Chapter 6 Flashcards

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1
Q

nuclein (p. 228)

A

The original name given to DNA when it was discovered in the nucleus of cells by Friedrich Miescher in 1869

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2
Q

nucleotide (p. 229)

A

The repeating unit in DNA; it comprises a deoxyribose sugar, a phosphate group, and one of the four nitrogenous bases

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3
Q

X-ray crystallography (p. 230)

A

A technique in which a pure substance is subjected to X-rays; the pattern in which the X-rays bend and spread helps reveal the structure of the pure substance

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4
Q

scientific model (p. 230)

A

a simplified representation of a concept; can be tangible or conceptual

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5
Q

complementary base pairing (p. 231)

A

pairing of the nitrogenous base of one strand of DNA with the nitrogenous base of another strand; adenine (A.) pairs with thymine (T), and guanine (G) pairs with cytosine (C)

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6
Q

point mutation (p. 234)

A

a small-scale change in the nitrogenous base sequence of a DNA; the mutation may be beneficial, harmful, or neutral (having no effect on
the organism)

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7
Q

chromosome mutation (p. 234)

A

an error that involves an entire chromosome or a large part of a chromosome

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8
Q

spontaneous mutation (p. 236)

A

a mutation that is not caused by any outside factors; it occurs randomly

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9
Q

induced mutation (p. 236)

A

a mutation that occurs because of exposure to an outside factor; second-hand smoke increases the chance of developing lung cancer

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10
Q

antibiotic resistant (p. 237)

A

describes strains of bacteria that are no longer susceptible to the effects of antibiotics; are sometimes called “superbugs” and are prevalent in hospital settings

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11
Q

transposon (p. 237)

A

a specific segment of DNA that can move along or between the
chromosomes

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12
Q

transposition (p. 237)

A

the process of moving a gene sequence from one part of the chromosome to another part of the chromosome

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13
Q

microarray (p. 238)

A

a small membrane or glass slide that has been coated in a predictable and organized manner with a genomic sequence

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14
Q

Human Genome Project (HGP) (p. 240)

A

a collaborative worldwide project to sequence the nitrogenous bases in human DNA

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15
Q

human genome (p. 240)

A

the sequence of DNA nitrogenous bases found on the 23 sets of chromosomes in humans

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16
Q

coding DNA (p. 240)

A

a region of DNA that contains a sequence of nucleotides that will be expressed; a gene

17
Q

non-coding DNA (p. 240)

A

a region of DNA that does not contain a sequence of nucleotides that will be expressed

18
Q

functional genomics (p. 241)

A

the study of the relationship between genes and their function

19
Q

model organism (p. 241)

A

an organism that can be used to study biological functions of another organism, due to its genetic similarity

20
Q

DNA bank (p. 242)

A

a database of DNA sequences; the sequences can be from plants, animals, or humans

21
Q

DNA fingerprinting (p. 243)

A

a pattern of bands on a gel that is unique to each individual

22
Q

restriction enzyme (p. 245)

A

a molecule that has the ability to cut DNA at a specific site; different restriction enzymes recognize and cut different sites

23
Q

recombinant DNA (p. 245)

A

fragments of DNA consisting of nucleotide sequences from at least two different sources

24
Q

gene therapy (p. 249)

A

the process by which defective genes in a genome are corrected with a normal copy of the gene

25
Q

target cell (p. 249)

A

one of the cells that contain the faulty gene to be corrected

26
Q

vector (p. 249)

A

any agent, such as a plasmid or a virus, capable of inserting a piece of foreign DNA into a cell

27
Q

Nature vs. Nurture Debate (Triplet Study)

A

● 3 boys placed in different homes - no clue triplets
● multiyear study by child psychiatrist - examining the question of “nature vs. nurture,” - never published, and the study’s materials are being kept at Yale University.

28
Q

Nature vs. Nurture Debate (Mother Rats)

A

Those who mothers were lickers child become lickers and those who were not became non lickers

29
Q

Nature vs. Nurture Debate (FAS)

A

Is a disorder that happens when the mother drinks alcohol while pregnant.

30
Q

Nature vs. Nurture Debate (WWII testing)

A

● 3000 twin sets - 200 survived
● Eugenics is the scientifically erroneous and immoral theory of “racial improvement” and “planned breeding” – believed that they could perfect human beings through genetics and heredity

31
Q

Chromosome

A

(tightly wound DNA)
● chromatin is really in “pieces”(46 in humans)
● when chromatin coils up - making the “pieces” visible - we
call the pieces chromosomes
● chromosomes have 2 parts
○ DNA - the “string”
○ Histone Proteins - the “spools”

32
Q

DNA

A

(DeoxyriboNucleic Acid)
● huge molecule/polymer/macromolecule
● coiled ladder
● sugar phosphate sides
● nitrogen bases (A,C,G,T) make the rungs
○ A + T or C + G

33
Q

Nucleosides (————+ ————-)

A

(N Base + Sugar)

34
Q

Nucleotides ( )

A

(N Base + Sugar + Phosphate Group)

35
Q

What examples of Macromolecules that made from monomers

A

Macromolecules are made from monomers such as glucose, fatty acids, glycerol, amino acids, nucleotides