Chapter 6 - Skeletal System Flashcards
Function of Skeletal System & components
function: framework for the body
components: bones, cartilages, joints
Cartilage Tissue
- no blood vessels - only type of CT w/no blood vessels
- no nerves
- components - ground substance, cells, fibers
- surrounded by perichondrium
Cartilage Tissue - highest water content of all CT
H2O–most abundant molecule in cartilage; designed to be flexible & comprehensible (bear weight)–high water content allows this
Ground substance (component of cartilage)
80% water, adhesion proteins, proteoglycans (holds water)
Cells (component of cartilage)
chondroblasts, chondrocytes
Fibers (component of cartilage)
mostly collagen
Perichondrium
dense CT covering the cartilage
Functions of Perichondrium
- protects
- Appositional growth
- has some blood vessels (source of O2 & nutrients that cartilage relies on)
Chondroblasts
scattered cells in perichondrium; make cartilage thicker
Chondrocyte
inside “wells” that are inside mature cartilage; no longer productive but maintain tissue
Lacunae
“wells”
Cartilage Growth
- Appositional growth
2. Interstitial growth
Appositional growth (Cartilage Growth)
chondroblasts w/in perichondrium produce tissue; THICKENS cartllage; occurs throughout LIFETIME
Interstitial Growth (Cartilage Growth)
“inside tissue”; chondroblasts inside cartilage produce tissue; way cartilage LENGTHENS; chondroblasts inside tissue as well & able to make cartilage inside; occurs in YOUNGER YEARS
3 Types of Cartilage
- Hyaline cartilage - most flexible; thin collagen fibers
- Elastic cartilage - stretchy; collagen & elastic fibers
- Fibrocartilage - denser; compressible; thick collagen fibers; strongest cartilage
Hyaline Cartilage Locations
costal cartilage, articular cartilage, tip of nose, trachea, parts of larynx, epiphyseal plate
Elastic Cartilage Locations
outer ear, epiglottis (top of larynx; prevents food/drink from getting into respiratory system)
Fibrocartilage Locations
intervertebral discs (between vertebraes so we can move our spine), pubic symphysis (between coxal bones)
Functions of Bones
- Support
- Protection - vital organs
- Assist in movement
- Mineral storage - calcium (over 99% stored in bones)
- Homopoiesis - blood cell formation - RBC, WBC, platelets
- Nutruient storage - yellow bone marrow (stores nutrients)
Each bone is an organ
206 bones; 2 or more tissue types & very specific functions in body
Bone qualifies as an organ bc it contains 2 or more tissues types
Bone tissue - CT
Cartilage tissue - CT
Nervous tissue
Blood vessels - epithelial tissue & muscle tissue
Bones are classified by shape
- Long bones
- Short bones
- Flat bones
- Irregular bones
- Sesamoid bones
Long bones (description & examples)
DES: rectangular shaped; middle part like a tube (cannot be flat); one side longer than other side
EX: humerus, femur, phalanges
Short bones (description & examples)
DES: one dimension is about same as other dimension; square shaped
EX: most carpals (wrists) & tarsals (ankles)
Flat bones (description & examples)
DES: very thin (does not have to be flat)
EX: sternum, most of skull bones; scapula, ribs (not cylinder shaped), clavicles
Irregular bones (description & examples)
DES: unusual shaped
EX: vertebrae, coxal bones
Sesamoid bones (description & examples)
DES: bones inside a tendon
EX: patella –only bones in body that are classified as such
206 bones
80 axial bones - head, neck, trunk
126 appendicular bones - arms, shoulders, legs, hips
2 Bone Textures (bone histology)
- Compact bone
2. Spongy bone
Compact bone
solid; strong; outer parts of bone; made of osteons (Haversian system)–repeating unit columns
Structural unit of compact bone
Osteon
Spongy bone
inside of bone; no osteon; bone tissue in irregular pattern; many spaces between bone; spaces contain either red bone marrow (makes blood cells) or yellow bone marrow depending upon bone
Chemical Composition of bone
25% fluid
25% collagen - strongest of fibers
50% calcium salts (inorganic) - hardens bone
Calcium salts (chemical comp of bone) - arranged in a “rock” form
calcium phosphate salts - most abundant
calcium hydroxide salts
Mineral formed from Calcium phosphate salts & Calcium hydroxide salts
hydroxyapatite
Calcium salts deposit on fibers around collagen fibers
Calcium allows it to be hard & collagen allows it to be strong
Calcification
depositing of calcium salts along collagen fibers; hardening of bone tissue
4 Cells located in Bone:
- Osteogenic cells
- Osteoblast cells
- Osteocyte cells
Above 3 related to each other - Osteoclast cells
Osteogenic cells
Function: dividing cells; almost like stem cells; source of other types of bone cells; develops into osteoblasts; makes organic matter unique to bone tissue
Osteoblast cells
Function: makes bone tissue; form material unique to bone tissue
Osteocyte cells
Function: maintain bone tissue; live in “wells” -lacunae; surrounded by bone tissue
Osteoclast cells
Function: break down older bone tissue; bone destroying cells;
Gross Anatomy of a Long Bone
- Diaphysis
- Epiphysis
- Metaphysis
- Periosteum
- Endosteum
Diaphysis (gross anatomy of a long bone)
“hollow tube shaft”; made of compact bone;
medullary cavity - space inside of tube; contains yellow bone marrow
Epiphysis (gross anatomy of a long bone)
ends of bones; articular cartilage at end;
What make bone lightweight
medullary cavity & spongy bone
Metaphysis (gross anatomy of a long bone)
region between diaphysis & epiphysis; contains epiphyseal plate/line
Epiphyseal plate (Metaphysis)
hyaline cartilage; young bones; in children & young teens; LENGTHENS LONG BONES
Epiphyseal line (Metaphysis)
bone tissue: in adults; doesn’t lengthen bone; epiphyseal plate changed over to epiphyseal line
Periosteum (gross anatomy of a long bone)
dense CT surrounding outside of bone; for protection; contains osteoblasts & osteoclasts; layer of CT
Endosteum (gross anatomy of a long bone)
CT that lines the interior cavities of the long bones; contains osteoblasts (replaces bone tissue) & osteoclasts (breaks down old bone tissue); bone replacement & turnover occurring inside of bone
Gross Anatomy of Short, Flat, Irregular, & Sesamoid Bones
- compact bone on outside & spongy bone in middle & bone marrow fills spaces in spongy bone spaces
- simple structure
- periosteum & endosteum (lines spongy bone cavity)–similar to long bone
Red Bone Marrow
produces all blood cells–RBC, WBC, platelets; inside spongy bone cavity
Locations (in adults) where red bone marrow is formed
ribs, sternum –flat bones;
vertebrae, coxal bone - Irregular bones;
head of humerus & head of femur - long bones
in a very young child or baby
every single bone has red bone marrow; as child gets older, yellow bone marrow replaces red bone marrow
Yellow bone marrow
in medullary cavities;
Location: head, arms, legs, fingers, etc
Bone Development (Changes in Bone)
- Embryonic Development - before birth
a. Intramembranous ossification
b. Endochondral ossification - Post-natal bone growth - after birth
a. Interstitial growth
b. Appositional growth
Ossification
process of bone formation; begins around 8 wks (in womb)
Intramembranous ossification (Embryonic development0
forms skull bones; bone tissue forms inside of mesenchyme; osteoblast cells develop & then it gets calcified
Mesenchyme
common origin of all CT; embryonic CT; membrane
Endochondral ossification (Embryonic development0
occurs @ same time as intramembranous; forms most other bones below the head; starts from HYALINE cartilage; cartilage tissue is broken down & replaced with bone tissue; cartilage is destroyed by calcification; occurs along diaphysis; cartilage–avascular–diff is blood–cartilage & bone; osteoblasts come into spaces & bone tissue is formed; predominant way
Interstitial growth (Post natal bone growth)
epiphyseal plate lenghtens bone
Appositional growth (Post natal bone growth)
Periosteum thickens bones; growth from surrounding tissue
Regulation of bone growth (main hormones necessary for bone growth)
- Growth hormone - stimulates bone growth in children
- Sex hormones - 2 functions - a. growth spurt in early teens; rapid growth; b. late puberty - causes epiphyseal plate closure to be converted to bone tissue;
EX. testosterone & estrogen
Regulation of Blood Calcium
negative feedback; maintains blood levels; maintains homeostasis; 9-11 mg
- Calcitonin
- Parathyroid hormone
Calcitonin
Function: lower blood calcium;
Side effect on bone: strengthens bone tissue; calcium is too high, this lowers it
Parathyroid hormone
Function: raise blood calcium; stimulates osteoclasts activity which breaks down bone tissue & puts in blood
Side effect on bone: weakens bone;
calcium too low, this raises it
Bone deposit
osteoblasts form more bone tissue
Bone resorption
osteoclasts break down bone tissue
As we get older, bone get thinner; bone resorption occurs more than
bone deposit
Osteoporosis
bone resorption occurs much faster than bone deposit; most common bone disorder (not enough calcium in persons body)