Chapter 7: Membrane Structure and Function Flashcards
plasma membrane
boundary that separates living cell from its surroundings
most abundant lipid in membrane
phospholipids
amphipathic
contains hydrophilic (head) and hydrophobic (tail) regions
fluid mosaic
membrane is fluid structure with mosaic of protein
who discovered the fluid mosaic model
singer and nicolson
what type of studies supported fluid mosaic model
freeze-fracture
as temp cools what happens to membrane
becomes less fluid, more solid; membrane can solidify
which types of membranes are more fluid
rich in unsaturated fatty acids
function of cholesterol in membrane
prevent membrane from becoming too solid when cold, too lquid when warm
why do variations of lipid composition of membrane occur
adaptations to environment
peripheral proteins
bound to surface of membrane, sticks out on one side
integral proteins
penetrate hydrophobic core (transmembrane)
glycolipid
has carbohydrate chain instead of hydrophilic head
glycoproteins
carbohydrate chain bonded to protein
6 functions of membrnae proteins
transport, enzymatic activity, signal transduction, cell-cell recognition, intercellular joining, attachment to cytoskeleton and extracellular matrix
external carbohydrates may vary among
species, individuals, and cell types
HIV requires what to enter cell
CD4 and CCR5 receptors
why are some individuals resistant to HIV
do not have CCR5 receptors
assymetrical distribution of proteins, lipids,and carbs in membrane determined when
membrane is built by ER and golgi bodies
hydrophobic molecules can
dissolve in lipid bilayer and pas through membrane
what type of molecules do not cross through membrane easily
polar molecules
transport proteins
allow passafe of hydrophilic substances across membran; specific to a substance
two types of transport proteins
channel, carrier
channel protein
have hydrophilic channel that certain molecules/ions can use s tunnel