Chapter 7 Flashcards

1
Q

Define sexual differentiation

A

A fetus following a unique developmental path according to its sex.

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2
Q

When does sexual differentiation begin?

A

Around the 5th week of gestation

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3
Q

What to fetus begin developing into before differentiating?

A

Female. The presence of the Y-chromosome overrides the “default setting”.

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4
Q

What is Turner Syndrome?

A

People with only 1 X-chromosome

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5
Q

Define the pseudoautosomal region

A

The ends of the sex chromosome. They are homologous with each other, allowing for alignment between the X & Y chromosomes during meiosis.

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6
Q

What is the SRY gene?

A

Sex-determining region of the Y-chromosome. Produces the testes determining factor

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7
Q

Define the testes determining factor

A

A transcription factor that causes testes development and male development.

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8
Q

Define a transcription factor

A

Induces transcription/activation of many other genes

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9
Q

How many genes does the Y-chromosome have?

A

~150 poorly-understood genes. Previously thought as a wasteland of junk DNA (this is not true!)

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10
Q

What happens to people who lose their Y chromosome after development?

A

Higher risk of cancer and addition, impaired immunity against sicknesses.

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11
Q

How many genes are on the X-chromosome?

A

~1000 genes

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12
Q

What genes are on the X chromosome?

A

Diverse biological processes including sexual development, immunity, and cognitive development

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13
Q

Why must one of the X chromosomes in females be inactivated?

A

2 active copies of the X is harmful to health, so 1 X chromosome must be inactivated in each cell.
Each cell randomly inactivates a different X.

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14
Q

Define X inactivation

A

AKA dosage compensation. When one X chromosome is inactivated in each female cell.

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15
Q

How does X-inactivation occur?

A

One X-Chromosome produces an RNA molecule called Xist. Xist RNAs coat the other X chromosome, causing it to condense and ecome nonfunctional.

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16
Q

Define Barr Body

A

A condensed X-chromosome that has no gene expression.

17
Q

Define sex ratio

A

Ratio of males : females in a population

18
Q

Define primary sex ratio

A

Amount of males:females at CONCEPTION

19
Q

Define secondary sex ratio

A

Amount of males:females at BIRTH

20
Q

What are the primary and secondary sex ratios?

A

1.05male:1female

21
Q

Why are these ratios slightly skewed?

A

Males have a higher mortality rate. Since they take on more societal roles and are more risk-taking/reckless, a slight amount more of men are born.

22
Q

How is a fetus’ sexual development influenced?

A

By the environment of their mother

23
Q

How can the mother’s environment influence sexual development?

A
  • Slight alteration of the primary/secondary sex ratio
    -Impair male masculinity or female femininity.
24
Q

How can a mother’s environment alter primary/secondary sex ratios?

A

Due to the Willard-Trivers Hypothesis. Causes an asymmetric breeding by gender, as all females have a chance to reproduce but not all males reproduce (some DONT reproduce, some reproduce a lot)

25
Q

Define the Willard-Trivers Hypothesis (4points)

A
  • A stressful environment creates a low-quality child
    -A low quality female is more fertile than a low-quality male
    -A high quality male is more fertile than a low-quality female
    -To maximize fecundity, there is a bias of offspring gender towards female in a stressful envrionment, and towards male in a non-stressful/good environment.
26
Q

How can a mother’s environmnt influence masculinity/femininity?

A

Maternal stress results in high cortisol, which can cause many health problems in the fetus.

27
Q

What does high cortisol do to a fetus?

A

Impairs testosterone surge in male fetus, hindering normal male sexual development and altering behavior.
Female fetus’ are generally more resilient to cortisol leels.

28
Q

What 2 main environmental factors can influence masculinity/femininity?

A
  • Maternal psychological stress
  • Endocrine-disrupting chemicals
29
Q

Since infertility rates are rising….

A

Society is dying

30
Q

Define heterogametic

A

Sex has 2 different chromosomes in a species (ex. male in humans are XY)

31
Q

Define homogametic

A

Sex has 2 of the same chromosomes (ex. females in humans are XX)

32
Q

Define hermaphrodites

A

Species tht have both testes and ovaries

33
Q

What is an example of a hermaphrodite?

A

Nematodes (C. elegans).
Males can impregnate hermaphrodites, and hermaphrodites can also impregnate themselves.

34
Q

Define temperature-dependent sex determination

A

Higher or lower temperature in the environment results in an alteration of the sex while a species is in fetus/egg.