Chapter 37: Drugs Flashcards

1
Q

reduced BP

A

beta-adrenergic blockers

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2
Q

increases bleeding with warfarin

A

fibric acid derivatives

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3
Q

encourage patient taking long-acting nitrates to have a nitrate free time of _________ each day

A

10-14 hours

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4
Q

reduced HR (2)

A

beta-adrenergic blockers
calcium channel blockers

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5
Q

makes more of its receptors available to get rid of cholesterol

A

PCSK9 inhibitors

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6
Q

routes of administration of long-acting nitrates

A

oral, nitroglycerin (NTG) ointment, transdermal controlled-release NTG

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7
Q

used in patients with an ejection fraction of <40% (2)

A

angiotensin-converting enzyme (ACE) inhibitors
angiotensin receptor blockers (ARBs)

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8
Q

increases conversion of cholesterol to bile acids

A

bile acid sequestrants

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9
Q

decreased total cholesterol

A

bile acid sequestrants

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10
Q

this drug is used with STEMI

A

glycoprotein IIb/IIIa inhibitors (during PCI)

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11
Q

side effects include dizziness, nausea, constipation, and headache

A

sodium current inhibitor

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12
Q

is given subcutaneously

A

PCSK9 inhibitors

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13
Q

side effects include flushing, pruritus, GI symptoms, orthostatic hypotension

A

niacin

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14
Q

sublingual nitroglycerin (SL NTG) dosage

A

1 tablet or 1-2 metered sprays

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15
Q

increases effects of antihyperglycemic drugs (repaglinide)

A

fibric acid derivatives

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16
Q

HMG-CoA reductase inhibitors are also known as

A

statins

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17
Q

prevents or reverses ventricular remodeling (2)

A

ACE inhibitors
angiotensin receptor blockers

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18
Q

given in patients with a history of MI or LVH

A

beta-adrenergic blockers

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19
Q

reduced cardiac volume (2)

A

ACE inhibitors
angiotensin receptor blockers

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20
Q

used to reduce frequency of angina and treat Prinzmetal’s angina

A

long-acting nitrates

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21
Q

reduced SVR (2)

A

beta-adrenergic blockers
calcium channel blockers

22
Q

increased risk for rhabdomyolysis when used with fibric acid derivatives, niacin, or erythromycin

A

simvastatin

23
Q

increased HDL (3)

A

statins
niacin
fibric acid derivatives

24
Q

inhibits cholesterol synthesis

A

statins

25
Q

SL NTG may be repeated every ___ minutes up to __ doses

A

5, 3

26
Q

reduced myocardial contractility (2)

A

beta-adrenergic blockers
calcium channel blockers

27
Q

decreased C-reactive protein

A

statins

28
Q

can cause cough, angioedema

A

ACE inhibitors

29
Q

decreases absorption of dietary and biliary cholesterol; combined with statin

A

ezetimibe

30
Q

may cause headache, dizziness, flushing, orthostatic hypotension

A

sublingual nitroglycerin (SL NTG)

31
Q

has GI side effects and reduced absorption of other drugs (thiazides, warfarin, digoxin)

A

bile acid sequestrants

32
Q

known to cause constipation

A

verapamil

33
Q

side effects include bradycardia, hypotension, wheezing, GI effects, weight gain, depression, fatigue, sexual dysfunction

A

beta-adrenergic blockers

34
Q

dilate peripheral and coronary arteries and collateral vessels

A

short-acting nitrates

35
Q

decreased LDL (2)

A

statins
bile acid sequestrants

36
Q

SL NTG gives relief in __ minutes and lasts _____ minutes

A

5, 30-40

37
Q

side effects include fatigue, headache, dizziness, flushing, peripheral edema

A

calcium channel blockers (CCBs)

38
Q

monitor this enzyme for myalgia

A

CK-MM

39
Q

inhibits synthesis of triglycerides

A

niacin

40
Q

inhibits synthesis of LDL

A

niacin

41
Q

vasodilation (4)

A

ACE inhibitors
angiotensin receptor blockers
calcium channel blockers
nitrates

42
Q

contraindicated in patients with severe bradycardia and acute decompensated heart failure

A

beta-adrenergic blockers

43
Q

monitor when using digoxin

A

calcium channel blockers (CCBs)

44
Q

most potent statin

A

rosuvastatin (Crestor)

45
Q

used when inadequate response to other antianginal drugs

A

sodium current inhibitor

46
Q

these two drugs are used with UA and NSTEMI

A

heparin
glycoprotein IIb/IIIa inhibitors (before or during PCI)

47
Q

two serious adverse effects of rosuvastatin

A

liver damage, myalgia

48
Q

used with diet therapy and maximum statins

A

PCSK9 inhibitors

49
Q

cautious use of this medication with asthma and diabetes

A

beta-adrenergic blockers

50
Q

decreased triglycerides

A

fibric acid derivatives