly of nucleocapsids.

adsorption to the host cells.

A

injection of only the viral nucleic acid into the host cell.

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15
Q

New, nonenveloped virus release occurs by

exocytosis.

lysis.

both lysis and budding.

budding.

A

lysis.

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16
Q

Viral capsids are made from subunits called:

spikes.

peptones.

capsomeres.

envelopes.

A

capsomeres.

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17
Q

Some animals can become infected with multiple influenza virus strains usually associated with other animals. Which statement below describes the result of these infections?

All are possible outcomes.

The viral genomes within the host cells can become recombined.

Major genetic variations in the flu viruses can be reproduced.

A new novel strain of flu may be produced, for which the human population has no immunity.

A

All are possible outcomes.

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18
Q

One of the principal viral capsid shapes is a 20-sided figure with 12 evenly spaced corners referred to as a/n _____ capsid.

icosahedral

complex

helical

spiked

A

icosahedral

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19
Q

A common method for cultivating viruses in the lab is to use in vitro systems called _____ cultures.

cell

egg

plaque

embryo

bacteriophage

A

cell

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20
Q

Viral nucleic acid types include:
Group of answer choices

single-stranded RNA

single-stranded DNA

All of the choices are correct.

double-stranded RNA

double-stranded DNA

A

All of the choices are correct.

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21
Q

When a bacterium acquires a trait from its temperate phage, it is called
Group of answer choices

transformation.

viral persistence.

lysogenic conversion.

translation.

transcription.

A

lysogenic conversion.

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22
Q

Viral spikes
Group of answer choices

are derived from host proteins.

are always present on enveloped viruses.

attach the viral capsid and envelope.

allow bacteria to evade host defenses.

are for recognition among the various types of viruses.

A

are always present on enveloped viruses.

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23
Q

Which of the following will not support viral cultivation?
Group of answer choices

continuous cell cultures

embryonated bird eggs

live lab animals

All of the choices will support viral cultivation.

primary cell cultures

A

All of the choices will support viral cultivation.

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24
Q

The envelope of enveloped viruses
Group of answer choices

is obtained by viral budding or exocytosis.

is identical to the host plasma membrane.

always includes spikes.

makes the virus very susceptible to drug therapy.

is only composed of host endomembrane.

A

is obtained by viral budding or exocytosis.

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25
Q

Satellite viruses are
Group of answer choices

also called viroids.

dependent on other viruses for replication.

the cause of spongiform encephalopathies.

significant pathogens of plants.

A

dependent on other viruses for replication.

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26
Q

Viruses
Group of answer choices

undergo binary fission.

cannot be seen in a light microscope.

are prokaryotic.

contain 70S ribosomes.

A

cannot be seen in a light microscope.

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27
Q

A naked virus only has a/n
Group of answer choices

envelope.

capsomere.

capsid.

antigenic surface.

nucleocapsid.

A

nucleocapsid.

28
Q

What type of phage enters an inactive prophage stage?
Group of answer choices

temporary

temperate

primary

transformed

secondary

A

temperate

29
Q

Viruses exhibit all the following except
Group of answer choices

genes.

metabolism.

ultramicroscopic size.

definite shape.

ability to infect host cells.

A

metabolism.

30
Q

Oncogenic viruses include all the following except
Group of answer choices

measles virus.

HTLV-I and HTLV-II viruses.

Papillomavirus.

Epstein-Barr virus.

hepatitis B virus.

A

measles virus.

31
Q

Which of the following is a type of cytopathic effect?
Group of answer choices

multinucleated giant cells

inclusions in the nucleus

inclusions in the cytoplasm

All of the choices are correct.

rounding of cells

A

All of the choices are correct.

32
Q

How are viroids transmitted?
Group of answer choices

plant seeds

blood products

respiratory secretions

sex

A

plant seeds

33
Q

A/n _____ is the protein shell around the nucleic acid core of a virus.
Group of answer choices

spike

capsid

monolayer

capsomere

envelope

A

capsid

34
Q

Viruses attach to their hosts via
Group of answer choices

host glycoproteins.

viral phospholipids.

viral flagella.

carbohydrate attachments of the viral capsid.

host phospholipids.

A

host glycoproteins.

35
Q

Which of the following is not a typical capsid shape?
Group of answer choices

viroid.

tetrahedral

helical

complex

icosahedron

A

tetrahedral

36
Q

Uncoating of viral nucleic acid
Group of answer choices

does not occur in bacteriophage multiplication.

involves enzymatic destruction of the capsid.

occurs before replication.

All of the choices are correct.

occurs during penetration in the multiplication cycle.

A

All of the choices are correct.

37
Q

Mammalian viruses capable of starting tumors are
Group of answer choices

cytopathic.

oncoviruses.

syncytia.

inclusion bodies.

chronic latent viruses.

A

oncoviruses.

38
Q

The correct sequence of events in viral multiplication is:
Group of answer choices

adsorption, penetration, uncoating, synthesis, assembly, release

penetration, uncoating, synthesis, adsorption, assembly, release

uncoating, penetration, synthesis, assembly, absorption, release

adsorption, release, synthesis, uncoating, assembly, penetration

assembly, synthesis, uncoating, release, penetration, adsorption

A

adsorption, penetration, uncoating, synthesis, assembly, release

39
Q

Viruses that cause infection resulting in alternating periods of activity with symptoms and inactivity without symptoms are called

delta agents.

latent.

viroids.

oncogenic.

prions.

A

latent.

40
Q

A common method for cultivating viruses in the lab is to use in vitro systems called _____ cultures.
Group of answer choices

embryo

cell

egg

plaque

bacteriophage

A

cell

41
Q

Persistent viruses that can reactivate periodically are
Group of answer choices

cytopathic.

inclusion bodies.

oncoviruses.

chronic latent viruses.

syncytia.

A

chronic latent viruses.

42
Q

The activation of a prophage is called
Group of answer choices

transformation.

induction.

activation.

lysogeny.

adsorption.

A

induction.

43
Q

Which of the following is not a viral order in the classification system?
Group of answer choices

Vaccinia virus

Nidovirales

Caudovirales

Mononegavirales

A

Vaccinia virus

44
Q

Two noncellular agents, smaller than viruses, are infectious proteins called _____ and infectious RNA strands called _____.

virions; prions

viroids; phages

prions; phages

prions; capsomeres

prions; viroids

A

prions; viroids

45
Q

Which of the following is not a characteristic of a transformed cell?
Group of answer choices

viral nucleic acid integrated into host DNA

changes in cell surface molecules

alterations in chromosomes

capacity to divide indefinitely

decreased growth rate

A

decreased growth rate

46
Q

Host cells of viruses include
Group of answer choices

bacteria.

All of the choices are correct.

humans and other animals.

plants and fungi.

protozoa and algae.

A

All of the choices are correct.

47
Q

Visible, clear, well-defined patches in a monolayer of virus-infected cells in a culture are called
Group of answer choices

patches.

pocks.

cytopathic effects.

plaques.

buds.

A

plaques.

48
Q

In general, most DNA viruses multiply in the host cell’s _____, while most RNA viruses multiply in the host cell’s _____.
Group of answer choices

nucleus; endoplasmic reticulum

cytoplasm; cell membrane

cell membrane; cytoplasm

cytoplasm; nucleus

nucleus; cytoplasm

A

nucleus; cytoplasm

49
Q

The core of every virus particle always contains
Group of answer choices

DNA and RNA.

capsomeres.

DNA.

enzymes.

either DNA or RNA.

A

DNA and RNA.

50
Q

Classification of viruses into families involves determining all the following characteristics except
Group of answer choices

biochemical reactions.

presence of an envelope.

number of strands in the nucleic acid.

type of nucleic acid.

type of capsid.

A

biochemical reactions.

51
Q

Diagnosis of viral infections sometimes involves analyzing the patient’s blood for specific _____ that the immune system produces against the virus.
Group of answer choices

antibodies

complement proteins

glycoproteins

antigens

A

antibodies

52
Q

Which of the following is not associated with every virus?

capsid

envelope

nucleic acid

capsomeres

A

envelope

53
Q

Viruses with _____-sense RNA contain the correct message for translation, while viruses with _____-sense RNA must first be converted into a correct message.
Group of answer choices

negative; positive

secondary; primary

intermediate; primary

positive; negative

A

positive; negative

54
Q

All of the following pertain to virus envelopes except
Group of answer choices

gained as a virus leaves the host cell membrane.

located between the capsid and nucleic acid.

help the virus particle attach to host cells.

gained as a virus leaves the nuclear membrane.

A

located between the capsid and nucleic acid.

55
Q

Cells grown in culture form a/n
Group of answer choices

plaque.

monolayer.

aggregate.

bilayer.

A

monolayer.

56
Q

Which of the following occurs during assembly?
Group of answer choices

nucleocapsid is formed

nucleocapsid is formed and viral spikes insert in host cell membrane

viral spikes insert in host cell membrane

the viral envelope and the host cell membrane fuse

new viral nucleic acid is formed

A

nucleocapsid is formed and viral spikes insert in host cell membrane

57
Q

Lysogeny refers to
Group of answer choices

viral genome inserting into bacterial host chromosome.

latent state of herpes infections.

altering the host range of a virus.

virion exiting host cell.

A

viral genome inserting into bacterial host chromosome.

58
Q

Viruses that infect bacteria are specifically called
Group of answer choices

viroids.

prions.

bacteriophages.

satellite viruses.

A

bacteriophages.

59
Q

Host range is limited by
Group of answer choices

age of the host cell.

size of the host cell.

type of nucleic acid in the virus.

type of host cell receptors on cell membrane.

A

type of host cell receptors on cell membrane.

60
Q

Helical and icosahedral are terms used to describe the shape of a viral
Group of answer choices

core.

capsomere.

spike.

capsid.

envelope.

A

capsid.

61
Q

Infant wheezing with trouble breathing:

Norovirus
Rubella
Mumps
Polio
Hantavirus
Rotavirus
Respiratory Syncytial Virus

A

Respiratory Syncytial Virus (RSV)

62
Q

Nausea, vomiting, fever sometimes associated with cruise ships, nursing homes

Norovirus
Rubella
Mumps
Polio
Hantavirus
Rotavirus
Respiratory Syncytial Virus

A

Norovirus

63
Q

Vaccine preventable, may cause paralysis, attempts to eradicate underway

Norovirus
Rubella
Mumps
Polio
Hantavirus
Rotavirus
Respiratory Syncytial Virus

A

Polio

64
Q

In 1964, 20,000 babies were born with defects due to this virus

Norovirus
Rubella
Mumps
Polio
Hantavirus
Rotavirus
Respiratory Syncytial Virus

A

Rubella

65
Q

May cause serious viral gastroenteritis in infants, leading cause of viral gastroenteritis worldwide, newer vaccine available

Norovirus
Rubella
Mumps
Polio
Hantavirus
Rotavirus
Respiratory Syncytial Virus

A

Rotavirus

66
Q

Rodent control may prevent this; remember to never sweep a shed with rodent feces!

Norovirus
Rubella
Mumps
Polio
Hantavirus
Rotavirus
Respiratory Syncytial Virus

A

Hantavirus

67
Q

Inflammation of salivary glands

Norovirus
Rubella
Mumps
Polio
Hantavirus
Rotavirus
Respiratory Syncytial Virus

A

Mumps