Chapter 5 Integumentary System Flashcards
Functions of the Integumentary a System
- External protective covering
- Barrier to viruses and bacteria
- Regulation of body temperature
- Reduces dehydration
- Facilitates cutaneous sensation
- Maintain metabolic functions and blood reservoirs
What makes up the integumentary system?
Skin
Hair
Nails
Sweat and Oil Glands
The 2 Regions of the skin, and details:
- Epidermis: outermost protective shield of the body. Composed of epithelial cells. Not vascularized.
- Dermis: Makes up the bulk of the skin. Tough and leathery layer composed mostly of fibrous tissue. Vascularized.
Hypodermis (Superficial Fascia)
Subcutaneous layer deep to the two layers of skin. Composed mostly of adipose tissue. Mainly insulates, and anchors skin to underlying structures, but also helps protect the underlying organs.
The 4 Cells of the Epidermis:
1) Keratinocytes
2) Melanocytes
3) Dendritic(Langerhans Cells)
4) Tactile (Merkel) Cells
Cells of epidermis: #1 Keratinocytes
- Produce keratin, which helps give epidermis protective qualities.
- Connected by desmosomes.
- Surface for Stratum Basale
- Epidermal growth factor
- Keratin-filled plasma membranes that die and flake off at the skin’s surface
Cells of the epidermis: #2 Melanocytes
- Located in deepest layer of epidermis; stratum Basale.
- Spider-shaped, epithelial cells.
- Synthesize the pigment Melanin.
- Melanin accumulates at superficial site of cells, eventually reaching surface of the skin to protect against UV Radiation.
Cells of Epidermis: #3 Dendritic (Langerhans) Cells
- Surface from bone marrow and migrate to epidermis.
- Activators of the Immune System
- Ingest foreign substances
- Extend among surrounding keratinocytes to form a continuous network
Cells of the Epidermis: #4Tactile (Merkel) Cells
- Located in epidermal-dermal junction.
- Shaped like a spiked hemisphere
- Intimately associated with disc-like sensory nerve endings.
- Function as sensory receptors for touch.
The 5 Layers of the Epidermis:
Deep to Superficial
1) Stratum Basale
2) Stratum Spinosum
3) Stratum Granulosum
4) Stratum Corneum
5) Stratum Lucidium(only in palms of hands and soles of feet)
Layers of the Epidermis: #1 Stratum Basale
- Deepest Epidermal layer
- One row of actively mitotic stem cells
- Newly formed cells become part of the more superficial layers.
- See occasional melanocytes and dendritic cells.
Layers of the Epidermis: #2 Stratum Spinosum
- Several layers of keratinocytes unified by desmosomes.
- Cells contain thick bundles of intermediate filaments made of pre-keratin.
Layers of the Epidermis: #3 Stratum Granulosum
- Typically five layers of flattened cells, organelles deteriorating.
- It’s cytoplasm is full of lamellar granules (release lipids) and keratohyaline granules.
Layers of the Epidermis: #4 Stratum Corneum
- Most superficial layer.
- 20-30 layers of dead cells; flat membrane sacs filled with keratin.
- Some glycolipids in extra cellular space.
Layers of the Epidermis: #5 Stratum Lucidum
- ONLY IN THICK SKIN OF PALMS OF HANDS AND SOLES OF FEET
- Consists of 2-3 rows of dead keratinocytes
Define Apoptosis
- Occurs from stratum Basale all the way to stratum Corneum
- The cells break down, flatten, thicken, and shed away.
- No nucleus or organelles by the end of this process!
The 2 Layers of the Dermis:
- Papillary
- Reticular
2 Layers of the Dermis: #1 Papillary Layer
- Loosely woven aveolar tissue with collagen, elastic fibers, and blood vessels.
- Allows certain things to pass through while keeping harmful foreign products from entering.
Parts and Examples of the Papillary Layer:
Dermal Papillae: Many contain capillary loops while others house free nerve endings.
Epidermal Ridges: FINGERPRINTS! Also called Friction Ridges.
Two layers of the Dermis: #2 Reticular Layer
- 80% of the dermis.
- Coarse, irregular, dense fibrous tissue.
- Contains thick bundles of interlacing collagen fibers.
Example: Cleavage Lines- externally invisible lines that run longitudinally. Very important for surgeons when performing incisions.