Chapter 6 - Antepartal Tests Flashcards
Screening
not definite
-designed to ID those who are NOT affected by a diasease or abnormality
Diagnostic Tests
give a definite yes or no re if fetus is normal or abnormal
Types of Screening Tests
- AFI
- BPP
- CST
- daily FKC
- multimarker screening [AFP, triple/quad marker)
- NST
- ultrasonography
- nuchal translucency
- umbillical artery doppler flow
- VAS
Types of Diagnostic Tests
- amniocentesis
- CVS
- MRI
- PUBS
- ultrasonography
types of biophysical assessments
- ultrasonography
- umbilical artery doppler flow
- MRI
- *alll screen, not diagnstc
Amniocentesis
needle is inserted thru abdominal wall to get amniotic fluid
- 15 20 wk
- diagnostic for cell growth + chromosomal
Amniocentesis
results
- high bilirubin= hemolytic disease
- pos culture= infectn
- L/S > 2:1 is mature lungs
- L/S < 2:1 immature, risk for RDS
- pos PG= mature lungs
- neg PG = immature
- LBC>50K= mature lungs
- LBC<50K= immature
Amniocentesis risks
- loss
- trauma to fetus/placenta
- bleed/leak of amnio fluid
- preterm labor
- mom infectn
- Rh sensitization bc risk for blood mixing
PUBS percutaneous umbilical blood sampling
- removal of fetal blood fr umbilical cord
- diagnostic test for metab, hematologic, disorders, fetal infectn, fetal karyotyping
- 18 wks
PUBS risks
- loss
- trauma to fetus/placenta
- bleed/leak of amnio fluid
- preterm labor
- mom infectn
- Rh sensitization bc risk for blood mixing
Types of maternal assays
- AFP/MSAFP
- Triple Marker Screen
- Quad Marker Screen
Alpha-FetoProtein [AFP]
aka
Maternal Serum AFP [MSAFP]
AFP is a glycoprotein produced by the fetal liver, GI tract + yolk sac in early gestation
- screening tool for NTD + ventral wall defects
- 15-20 wks
high levels of AFP
- NTD
- anencephaly
- omphalocele
- gastroschisis
low levels of AFP
-trisomy 21 aka down syndrome
abnormal AFP findings will require additional testing such as…
- amniocentesis
- CVS
- ultrasonography
AFP has a high risk for…
false positives
Triple Marker Screen/Quad Marker Screen
- triple: AFP, hCG, + estriol
- quad: +inhibin A
- tests for trisomy (down syndr) + NTD
- 15-16 wks
high levels of hCG + inhibin A
trisomy 21 (down syndrome)
low levels of estriol
Down syndr
Fetal Kick Count FKC
- kicking starts at 16-20wk
- utilized after 28 wks
- palpate ab + track mvmt for 1-2 hrs
FKC norm + abnorm
norm: 10+ w/in 2 hrs; 4+ in 1 hr
abnorm: less than 4 in 4 hrs, contact HCP
Non Stress Test
monitors FHR pattern + acceleration to assess oxygenation
-monitor for 20-40 min