chapter 5- the integumentary system Flashcards
integumentary system
Covers entires outer surface of the body
Includes skin, hair, nails, various glands, and sensory receptors
Most visible organ of the body
Failing liver- skin turning yellow
Heart failure- pink\light red colour (blood is not being pumped efficiently)
skin
Is the largest organ of the body by surface area (22 square feet) and weight (7% of average body weight)
what are the functions of skin?
Protects the body against:
- dehydration (keratin layer)
- impact and friction injuries
- mold and bacterial invasion
- UV light damage (melanin production)
- Acts as a receptor organ for sensory input
- some sensors are sensitive to temp, touch,
- Regulates body temp (capillary network and sweat glands)
- capillary networks are found near the surface of the skin.
- Secrets some wastes —> urea, salts and water
- Synthesizes vitamin D from cholesterol molecules under action of sunlight
- vit. D helps to absorb calcium. Which is needed for muscle contraction, nerve impulse
structures of the skin
epidermis and dermis
epidermis
outer, thinner layer
dermis
inner, thicker layer
- vascularized (has direct blood flow)
subcutaneous layer
The subcutaneous layer is NOT part of the skin.
also called hypodermis
Located underneath the dermis
epidermis - detailed
composed of keratinized stratified squamous epithelium
Squamous epithelium: flattened irregular shaped cell (looks like a “fried egg”)
Stratified: multiple layers
Keratinized: made up of dead cells that help to protect the living cells underneath
Contains four major types of cells and five cell layers
Epidermis is renewed every 30 to 40 days
Basal cells: basal meaning bottom layer. They are constantly diving by mitosis. Constantly creating new cells.
keratinocytes (90%)- epidermal cell type
produce keratin (fibrous protein) useful for protection
Protect skin and underlying tissues from heat, microbes and chemicals
Also produce lamellar granules: lipid rich secretion, fills spaces around and coats the same. Acts like a waterproofing agent. Helps to make sure we don’t lose water.
Surface cells die and only contain keratin (you can see)
melanocytes (8%)- epidermal cell type
spider-shaped epithelial cells
Secrete and transfer the pigment melanin to keratinocytes
Found near basal surface and their cell projections extend between keratinocytes
langerhas cells (or dendritic cells)- epidermal cell type
rise from red bone marrow and migrate to epidermis
Involved in immune responses
Merkel cells (or tactile epithelial cells) - epidermal cell types
least numerous
Contact sensory neurons and function in touch sensations
Loaded deep in epidermis
epidermal cell layers
Sole of feet, palms of hands thick skin have 5 layers, thin skin like on eyelids have 4 layers
stratum basale
deepest layer, attached to dermis by wavy border
Single row of cuboidal/columnar keratinocytes
cuboidal cells look like a cube. Columnar cells look like a column.
Cells divide by mitosis
Contains melanocytes and Merkel cells
stratum spinosum
8 to 10 layers of irregular-shaped keratinocytes
Cells contain many keratin filaments
Contains langerhans cells and projections of melanocytes (“spider arms”)
The cells are attached to one another very strongly.
stratum granulosum
3 to 5 layers of flattened keratinocytes; nucleus and organelles disintegrate
Cells contain kerayphyalin (protein) and lamellar granules
Lamellar graniles release a lipid-rich, water repellent secretion
Transition layer between living cells below and dead cells above
stratum lucidum
present only in thick skin (fingertips, palm and soles)
Consists of 3-5 layers of clear, flat, dead keratinocytes
Clear because they don’t have any organelles in them.
stratum corner
25 to 30 layers of flat, dead keratinocytes containing keratin
Lamellar secretion (lipids) between the cells waterproofs this layer