Chapter 53: Diabetes Flashcards
long acting insulin onset, peak, and duration
onset: 0.8-4 hr
peak: no pronounced peak
duration: 24+ hr
environmental factors include obesity and lack of exercise
type 2 diabetes
primary defect is absent or minimal insulin production
type 1 diabetes
involves BG over 600 mg/dL and increased serum osmolality
hyperosmolar hyperglycemic syndrome (HHS)
these diabetes medications do not cause hypoglycemia when used alone and are good for insulin resistance
thiazolidinediones: pioglitazone (Actos), rosiglitazone (Avandia)
hypoglycemia is defined by a BG level less than ____
70 mg/dL
pathogenesis of foot complications from diabetes
sensory neuropathy–> loss of protective sensation–> unawareness of injury
neurogenic bladder can cause ______________, to treat, empty frequently, using _____________; also use _____________ and _____________
urinary retention, Credé’s maneuver, medications, self-catheterization
manifestations include dehydration; lethargy and weakness early; skin dry and loose; eyes soft and sunken; abdominal pain; anorexia; nausea/vomiting; Kussmaul respirations; sweet, fruity breath odor
diabetic ketoacidosis (DKA)
can affect nearly all body systems, such as gastroparesis, cardiovascular abnormalities, sexual function, and neurogenic bladder
autonomic neuropathy
islet cell antibodies are often present at onset
type 1 diabetes
most common cause of new cases of adult blindness
diabetic retinopathy
cardiovascular abnormalities of autonomic neuropathy (3)
postural hypotension, resting tachycardia, and painless MI
examples of 15 g quick-acting carbohydrate snacks (5)
- 4-6 oz of regular soda, orange juice
- 5-8 lifesavers
- 1 tbsp syrup or honey
- 4 tsp jelly
- commercial dextrose products
Somogyi effect is treated with _____________
a bedtime snack
Microvascular and macrovascular diseases increase risk for injury and infection of _______
feet
two drugs that can delay progression of diabetic nephropathy with albuminuria present
ACE inhibitors
Angiotensin II receptor agonists
Neurontin (gabapentin)
treats sensory neuropathy
symptoms: often none but include fatigue, recurrent infections, may have polyuria, polydipsia, polyphagia
type 2 diabetes
laser destroys ischemic areas of retina
laser photocoagulation
characterized by red-yellow lesions
necrobiosis lipoidica diabeticorum
diagnosis of diabetes involves these four criteria
- A1C 6.5% or higher
- fasting plasma glucose level: 126 mg/dL or higher
- 2-hour plasma glucose level of 200 mg/dL or greater during OGTT using glucose load of 75 g
- In a patient with classic symptoms and random plasma glucose level of 200 mg/dL or greater (repeat testing not needed)
life-threatening syndrome that occurs with type 2 diabetes
hyperosmolar hyperglycemic syndrome (HHS)
vascular/neurological complications frequent
type 1 diabetes, type 2 diabetes
ketosis not present except during infection or stress
type 2 diabetes
when taking metformin, cannot have _____________ with a CT scan (must be off for __________)
increases risk for _______________, which can worsen lactic acidosis
contrast dye that contains iodine (48 hours before and after)
contrast-induced nephropathy (CIN)
bone and joint changes that occur secondary to loss of sensation
neuropathic arthropathy (Charcot’s foot)
microvascular damage to retina
diabetic retinopathy
delay exercise if BG is less than ________ after eating ________ and rechecking after _____________
100, 15 g snack, 15-30 minutes
defect in mobilization of inflammatory cells and impaired phagocytosis can cause this diabetes complication
infection
how many criteria required for diagnosis of diabetes
2 criteria from first 3; 4th criteria alone
intermediate acting insulin onset, peak, and duration
onset: 1.5-4 hrs
peak: 4-12 hrs
duration: 12-18 hrs
rapid acting insulin onset, peak, and duration
onset: 10-30 min
peak: 30 min-3 hrs
duration: 3-5 hrs
hyperglycemia is present upon awakening from GH and cortisol; BG levels between 0200 and 0400 are normal
Dawn phenomenon
do not use this medication in people who drink excess amounts of alcohol
metformin
do not use this diabetes medication in patients with a personal or family history of medullary thyroid cancer
dulaglutide (Trulicity)
hyperglycemia rebounds in the morning after period of hypoglycemia between 0200 and 0400
Somogyi effect
may be thin, normal, or obese
type 1 diabetes
damage to small blood vessels that supply glomeruli of kidney
diabetic nephropathy
most widely used oral agent for diabetes
metformin
nursing management of diabetic ketoacidosis (DKA)
- ensure patent airway; administer O2
- establish IV access; begin fluid resuscitation
- continuous regular insulin drip, 0.1 units/kg/hr
- potassium replacement as needed
more common in young but can occur at any age
type 1 diabetes
manifestations of hypoglycemia (8)
shakiness, palpitations, nervousness, diaphoresis, anxiety, hunger, pallor, altered mental functioning (difficulty speaking, visual disturbances, stupor, confusion, coma)
do not use metformin in patients with _________ disease, ________ disease, or ______________
liver, kidney, heart failure