Chapter 37: Drugs

Question 1

reduced BP

Answer 1

beta-adrenergic blockers

Question 2

increases bleeding with warfarin

Answer 2

fibric acid derivatives

Question 3

encourage patient taking long-acting nitrates to have a nitrate free time of _________ each day

Answer 3

10-14 hours

Question 4

reduced HR (2)

Answer 4

beta-adrenergic blockers
calcium channel blockers

Question 5

makes more of its receptors available to get rid of cholesterol

Answer 5

PCSK9 inhibitors

Question 6

routes of administration of long-acting nitrates

Answer 6

oral, nitroglycerin (NTG) ointment, transdermal controlled-release NTG

Question 7

used in patients with an ejection fraction of <40% (2)

Answer 7

angiotensin-converting enzyme (ACE) inhibitors
angiotensin receptor blockers (ARBs)

Question 8

increases conversion of cholesterol to bile acids

Answer 8

bile acid sequestrants

Question 9

decreased total cholesterol

Answer 9

bile acid sequestrants

Question 10

this drug is used with STEMI

Answer 10

glycoprotein IIb/IIIa inhibitors (during PCI)

Question 11

side effects include dizziness, nausea, constipation, and headache

Answer 11

sodium current inhibitor

Question 12

is given subcutaneously

Answer 12

PCSK9 inhibitors

Question 13

side effects include flushing, pruritus, GI symptoms, orthostatic hypotension

Answer 13

niacin

Question 14

sublingual nitroglycerin (SL NTG) dosage

Answer 14

1 tablet or 1-2 metered sprays

Question 15

increases effects of antihyperglycemic drugs (repaglinide)

Answer 15

fibric acid derivatives

Question 16

HMG-CoA reductase inhibitors are also known as

Answer 16

statins

Question 17

prevents or reverses ventricular remodeling (2)

Answer 17

ACE inhibitors
angiotensin receptor blockers

Question 18

given in patients with a history of MI or LVH

Answer 18

beta-adrenergic blockers

Question 19

reduced cardiac volume (2)

Answer 19

ACE inhibitors
angiotensin receptor blockers

Question 20

used to reduce frequency of angina and treat Prinzmetal’s angina

Answer 20

long-acting nitrates

Question 21

reduced SVR (2)

Answer 21

beta-adrenergic blockers
calcium channel blockers

Question 22

increased risk for rhabdomyolysis when used with fibric acid derivatives, niacin, or erythromycin

Answer 22

simvastatin

Question 23

increased HDL (3)

Answer 23

statins
niacin
fibric acid derivatives

Question 24

inhibits cholesterol synthesis

Answer 24

statins

Question 25

SL NTG may be repeated every ___ minutes up to __ doses

Answer 25

5, 3

Question 26

reduced myocardial contractility (2)

Answer 26

beta-adrenergic blockers calcium channel blockers

Question 27

decreased C-reactive protein

Answer 27

statins

Question 28

can cause cough, angioedema

Answer 28

ACE inhibitors

Question 29

decreases absorption of dietary and biliary cholesterol; combined with statin

Answer 29

ezetimibe

Question 30

may cause headache, dizziness, flushing, orthostatic hypotension

Answer 30

sublingual nitroglycerin (SL NTG)

Question 31

has GI side effects and reduced absorption of other drugs (thiazides, warfarin, digoxin)

Answer 31

bile acid sequestrants

Question 32

known to cause constipation

Answer 32

verapamil

Question 33

side effects include bradycardia, hypotension, wheezing, GI effects, weight gain, depression, fatigue, sexual dysfunction

Answer 33

beta-adrenergic blockers

Question 34

dilate peripheral and coronary arteries and collateral vessels

Answer 34

short-acting nitrates

Question 35

decreased LDL (2)

Answer 35

statins bile acid sequestrants

Question 36

SL NTG gives relief in __ minutes and lasts _____ minutes

Answer 36

5, 30-40

Question 37

side effects include fatigue, headache, dizziness, flushing, peripheral edema

Answer 37

calcium channel blockers (CCBs)

Question 38

monitor this enzyme for myalgia

Answer 38

CK-MM

Question 39

inhibits synthesis of triglycerides

Answer 39

niacin

Question 40

inhibits synthesis of LDL

Answer 40

niacin

Question 41

vasodilation (4)

Answer 41

ACE inhibitors angiotensin receptor blockers calcium channel blockers nitrates

Question 42

contraindicated in patients with severe bradycardia and acute decompensated heart failure

Answer 42

beta-adrenergic blockers

Question 43

monitor when using digoxin

Answer 43

calcium channel blockers (CCBs)

Question 44

most potent statin

Answer 44

rosuvastatin (Crestor)

Question 45

used when inadequate response to other antianginal drugs

Answer 45

sodium current inhibitor

Question 46

these two drugs are used with UA and NSTEMI

Answer 46

heparin glycoprotein IIb/IIIa inhibitors (before or during PCI)

Question 47

two serious adverse effects of rosuvastatin

Answer 47

liver damage, myalgia

Question 48

used with diet therapy and maximum statins

Answer 48

PCSK9 inhibitors

Question 49

cautious use of this medication with asthma and diabetes

Answer 49

beta-adrenergic blockers

Question 50

decreased triglycerides

Answer 50

fibric acid derivatives