Chapter 7 Flashcards
1
Q
monosomy
A
-absence of a chromosome in a cell
2
Q
trisomy
A
-presence of an extra chromosome in a cell
3
Q
Turner’s syndrome
A
- absence of one X chromosome
- most common in females
- infertile, short, low estrogen
4
Q
Triple X syndrome
A
- extra X chromosome
- most common in females
5
Q
Klinefelter’s syndrome
A
- extra X chromosome
- most common in men
- infertile, underdeveloped, more feminine build
6
Q
XYY syndrome
A
- extra Y chromosome
- most common in males
7
Q
Down syndrome
A
- most common chromosomal abnormality
- trisomy of small chromosome 21
- 1 in 50 if mother is >40 years old
8
Q
harmful drug to fetus: A
A
no risk to fetus
9
Q
harmful drug to fetus: B
A
-no evidence of risk to fetus
10
Q
harmful drug to fetus: C
A
-risk to fetus cannot be ruled out
11
Q
harmful drug to fetus: D
A
- positive evidence of risk to fetus
- drug is needed to treat patients and there is no safer alternative
12
Q
harmful drug to fetus: X
A
- absolutely contraindicated in pregnancy
- Accutane
13
Q
amniocentesis
A
- usually performed between 14th and 18th week of pregnancy
- primary use: prenatal detection of chromosomal abnormality
- indications: over 35, pervious child with down syndrome, known chromosome abnormality, risk of fetal genetic disease
- complications: ruptured membrane, preterm labor, infection
14
Q
chorionic villus sampling (CVS)
A
- small catheter inserted through cervix to the site where villi are attached on the uterus
- usually performed between 8th and 10th week
- complication: spontaneous abortion, limb deformities in fetus
