Chapter 5 Osseous Tissue and Skeletal Structure Flashcards
What are The Functions of the Skeletal System?
- Blood cell production
- Leverage (tendons)
- Protection (heart, skull, brain, organs, spine)
Osseous Tissue
supporting connective tissue that converts to hydroxyapatite crystals - that resist compression
What makes up 1/3 of the the bone matrix?
Collagen Fibers
Which cells are the mature cells and are housed in the lacunae?
Osteocytes
What is a lamella?
Little plates and layers of and concentric circles of osteocytes
What are the channels that extend from the osteocytes to the bone capillaries?
cancaliculi
What are the Osteoblasts?
“building” cells - found in the inner and outer surfaces of bones. Responsible for osteogenesis.
What are Osteoprogenitor Cells?
Bone Stem Cells that will eventually differentiate into Ostoeoblasts. Heavily involved in repairing
They are found:
innermost layer of the periosteum
inner lining of the endosteum
Osteoclasts
“Kill” cells - that secrete acids, dissolving nearby bones. Causing the release of store calcium ions and phosphate ions in the blood
Osteolysis
The process of osteoclasts breaking down bones through the release of store calcium ions and phosphate ions in the blood.
What type of Lamellae are there?
Concentric - Circular
Interstitial - Filling the gaps between Osteons
Circumferential - Outer layer surrounding outside of the osteons.
Describe the structure of the long bone.
Epiphysis - the ends of the long bone
Diaphysis - the shaft
Metaphysis - at the joints of each ends
What is the Periosteum and what are the two layers of membrane called?
(around - Bone) a dense layer of connective tissue, enveloping the bones.
- Outermost Fiber Layer
- Innermost Osteogenic Layer (contains osteoprogenitor cells)
What form in the bones, that make up spongy bone?
Trabeculae
What is another name for Spongy bone?
Cancellous Bone
What are the strengths and weakness of Compact Bone?
Very strong when stress is conducted from one end of the bone to the other end.
Weak strength when stress is applied to the sides.
Describe the structure of Spongy bone?.
Trabeculae are oriented along the stress lines, with extensive cross-bracing.
What cells are found in the red bone marrow in the epiphysis?
Red Blood Cells and platelets
Where is yellow marrow found?
Medullary cavity
Endoesteum
Covers the spongy bones in the medullary cavity (consists of osteoprogenitor cells) actively involved in repair and growth
One cell layer and incomplete
What are the two types of Ossification and which bones do they involve in making?
Intramembranous Ossification (within mesanchymal cells) - Headbones and Clavicle
Endochondral Ossification (within cartilage) - Everything else
What are the steps of Intramembranous Ossification?
- DIFFERENTIATION OF OSTEOBLASTS FROM MESENCHYME
- Osteoblasts cluster to secrete components of matrix
- Osteoid then mineralized through crystallization of calcium salts forming the ossification center - FORMATION OF BONY SPICULES
- Osteoblasts differentiate into Osteocytes getting trapped into lacunae.
- The developing bone grows outward from the ossification center in small struts called spicules.
- Osteoblasts continue to be produced - ENTRAPMENT OF BLOOD VESSELS
- The rate of bone growth accelerates as blood vessels branch within and grow between spicules.
- Spicules interconnect and start to trap blood vessels within bone - FORMATION OF SPONGY BONE
- Bone continues to be deposited by osteoblasts.
- Bony plate is perforated by blood vessels.
- Adjacent bony plates fuse together
What is interstitial growth?
Growth in length
Appositional growth
Grown in diameter
What are the four major sets of blood vessels associated with the long bones?
Nutrient vessels (artery and vein)
Metaphyseal Vessels
Epiphyseal Vessels
Periosteal Vessels
What factors regulate bone growth?
Minerals Vitamins Calcitriol Hormones Sex Hormones
What vitamins and minerals are essential to bone growth?
(Calcium Can Make People Strong
along with
ACiD)
Calcium Ions Citrate Ions Magnesium ions Phosphate ions Sodium Ions
Vitamin A
Vitamin C
Vitamin D3 (Calcitriol)
What glands are involved in bone growth and what hormones do they release?
Parathyroid Gland - Parathyroid
Thyroid Gland - Thyroxine and Calcitonin
Pituitary Gland - Growth Hormone