Chapter 5 Microbial Metabolism Flashcards
collision thoery
how chemical reactions occur and how certain factors affect the rates of those reactions
factors include:
velocities of colliding parts
energy of colliding parts
specific chemical configurations
tuurnover number
maximum number of substrate molecules an enzyme molecule converts to product each second
apoenzyme
protein portion of an enzyme
cofactor
non protein portion of an enzyme
coenzyme
if the cofactor is an organic molecule
holoenzyme
the apoenzyme and cofactor together
NAD NADP
coenzymes that are derivatives of B vitamin niacin
function as electron carriers
NAD anabolic
NADP catabolic
FMN FAD
coenzymes that are derivatives of B vitamin riboflavin function as electron carriers
CoA
derivative of B vitamin pantothenic acid
important role in synthesis and breakdown of fats in Krebs cycle
competative inhibitors
fill active site of an enzyme and compete with the normal substrate for the active site
its shape and chemical structure are similar to specific substrate
noncompetitive inhibiitors
do not compete for active site, interact with another part of the enzyme
allosteric inhibition
inhibitor binds to a site on the the enzyme other than active site (called allosteric site)
oxidation
loss of electrons from atom or molecule, produces energy
reduction
atom or molecule has gained electrons
substrate level phoshorylation
ATP is usually generated when a high energy P is directly transferred from a phosphorylated compound to ADP