Chapter 6; protein Flashcards
before people experience major events such as heart attack and stroke, the long term narrowing and loss of elasticity in blood vessels are caused by [..]
atherosclerosis
athero - gruel or paste
sclerosis - hardening
atherosclerosis - hardening of the blood vessels
atherosclerosis is an inflammatory disease
yes
the process of atherosclerosis is caused by the presence of elevated levels of cholesterol rich - [..] density lipoproteins (LDLs) in the blood
low
as blood levels of LDL rise, they infiltrate the artery wall, where the LDLs are likely to become oxidized (by reacting with unstable oxygen-containing molecules)
oxidized LDLs cause [..] to cells that line the vessel wall, and this initiates an inflammatory process that attracts [..] blood cells called macrophages inside the arterial lining
injury
white
can factors like smoking and hypertension, cause injury to the arterial wall and trigger inflammation
yes
in atherosclerosis, macrophages take up the oxidized LDLs in a [..] and [..] fashion. these fat-laden macrophages (now called [..] cells) die and deposit their accumulate lipids within the wall of the artery, promoting further inflammation
rapid and uncontrolled
foam
as a result of artery wall inflammation , the lining of the blood vessel becomes more prone to develop a waxy accumulation of [..] and [..], known as plaque. over time plaque development, loss of elasticity, and thickening in the blood vessel walls may make it difficult for [..] to flow through the vessel . this increases the chances of forming blood [..] that either block flow at that location or break off and travel through the bloodstream, blocking blood flow somewhere elsewhere, causing tissue damage and tissue death
cholesterol and triglycerides
blood, clots
when blood flow is blocked in the [..] artery, which supplies blood to the heart, people experience a heart attack, or myocardial infarction. most cases of stroke result when a clot impairs the supply of blood to the [..]
coronary
brain
heart disease begins childhood
yes
more than [..]% of Americans eat a “[..]” diet for heart health, according to the American heart association
90
poor
the average cholesterol level of US adult is just under [..] mg/dl
200
without protein, we wouldn’t be able to breathe, contract our muscles, or complete numerous basic functions
yes
it carries out the biological instructions written in our genes
much of the structural material in the body is provided by protein; its constituents are found in muscle, bone, hair skin, and fingernails
yes
protein carries out many critical functions, such as facilitating chemical reactions through [..] (lipase, amylase, protease), regulating most body and cellular functions as [..] (insulin), maintaining fluid balance (albumin), providing immunity (antibody immunity) and clotting blood, transporters (lipoproteins)
enzymes
hormones
protein needs are relatively high during [..] and [..] periods such as in infancy, in childhood, and during pregnancy
growth and development
for adults with a health body weight, the current Recommended Dietary Allowance (RDA) is 0.8 gram of protein per kilogram of body weight per day (g/kg/d)
yes
weight: 70 kg
0.8 gram per kilogram
70 x 0.8
the acceptable macronutrient distribution range (AMDR) for protein is [..]-[..]% of total kcal
10-35
in the united states, recent nutrition surveys report an average protein intake close to [..]% of total calories, with men consuming about [..] grams and women consuming close to [..] grams
16%
100 grams
70 grams
like carbohydrates and fats, protein is composed of carbon, hydrogen, and oxygen
yes, HOWEVER, it also includes nitrogen
nitrogen in the structure of protein is supplied by [..] acid, which are the building blocks of protein.
amino
individual amino acids are assembled in repeating order to form a larger protein molecule (polymer)
every amino acid consists of a [..] atom of carbon (C); an amino group, which contains nitrogen (written as the chemical formula NH2); and acid group (COOH); and a variable side chain
central
side chains may be as simple as a [..] atom or a group of as many as [..] atoms. its the side chains that distinguish one amino acid from another (for example, tryptophan from serine)
single
19
basically the amino acid structure; is an amino group, the acid group where all amino acids contains an atom of nitrogen, and acid group, a hydrogen atom, and a side chain. a side chain where each amino acid has a unique side chain. a peptide bond forms when the acid group (COOH) of one amino acid is joined with the amino group (NH2) of another amino acid
approximately [..] different proteins carry out the structural and functional roles of the body . proteins are synthesized by linking up to [..] different amino acids by [..] bonds into chains of varying lengths.
22,000
20, peptide