Chapter 6 VIRUSES

Question 1

Spike

Answer 1

Attachment proteins, allow virus to attach to host cell

Question 2

Capsid

Answer 2

Repeating units of proteins in a shell surrounding a viral genome

Question 3

What are the two shapes of capsids?

Answer 3

icosahedral = 20 equilateral triangles. Helical = circular, arm floaties

Question 4

Infection order

APUSAR

Answer 4

Adsorption, penetration, uncoating, synthesis, assembly, release.

Question 5

Adsorption

Answer 5

Virus spike absorbs to receptor sites on host cell

Question 6

Penetration

Answer 6

Host cell membrane is penetrated by whole virus/virus DNA

Question 7

Uncoating

Answer 7

Virus envelope and capsid dissolve, so virus is uncoated

Question 8

Synthesis

Answer 8

Virus takes control over synthetic and metabolic machinery of host cell to begin producing virus DNA/RNA

Question 9

Assembly

Answer 9

Mature virus particles are assembled from growing pool of virus parts

Question 10

Release

Answer 10

Nonenveloped and complex viruses are released on rupture of the host cell.
Enveloped viruses exit by exocytosis.

Question 11

6 HHAPPy DNA viral families

Answer 11

Hepadnavirus = Hepatitis B
Herpesvirus = Herpes, chicken pox
Adenovirus = Upper respiratory issues
Papovavirus = Warts
Parvovirus = Erythema infectiosum
Poxvirus = smallpox

Question 12

5 RNA viral families

Answer 12

Piconavirus = Hepatitis A, polio
Togavirus = Rubella
Orthomyxovirus = influenza
Flavivridae = West Nile virus
Filovirus = Ebola
Retrovirus = HIV/AIDS

Question 13

latent infection

Answer 13

dormant, inactive infection

Question 14

oncogenes

Answer 14

cause cancer

Question 15

lytic cycle

Answer 15

make phages and lyse out of cell

Question 16

prions

Answer 16

defectively folded proteins

Question 17

prion dieases

Answer 17

Creutzfelt-Jakob. scrapie, mad cow disease