Chapter 5 - The Integumentary System Flashcards
The skin consists of two parts:
Epidermis and dermis
Outermost superficial region of the skin
Epidermis
Middle region of the skin
Dermis
Deepest region; subcutaneous layer to the skin (not technically part of the skin)
Hypodermis
The epidermis is composed of ______ ______ ______ _______, consisting of four distinct cell types and 4 or 5 layers
Keratinized stratified squamous epithelium
Cell types of the epidermis:
Keratinocytes, melanocytes, Markell cells, and Langerhans’ cells
Keratinocyte
Produce fibrous protein keratin
10-25% of cells in lower epidermis and produce pigment melanin
Melanocytes
Macrophages that help activate immune system
Langerhans cells (epidermal dendritic)
Touch receptors
Tactile (Merkel) cells
Layers of the epidermis:
Stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, stratum corneum
Deepest epidermal layer firmly attached to the dermis; single cell layer called stratum germinativum: cells undergo rapid division.
Single row of stem cells, melanocytes, merkel cells
Stratum basale
Multiple layers; keratinocytes abundant melanin granules dendritic or langerhans’ cells
Stratum spinosum
Thin; three to five cell layers in which the cells flatten; keratinocytes keratohyaline and lamellated granules accumulated
Stratum granulosum
A few rows of flat cells, thin transparent band superficial to the stratum granulosum. Only in thick skin - palms and soles. Dead keratinocytes
Stratum lucidum
20-30 rows of dead, flat cells. Three quarters of the epidermal thickness functions. Protects from abrasion and penetration. Waterproofs barrier against biological, chemical, and physical assaults. Dead keratinocytes - keratinized membranous sacs
Stratum corneum
- Strong, flexible connective tissue
- Cells include fibroblasts, macrophages, and occasionally mast cells and WBC
- Two layers: papillary and reticular
Dermis