Chapter 6 - Quiz 3 Flashcards

1
Q

6.1 Sound and the Ear: Physics and Psychology of sound

What are sound waves?

A

-periodic compressions of air, water or other media

-vary in amplitude and frequency

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2
Q

6.1 Sound and the Ear: Physics and Psychology of sound

Define amplitude

A

-the intensity of a sound wave or height of the wave

–in general, sounds of greater amplitude seem louder, but exceptions occur

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3
Q

6.1 Sound and the Ear: Physics and Psychology of sound

Define frequency and what its measured in? (2)

A

-number of compressions per second
-measured in hertz

-sounds higher in frequency are higher in pitch

-a graph of lower frequency would be less waves per distance, so think of less choppy water

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4
Q

6.1 Sound and the Ear: Physics and Psychology of sound

Define pitch

A

-related aspect of perception

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5
Q

6.1 Sound and the Ear: Physics and Psychology of sound

Define timbre

A

-tone quality or complexity

-how someone can tell the difference between a piano and violin playing the same note at the same volume

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6
Q

6.1 Sound and the Ear: Physics and Psychology of sound

Define prosody

A

-when someone conveys emotional information by tone of voice

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7
Q

6.1 Sound and the Ear: Structures of the Ear

What are the three main parts of the ear anatomically distinguished by anatomists?

A

-Outer ear, middle ear, and inner ear.

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8
Q

6.1 Sound and the Ear: Structures of the Ear

What is a part of the outer ear?

A

-pinna and auditory canal

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9
Q

6.1 Sound and the Ear: Structures of the Ear

What is part of the middle ear?

A

-tympanic membrane and ossicles (hammer, anvil, stirrup)

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10
Q

6.1 Sound and the Ear: Structures of the Ear

What structures are part of the inner ear?

A

-cochlea, oval window, hair cells, auditory nerve

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11
Q

6.1 Sound and the Ear: Structures of the Ear

What is the function of the pinna in the outer ear?

A

-helps locate the source of a sound by altering the reflections of sound waves.

-Each person’s pinna is uniquely shaped, requiring individual learning to use this information effectively
-Rabbits have large, movable pinnas for more precise sound localization.

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12
Q

6.1 Sound and the Ear: Structures of the Ear

What role does the tympanic membrane play in the middle ear?

-aka eardrum

A

-vibrates in response to sound waves and transmits these vibrations to the three tiny bones in the middle ear.

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13
Q

6.1 Sound and the Ear: Structures of the Ear

What are the three tiny bones in the middle ear called? In English and Latin? (2)

A

-hammer, anvil, and stirrup
-malleus, incus, and stapes

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14
Q

6.1 Sound and the Ear: Structures of the Ear

How do the three tiny bones in the middle ear amplify sound?

A

-They transmit vibrations from the tympanic membrane to the oval window with increased force, converting sound waves into waves of greater pressure.

-The tympanic membrane is about 20 times larger than the footplate of the stirrup, amplifying the vibrations like a hydraulic pump.

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15
Q

6.1 Sound and the Ear: Structures of the Ear

What happens when the stirrup vibrates the oval window in the inner ear?

A

-It sets the fluid in the cochlea into motion, which displaces the hair cells and opens ion channels in their membranes.

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16
Q

6.1 Sound and the Ear: Structures of the Ear

What do the hair cells stimulate and where are they located between? (2)

A

-stimulate the auditory nerve (part of the eighth cranial nerve)
-located between the basilar and tectorial membranes of the cochlea

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17
Q

6.1 Pitch Perception

What is place theory in hearing and how does it explain our perception of different pitches? What is an example? (3)

A

-Theory: Different parts of the cochlea are activated by different sound frequencies.
-How: Pitch is determined by where hair cells are stimulated along the cochlea.
-Example: In the scenario of a party with a DJ booth where high-energy music with thumping bass is played, the sensation of feeling the bass more intensely near the DJ booth corresponds to the place theory, where the location of stronger vibrations along the basilar membrane indicates higher pitch perception in our brain.

-High-frequency sounds activate the base; low-frequency sounds activate the apex.
-This mapping helps us distinguish different pitches.
-each frequency activates the hair cells at only one place along the basilar membrane, and the nervous system distinguishes among frequencies based on which neurons respond.

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18
Q

6.1 Pitch Perception

What is the downfall of place theory?

A

-various parts of the basilar membrane are bound too tightly for any part to resonate like a piano string

-Essentially, the downfall indicates a discrepancy between the proposed mechanism of the theory and the physical structure of the basilar membrane.

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19
Q

6.1 Pitch Perception

What is frequency theory in hearing? What is an example? (2)

A

-Theory: entire basilar membrane vibrates in synchrony with a sound, causing auditory nerve axons to produce action potentials at the same frequency
-Example: In the context of people clapping at a party to music, where each clap represents a sound wave, the frequency theory suggests that the pitch we perceive is determined by the speed of the claps; thus, in slower music, like a gentle song, where claps occur at a slow, steady pace, our brain interprets the low pitch due to this steady rhythm.

-for example, a sound at 50 Hz would cause 50 action potentials per second in the auditory nerve

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20
Q

6.1 Pitch Perception

What is the downfall of frequency theory?

A

-the refractory period of a neuron is typically much lower than the highest Hz of frequencies we hear

-its usually around 1000 Hz, but we can hear much higher frequencies

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21
Q

6.1 Pitch Perception

What is the current theory for how we hear things? Explain it for low, higher, and extremely high frequencies? (3)

-The current theory combines elements of the frequency theory and the volley principle.

A

For low-frequency sounds (up to about 100 Hz):
-frequency theory
At higher frequencies:
-Volley principle explains pitch discrimination up to 4000 Hz.
Beyond 4000 Hz:
-Mechanism similar to place theory used.
-Point of peak vibration on basilar membrane identifies sound frequency.

-soft sounds activate fewer neurons and stronger sounds activate more
-Low frequencies are like synchronized claps representing slower music.
-High frequencies are like claps following the rhythm, even if not perfectly in sync.
-Beyond 4000 Hz, it’s like figuring out the music genre by where the loudest claps are coming from.

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22
Q

6.1 Pitch Perception

What is the volley principle? Use an example to explain. (2)

A

-theory: auditory nerve produces volleys of impulse for sounds up to about 4000 per second
-Example: Imagine a relay race where runners pass a baton to keep up speed. Similarly, groups of neurons take turns firing to keep pace with high-frequency sounds. While no single neuron fires at the sound’s frequency, together they create a volley of impulses to match it.

-The volley principle explains how groups of neurons work together to perceive pitch.
-volleys of impulses for sounds up to about 4000 per second, even though no individual axon approaches that frequency

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23
Q

6.1 Pitch Perception Stop and Check 191

Through which mechanism do we perceive low-frequency sounds (up to about 100 Hz)?

A

-At low frequencies, the basilar membrane vibrates in synchrony with the sound waves, and each responding axon in the auditory nerve sends one action potential per sound wave.

-frequency theory

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24
Q

6.1 Pitch Perception Stop and Check Pg 191

How do we perceive middle-frequency sounds? (100-4000 Hz)?

A

-At intermediate frequencies, no single axon fires an action potential for each sound wave, but different axons fire for different waves, and so a volley (group) of axons fires for each wave.

-volley principle

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25
Q

6.1 Pitch Perception Stop and Check Pg 191

How do we perceive high-frequency sounds above 4000 Hz?

A

-At high frequencies, the sound causes maximum vibration for the hair cells at one location along the basilar membrane.

-similar to place theory

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26
Q

6.1 Auditory Complex

Explain the mechanism by which information from the auditory system is processed in the brain, including the role of subcortical areas and the midbrain. What is the point of this mechanism? (2)

A

-Information from the auditory system undergoes processing in the brain through subcortical areas, with axons crossing over in the midbrain to enable each hemisphere of the forebrain to receive input from the opposite ear.
-This mechanism ensures efficient processing of auditory information in the brain.

-When you hear something, like a bird singing, the sound travels from your ears to deeper parts of your brain. Along the way, the brain makes sure that both sides get information from both ears. So, if the bird is on your left, your right brain also knows about it. This helps your brain quickly make sense of what you’re hearing.

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27
Q

6.1 Auditory Cortex

How does the organization of the auditory cortex parallel the visual cortex? What are the seperate pathways? (3)

A

-the visual and auditory system both have seperate pathways for identifying objects and acting upon them as well as similar consequences to damage (motion deaf)
-pathway in anterior temporal cortex for identifying sounds
-pathway in posterior temporal cortex and parietal cortex for locating sound

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28
Q

6.1 Auditory Cortex

Discuss the role of area A1 in auditory processing, including its response to both real and imagined sounds as described in the text.

A

-A1 (primary auditory cortex) responds not only to real sounds but also imagined

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29
Q

6.1 Auditory Cortex

How does experience influence the development of the auditory system? Use an example.

A

-rearing an animal in constant noise environments makes it harder for them to identify individual sounds

-Experience shapes auditory development like it does with vision.

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30
Q

6.1 Auditory Cortex

Explain the functional differences between damage to the primary visual cortex (area V1) and the primary auditory cortex in terms of resulting sensory deficits. What do individuals with damage to the primary auditory cortex have trouble with? (2)

A

-Unlike damage to the primary visual cortex causing blindness, damage to the primary auditory cortex doesn’t lead to deafness.
-instead, individuals with damage to this area struggle with speech and music perception, but can still identify and localize single sounds, indicating the cortex’s role in processing rather than sensory reception.

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31
Q

6.1 Auditory Cortex

Describe the concept of tonotopic mapping in the auditory cortex and how it relates to the processing of different frequencies of sound. Why does it happen? (2)

A

-Tonotopic mapping in the auditory cortex refers to the spatial arrangement of cells responsive to specific frequencies of sound.
-Cells sensitive to similar frequencies tend to cluster together, forming a spatial representation of the frequency spectrum.

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32
Q

6.1 Auditory Cortex

Discuss the preference of auditory cortex cells for a particular type of cell (complex or simple)

A

-Auditory cortex cells exhibit a preference for complex sounds over single tones, responding best to sounds with dominant tones and harmonics.

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33
Q

6.1 Auditory Cortex

Analyze the significance of the study involving individuals with damage to the auditory cortex and their ability to process words related to sounds, in the context of understanding the role of sensory associations in human concepts. What is its signifigance? (2)

A

-The study shows that when people can’t imagine sounds, words about sounds lose their meaning.
-It reminds us how our senses and words are linked.

-the study supports the theory that human concepts rely on associations with the sensations or actions that initially established them, if you cannot imagine sound then a word relating to sound seems meaningless

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34
Q

6.1 Stop and Check Pg 193

List the four ways the auditory cortex is like the visual cortex.

A

-Both seeing and hearing have pathways for “what” (identifying) and “where” (locating).
-Parts of the brain’s superior temporal cortex handle movement for both sights and sounds. If damaged, it can lead to trouble seeing motion (motion blindness) or hearing it (motion deafness).
-The part of the brain responsible for sight is crucial for imagining visuals, while the part for hearing is crucial for imagining sounds.
-Both the brain areas for seeing and hearing need regular experiences early in life to develop properly.

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35
Q

6.1 Sound Localization

How does the human brain determine the direction and distance of a sound?

A

-By comparing the responses of the two ears.

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36
Q

6.1 Sound Localization

What are the three methods explained that help to figure out where sound is coming from? (3)

A

-difference in time of arrival at the two ears
-difference in intensity between the ears
-phase difference between the ears

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37
Q

6.1 Sound Localization

Explain how the time of arrival of a sound for both ears helps you differentiate location.

A

-If a sound reaches one ear before the other, it indicates the direction of the sound.

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38
Q

6.1 Sound localization

How does the difference in intensity between the ears aid in determining location? What is an example? (2)

-bird song example

A

-The difference in intensity between the ears, caused by the head creating a sound shadow, helps localize high-frequency sounds.

-works best for Hz above 2000 - 3000

-Imagine you’re outside and hear a high-pitched bird on your right side. Because your head creates a sound shadow, the sound is louder in your right ear than your left. Your brain detects this difference and helps you locate the bird’s direction.

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39
Q

6.1 Sound localization

How does phase difference between the ears assist in locating sound? Example? (2)

A

-refers to the difference in the timing of sound wave peaks between the ears, providing information for localizing sounds
-Imagine you’re in a room and someone snaps their fingers to your right. The sound waves reach your right ear slightly before they reach your left ear. This small time gap, known as the phase difference, gives your brain information about the direction of the sound cause you hear the sound at different peaks.

-especially those with frequencies up to about 1500 Hz.

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40
Q

6.1 Sound Localization

Sum up how we localize low and high frequencies and sudden frequencies. (3)

A

-low frequencies with phase differences
-high frequencies by loudness difference
-sudden frequencies by time

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41
Q

6.1 Sound Localization

What happens if you become deaf in one ear? At first and eventually? How do they localize sounds? (3)

A

-Initially, all sounds seem to come from the intact ear.
-Eventually, people learn to interpret loudness cues.
-Louder sounds are perceived to come from the intact ear, softer sounds from the opposite side.

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42
Q

6.1 Sound localization Stop and CHeck Pg 194

Which method of sound localization is more effective for an animal with a small head? Which is more effective for an animal with a large head? Why? (2)

A

-An animal with a small head localizes sounds mainly by differences in loudness because the ears are not far enough apart for differences in time to be useful.
-An animal with a large head localizes sounds mainly by differences in time because its ears are far apart and well suited to noting differences in phase or onset time.

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43
Q

6.1 Individual Differences

What is Amusia? What do they have trouble recognizing? (2)

AKA tone deafness

A

-people who struggle to recognize more subtle differences in tones
-trouble recognizing tunes, when someone is singing off key, do not detec a wrong note, trouble gauging peoples mood off tone of voice

-

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44
Q

6.1 Individual Differences

How does people with Amusia’s brain differ? Why is this significant? (2)

A

-auditory cortex appears normal, but fewer connections to the frontal cortex
-shows the deficit is not in hearing itself, but poor memory or attention for pitch

-implication that amusia results from either an impairment of the prefrontal cortex or input to it from the auditory cortex

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45
Q

6.1 Individual differences: deafness

What are the two categories of hearing loss?

A

-conductive deafness or nerve deafness

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46
Q

6.1 Individual differences: deafnessq

Explain conductive deafness, what is it and how does it occur and treatment? (3)

-AKA as middle-ear deafness

A

-What: middle ear is unable to transmit sound waves to the cochlea
-How: Diseases, infectins or tumorous bone growths obstruct/stop this
-Treatment: may be temporary, otherwise surgery or hearing aids

-because people can still hear themselves, since the cochlea is okay and the auditory nerve, they sometimes think people are just mumbling

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47
Q

6.1 Individual Differences: Deafness

What is nerve deafness? Explain what, how and treatment. (3)

-AKA as inner-ear deafness

A

-What is it: damage to the cochlea, hair cells or auditory nerves
-How: inheritance, disease or exposure to loud noises
-Treatment: Preventing further damage, hearing aids or cochlear implant

-if its confined to one part of the cochla, it impairs hearing of certain frequencies and not others

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48
Q

6.1 Individual differences: Deafness

What is tinnitus?

A

-frequent or constant ringing in the ears

-can be sometimes caused by similar process to phantom limb

49
Q

6.1 Individual Differences: Hearing, Attention and Old age

What do some elderly people struggle to hear, despite having hearing aids? Explain how this process comes about? (3)

A

-filtering out irrelevant noise becomes harder
-language areas of the cortex have become less responsive. –Also, auditory areas of the brain have decreased levels of inhibitory neurotransmitters, and the result is decreased ability to focus attention on one speaker in a noisy environment.

50
Q

6.2 Vestibular Sensation

What does the vestibular organ do for us? What does this help us achieve? (3)

A

-detects direction of tilt
-amount of acceleration of head
-this info is used for guiding eye movements and maintaining balance

51
Q

6.1 Vestibular Sensation

What does the vestibular organ consist of?

A

-saccule, utricle, and three semicircular canals

-its a modified touch receptor

52
Q

6.2 Vestibular Sensation

How does the vestibular system tell us which way our head is tilting?

A

within the utricle and saccule, otoliths lie next to hair cells and push against/excite them when the head moves

-tell the brain which direction you are moving but also record which direction the head titls when you are at rest

53
Q

6.2 Vestibular Sensation

Describe the three semicircular canals

A

-oriented in three different planes (yes nod, no nod, tilt)
-filled with fluid and lined with hair cells

54
Q

6.2 Vestibular Sensation

How does the vestibular system recognize acceleration of the head?

A

-acceleration of the head causes fluid in one of these canals to move
-fluid then pushes against the hair cells setting up action potentials

-unlike the saccule and utricle, the semicircular canals record only the amount of acceleration not the position of the head at rest
-they are also insensitive to sustained motion

55
Q

6.2 Vestibular Sensation

Compare the vestibular organ in different animal species.

A

-nearly the same size for all mammalian species

56
Q

6.2 Vestibular Sensation

People with damage to the vestibular system have trouble reading street signs while walking. Why? (2)

A

-The vestibular system enables the brain to shift eye movements to compensate for changes in head position.
-Without feedback about head position, a person would not be able to correct the eye movements, and the experience would be like watching a jiggling book page.

57
Q

6.2 Somatosensation

What is the somatosensory system? What does it include? (2)

A

-sensation of the body and its movements
-many senses including discriminative touch, deep pressure, cold, warmth, pain, itch, tickle and the position and movement of joints

-discriminative touch identifies the shape of an object

58
Q

6.2 Somatosensation: Somatosensory Receptors

What does the Pacinian corpuscles receptor respond to and where is it located? (2)

A

-responds to vibration or sudden touch
-any skin area

59
Q

6.2 Somatosensation: Somatosensory receptors

How does the Pacinian Corpuscle respond to vibration or sudden touch? Describe

A

-a sudden/vibrating stimulus bends the neuron membrane, enabling sodium ions to enter, depolarizing the membrane

-this onion like mechanical support of the neuron membrane mean sustained stimulus do not bend the membrane, only sudden movements

60
Q

6.2 Somatosensation: Somatosensory receptors

What does a merkel disk respond to and where is it located?

A

-static touch, any skin area

-responds to light touch, such as when you feel an object
-for example, women can discern smaller differences in texture because on average, they have smaller hands

61
Q

6.2 Somatosensation: Somatosensory receptors

Explain how the cooling system detects temperature and works in the body? What is an example? (2)

-free nerve endings detect temperature and pain and are in any skin area

A

-cold sensitive neurons in spinal cord respond to a drop in temperature
-for example, cell would respond to drop from 39 to 33 C or 33 to 27 C

-think of it as change in temperature (delta T)

-on a very hot day, you might detect a breeze as cool even though the air in the breeze is fairly warm
-cold sensitive neurons adapt fairly quickly and show little response to a constant low temperature

62
Q

6.2 Somatosensation: Somatosensory receptors

Explain how the heating system detects temperature and works in the body? What is an example? (2)

-contrasts cooling system in body

A

-heat sensitive neurons in spinal cord respond to the absolute temperature and do not adapt
-a cell that responds to 44 C will respond the same way regardless of whether the skin was hotter, cooler or the same temperature a minute or two ago

-this is T, vs cooling is change in temperature

63
Q

6.2 Somatosensation: Tickle

What is the difference in your brain’s perception of your own touch and someone elses?

-which is why self-tickling isn’t a thing really

A

-when you touch yourself, your brain comapres the resulting stimulation to the expected stimulation and generates a weaker somatosensory response than you would experience from an unexpected touch

64
Q

6.2 Somatosensation: in the CNS

Where does information from touch receptors in the head go to? How about from receptors below the head? (2)

A

-from the head enters the CNS through the cranial nerves
-information from receptors below the head enters the spinal cord and passes toward the brain through any of the 31 spinal nerves

-these 31 nerves include: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral and 1 coccygeal
-each spinal nerve has a sensory component and a motor component

65
Q

6.2 Somatosensation: in the CNS

What does each spinal cord innervate (connect to) on the body?

-a limited area

A

-Dermatome

-an area that a single spinal nerve connects to
-for example, the third thoracic nerve (T3) innervates a strip of skin just above the nipples as well as the underarm area
-the borders between dermatomes are not so distinct and each dermatome overlaps one-third to one-half of the next dermatome

66
Q

6.2 Somatosensation: in the CNS

Describe the pathway of information starting with somatosensory information, like touch, pressure, or pain.

-start at spinal cord

A

-travels through the spinal cord in seperate pathways toward thalamus, then to primary somatosensory cortex in the parietal lobe

-two parallel strip along the somatosensory cortex respond mostly to skin touch, another two respond mostly to deep pressure and movement of the joints and muscles
-various aspects of body sensation remain mostly seperate all the way to the cortex

67
Q

6.2 Somatosensation: in the CNS

What is essential for touch experience? Explain this using an example (2)

A

-the primary somatosensory cortex is essential
-when weak, brief stimuli are applied to the fingers, people are conscious of only those that produce a certain level of arousal in the primary somatosensory cortex

-thr activity in the cortex will respond to what you experience, not necessarily to what has actually stimulated the receptors

68
Q

6.2 Somatosensation: in the CNS

What happens if there is damage to the somatosensory cortex? Give an example. (2)

A

-impairs body perceptions
-woman couldn’t find elbow, but could point to objects in the room correctly

69
Q

6.2 Somatosensation: in the CNS

In what way is somatosensation several senses instead of one?

A

-We have several types of receptors, sensitive to touch, heat, and so forth, and different parts of the somatosensory cortex respond to different kinds of skin stimulation.

70
Q

6.2 Somatosensation: in the CNS

How do the responses to skin sensations differ between the somatosensory cortex and the insular cortex of the anterior cingulate cortex?

A

-The somatosensory cortex is necessary for conscious perception of the location and type of skin sensation vs the insular cortex and anterior cingulate cortex respond to the pleasantness.

71
Q

6.2 Pain: stimuli and spinal cord paths

Describe the pathway for pain. What receptors does it start with and which axons carry it? Which axons convery sharp or less sharp pain? What NT do the sharp/less sharp pain relate to? (4)

A

-starts with bare nerve endings
-axons carrying pain info have little or no myelin (meaning they conduct impulses relatively slowly)
-thicker axons convey sharp pain, releasing glutamate and neuropeptides like P and CGRP
-thinner axons convey dull pain, releasing glutamate

72
Q

6.2 Pain: stimuli and spinal cord paths

The spinal paths for pain and touch are similar, but what is the important difference?

A

-pain crosses immediately from receptors on one side of the body to a tract ascending the contralateral side of the spinal cord
-touch info travels up the ipsilateral side of spinal cord to medulla, then crosses to other side

73
Q

6.2 Pain: Emotional pain

Painful stimuli also activate a path that goes through the medulla, thalamus, then to amyygdala, hippocampus, prefrontal cortex and the anterior cingulate cortex. What are these areas reacting to? The sensation of pain or the emotional experience of pain?

A

-the emotional experience of pain

-for example, if someone you love is in pain ou experience sympathetic pain that shows up as activity in your cingulate cortex and other cortical areas
-people with damage to the cingulate gyrus still feel pain, but it no longer distresses them

74
Q

6.2 Pain: Emotional pain

Describe how hurt feelings resemble physical pain in several regards. Use an example of less and then more pain. (2)

A

-the ball tossing experiment where someone was left out found that there was activity in the cingulate cortex (emotional pain)
-thinking of an ex-partner caused activity in both the emotional areas (cingulate cortex) and the sensory areas responsive to physical pain

-so they activate the cingulate cortex, like real pain does, and respond to acetaminophen

75
Q

6.2 Pain: ways of relieving pain: opoids and endorphins

How does the brain put brakes on prolonged pain? Explain the definition of that process too. Why was this significant? (2)

-cause once you know something is painful, you do not need constant reminders at the same intensity

A

-through opioid mechanisms which are systems that respond to opiate drugs and similar chemicals
-this is significant because it shows that opiates mainly act on the nervous system rather than the injured tissue

76
Q

3.2 Pain: ways of relieving pain: opioids and endorphins

What structures do opiates bind to receptors in mostly?

A

-spinal cord and periaqueductal gray area of the midbrain

77
Q

6.2 Pain: relieving pain: opioids and endorphins

What are the nervous systems own version of opiates that attach to the same receptors as morphine and how many types does the brain produce? (2)

-since opiates are man made

A

-endorphins (endogenous morphines)
-it produces several types of endorphins, which relieve different types of pain

78
Q

6.2 Pain: relieveing pain: opioids and endorphins

Explain the gate theory. Explain theory and how. (2)

A

-Theory: non-painful input can close the gates to painful input
-How: spinal cord neurons that recieve messages from pain receptors also recieve input from touch receptors

79
Q

6.2 Pain: relieving pain: opioids

What type of axons does morphine work on? Which explains why it is ineffective against a sharp knife but good for post-surgical pain.

A

-large-diameter axons that are involved in sharp pain

-however long-term use of morphine causes an increase in sensitivity to pain

80
Q

6.2 Pain: relieving pain: cannabinoids

Discuss the use of cannabinoids for pain. What pain does it work on? What are negative side effects? (2)

A

-acts mainly on periphery pain, rather than CNS pain
-side effects include memory impairment

81
Q

6.2 Pain: Relieving pain: cannabinoids and capsaicin

Describe using capsaicin. Explain what pain it is used for and negative side effects. (2)

A

-rubbed onto exterior skin (like icy hot)
-it can cause an excessive buildup of calcium in heat receptors, which damages mitochondria

82
Q

6.2 Pain: relieving pain: placebos

Discuss how placebos have been shown to reduce pain. What are the proposed mechanisms this happens? (2)

A

-placebos reduce both physical and emotional pain. moreso emotional though
-proposed that it is partly through relaxation, distraction and top-down control of sensations and emotions

83
Q

6.2 Sensitization of pain

Why is damaged or inflammed tissue, such as sunburned skin, so painful to touch?

A

-it releases histamines, nerve growth factor and other chemicals to help repair the damage but also magnify the responses of nearby heat and pain receptors

84
Q

6.2 Sensitization of pain

How do nonsteroidal anti-inflammatory drugs, such as ibuprofen, relieve pain?

A

-reducing the chemicals from damaged tissues

85
Q

6.2 Sensitization of pain

Why do some people experience chronic pain? Explain how this comes about

A

-barrage of stimulation to a neuron can potentiate its synaptic receptors to respond more vigorously to the same input in the future

-this is a mechanism essential for learning and memory
-to prevent chronic pain, you want to limit the pain initially experienced

86
Q

6.2 Itch

Explain what itch is. Is it a seperate sensation? How does it occur? Why do we get the need to scratch an itch (3)

A

-itch is a seperate sensation and has special receptors and two spinal cord paths to convey it
-either through histamines during skin damage or by touching plants
-scratching helps remove whatever is irritating your skin, plus pain inhibits itch

87
Q

6.2 Itch

What is some evidence for why itch is a different sensation than pain?

A

-opiates which decrease pain, increase itch

-histamines or capsaicin decrease itch

88
Q

6.3: The Chemical Senses: Taste

What is tatse a result from in the body?

A

-taste buds

-the receptors on the tongue

89
Q

6.3 Taste

What is the area that taste and smell axons converge onto many of the same cells?

A

-endopiriform cortex

-make flavour, a combination of taste and smell

90
Q

6.3 Taste: Taste receptors

Are the receptors for taste true neurons?

A

-no, they are modified skin cells

91
Q

6.3: Taste: Taste Receptors

What similarities do taste receptors have to neurons? How about to skin cells? (2)

A

-Similarity to neurons: excitable membranes, release NT to excite neighboring cells, transmit info to brain
-Similarity to skin cells: gradually sloughed off and replaced (10-14 days)

-human tastes buds in adults lie mainly along the edge of tongue

92
Q

6.3 Taste: How many kinds of taste receptors?

What are the five types of taste receptors outlined in the text? What is the proposed sixth? (2)

A

-sweet, salty, sour, bitter, umami
-fats

-umami is the taste of glutamate
-Jalapenos and other hot peppers produce a hot mouth sensation that is not considered a rasre (Capsaicin)

93
Q

6.3 Taste: How many kinds of taste receptors?

Define adaptation and give an example. (2)

A

-sensitivity to a taste diminishes over time when continuously exposed to that taste stimulus.
-Example: Tasting something sour and then trying something else sour, you will find the second sour thing tastes less sour

94
Q

6.3 Taste: How many tatse receptors?

Define cross-adaptation and give an example

A

-its means you do not show a reduced response to one taste after exposure to another
-Example: you have something sour then try something sweet. The sweet thing will taste just as sweet as normal.

95
Q

6.3 Taste: How many receptors do we have?

What did the experiment on the rats brain cells and taste show us?

A

-shows us that the temporal pattern, or the specific timing and sequence of action potentials, is important for our perception

-they generate different patterns of action potentials over time
-some of these patterns code taste experiences, like bitterness.
-taste is coded by relative activity of different kinds of cells but also by the rythym of responses within a given cell

96
Q

6.3 Taste: Mechanisms of Taste Receptors

How does a saltiness receptor work? What happens when you eat something salty?

A

-it simply permits sodium ions on the tongue to cross its membrane

-chemicals that prevent sodium from crossing the membrane weaken salty tastes

97
Q

6.3 Taste: Mechanisms of taste receptors

How does a sour receptor on the tongue work? What does it detect?

A

-it detects the presence of acids

98
Q

6.3 Taste: Mechanisms of taste receptors

How do sweetness, bitterness and umami receptors mechanisms work?

A

-after a molecule binds to one of these receptors, it activates a G protein that releases a second messenger in cell

-metabotropic synapses

-people have two types of both sweetness and umami receptors each with varying sensitivities

99
Q

6.3 Taste: Mechanisms of taste receptors

Disucss bitterness receptors. What do all bitterness receptors have in common? How many are there? What are the pros and cons of the amount of receptors we have for bitterness? (4)

A

-bitter tastes is detecting toxic chemicals
-about 30 or more
-Pro: we detect a great number of dangerous chemicals
-Cons: because each type of bitter receptor is present in small numbers, we don’t detect very low concentrations of bitter substances

-many bitter chemicals also trigger receptors in the nose, provoking coughing or sneezing

100
Q

6.3 Taste: Stop and Check Pg 213

Suppose you find a new, unusual-tasting food. How could you determine whether we have a special receptor for that food or whether we taste it with a combination of the other known taste receptors?

-think about a definition in this section

A

-You could test for cross-adaptation. If the new taste cross-adapts with others, then it uses the same receptors. If it does not cross-adapt, it may have a receptor of its own.

-Another possibility would be to find some procedure that blocks this taste without blocking other tastes.

101
Q

6.3 Taste: taste coding in the brain

Where do taste nerves project to? Where is this a structure in?

A

-the nucleus of the tractus solitarius (NTS) which is a structure in the medulla

-from the NTS, information branches out reacvhing the pons, lateral hypothalamus, the amygdala, the ventral-posterior thalamus, and two areas of the cerebral cortex
-somatosensory cortex responds to the touch aspect of tongue stimulation

102
Q

6.3 Taste: Taste coding in the brain

What is the insula? Describe the structure (2)

A

-it is the primary taste cortex (within the cerebral cortex)
-the insula in each hemisphere of the cortex recieves input from both sides of the tongue

-certain areas of the insula are dominated by cells responding mainly to sweet tastes whereas other areas are dominated by cells responding to bitter

103
Q

6.3 Taste: Variations in taste sensitivity

What are supertasters?

A

-people with more taste buds who are more sensitive to tastes than other people

104
Q

6.3 Olfaction

Define olfaction and what is it the response t? (2)

A

-sense of smell
-response to chemcials that contact the membranes inside the nose

105
Q

6.3 Olfaction: olfactory receptors

What are the neurons responsible for smell? Where are they located? (2)

A

-olfactory cells
-they line the olfactory epithelium in the rear of the nasal air passages

106
Q

6.3 Olfactory: Olfactory receptors

What does each olfactory cell have in mammals? Where are olfactory receptors located? (2

A

-each has cilia (threadlike dendrites) that extend from the cell body into the mucous surface of the nasal passage
-olfactory receptors are located on the cilia

-cells are bigger than receptors

107
Q

6.3 Olfaction: olfactory receptors

In what way do olfactory receptors resemble metabotropic neurotransmitter receptors?

A

-Like metabotropic neurotransmitter receptors, an olfactory receptor acts through a G protein that triggers further events within the cell.

108
Q

6.3 Olfaction: Messages to the brain

Detail the path that occurs to get the info from an olfactory receptor to the brain

A

-olfactory receptor is stimulated, its axon carries impulse to olfactory bulb which sends acons to the olfactory area of the cerebral cortex

109
Q

6.3 Olfaction: messages to the brain

Describe the process that happens when an olfactory receptor is damaged? Same location and protein? How does the cell know where to grow? (2)

-an olfactory receptor has an average survival time of just over a month

A

-stem cell matures into a new olfactory cell in the same location as the first and expresses the same receptor protein
-each olfactory neuron axon contains copies of its olfactory receptor proteins, which it uses like an idenfitication card to find its correct target in the olfactory bulb

110
Q

6.3 Olfaction: Individual DIfferences

What factors contribute to individual differences in olfactory sensitivity?

A

-People differ in olfactory sensitivity because of genetics, age, and gender.

111
Q

6.3 Pheromones:

Define the vomeronasal organ and where is it located? What does it respond to? (2)

A

-VNO is a set of receptors located near, but seperate from, the olfactory receptors
-it responds only to pheromones

-each VNO receptors responds to just one pheromone

112
Q

6.3 Pheromones

Define pheromones

A

-chemicals released by an animal that affect the behavour of other members of the same species

-humans also respond somewhat to pheromones, although our receptors are in the olfactory mucosa, not the VNO

113
Q

6.3 Pheromones: Stop and Check Pg 220

What is a major difference between olfactory receptors and those of the vomeronasal organ? (2)

A

-Olfactory receptors adapt quickly to a continuous odor, whereas receptors of the vomeronasal organ continue to respond.
-Also, vomeronasal sensations are apparently capable of influencing behavior even without being consciously perceived.

114
Q

6.3 Synesthesia

Define synesthesia

A

-an experience in which stimulation of one sense evokes a perception of that sense and another one also

-Jason is green for example

115
Q

6.3 Synesthesia

What evidence indicates that people learn their synesthetic associations, at least in some cases?

A

-Some people have letter-color synesthesia that matches the colors of refrigerator magnets they played with in childhood.

116
Q

6.3 Synesthesia

If someone reports seeing a particular letter in color, in what way is it different from a real color?

A

-Someone who perceives a letter as yellow (when it is actually in black ink) can nevertheless see it on a yellow page.

117
Q

6.3 Summary Pg 222

Where does the seventh crnail nerve and the ninth and tenth nerve convery infromation from? (2)

A

-7th: anterior two-thirds of the tongue
-9 and 10: posterior tongue and throat

-they interact in complex ways

118
Q

6.3 Summary

What kind of patterns do the olfactory neurons in the cerebral cortex respond to?

A

-complex patterns, such as those of a food