Chapter 6: Energy, Enzymes, and Metabolism Flashcards

1
Q

energy

A

ability to promote change or do work

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2
Q

kinetic energy

A

associated with movement

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3
Q

potential energy

A

due to structure or location

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4
Q

chemical energy

A

the energy in molecular bonds, a form of potential energy

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5
Q

First Law of Thermodynamics

A

energy cannot be created or destroyed, but can be transformed from one type to another

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6
Q

Second Law of Thermodynamics

A

transfer if energy from one form to another increases the entropy of a system

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7
Q

entropy

A

degree of disorder of a system

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8
Q

free energy (Gibbs Free Energy)

A

amount if energy available to do work

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9
Q

spontaneous reactions

A

occur without the input if additional energy

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10
Q

ATP binding site

A

parficular amino acid sequences in proteins used to bind to ATP

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11
Q

catalyst

A

an agent that speeds up the rate of a chemical reaction without being consumed during a reaction

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12
Q

enzymes

A

protein catalysts in living cells

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13
Q

ribozyme

A

RNA molecules with catalytic properties

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14
Q

activation energy

A

initial input of energy to start reaction

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15
Q

active site

A

location where reaction takes place

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16
Q

substrates

A

reactants that bind to active site

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17
Q

enzyme-substrate complex

A

formed when enzyme and substrate bind

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18
Q

lock and key metaphor

A

only the right key (substrate) will fit into the lock (enzyme)

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19
Q

saturation

A

plateau where nearly all active sites are occupied by substrate

20
Q

Michaelis constant (Km)

A

substrate concentration where velocity is half maximal value

21
Q

competitive inhibition

A

molecule binds to active site

22
Q

noncompetitive inhibition

A

lowers Vmax without affecting Km

- inhibitor binds to allosteric site and changes active site shape through binding

23
Q

prosthetic groups

A

small molecules permanently attached to enzyme

24
Q

cofactor

A

usually inorganic ion that temporarily binds to enzyme

25
Q

coenzyme

A

organic molecule thag participates in reaction and is left unchanged afterward

26
Q

ribonuclease

A

found in all living organisms and involved in cleaving RNA molecules

27
Q

metabolic pathways

A

where chemical reactions occur

28
Q

catabolic pathways

A

breakdown cellular components, exergonic

29
Q

anabolic pathways

A

synthesis of cellular components, endergonic, must be coupled to exergonic reaction

30
Q

catabolic reaction

A

breakdown of reactants

31
Q

substrate-level phosphorylation

A

enzyme directly transfers phosphate from one molecule to another molecule
-makes ATP

32
Q

chemiosmosis

A

energy stored in an electrochemical gradient is used to make ATP from ADP and P
-happens in mitochondria and chloroplasts

33
Q

redox reactions

A

electron removed from one molecule is added to another

34
Q

oxidation

A

removal of electrons

35
Q

reduction

A

addition of electrons

36
Q

anabolic reactions (biosynthetic reactions)

A

make large molecules or smaller molecules not available from food

37
Q

gene regulation

A

turn genes on or off

38
Q

cellular regulation

A

cell-signaling pathways like hormones

39
Q

feedback inhibition

A

product of pathway inhibits early steps to prevent over accumulation of product

40
Q

half-life

A

time it takes for 50% of the molecules to be broken down and recycled

41
Q

proteosome

A

a large complex that breaks down proteins using protease enzyme

42
Q

proteases

A

cleave bonds between amino acids

43
Q

ubiquitin

A

tags target proteins to the proteosome to be broken down and recycled

44
Q

lysosomes

A

contain hydrolases to break down proteins, carbohydrates, nucleic acids, and lipids

45
Q

autophagy

A

recycling worn out organelles using an autophageosome