Chapter 13: The PNS and Reflexes Flashcards
Sensory Receptors:
Specialized to respond to changes in the environment called Stimuli.
What Sensory Receptors are Classified by:
o 1) Type of Stimulus they detect
o 2) Body Location
o 3) Structural Complexity
Classification of Sensory Receptors by Stimulus Type:
Mechanoreceptors
Respond to mechanical force such as touch, pressure, vibration, and stretch.
Classification of Sensory Receptors by Stimulus Type:
Thermoreceptors
Respond to temperature changes.
Classification of Sensory Receptors by Stimulus Type:
Photoreceptors
Such as those of the retina of the eye, respond to light.
Classification of Sensory Receptors by Stimulus Type:
Chemoreceptors
Respond to chemicals in solution.
Classification of Sensory Receptors by Stimulus Type:
Nociceptors
Respond to potentially damaging stimuli that result in pain.
Classification of Sensory Receptors by Location:
Exteroceptors
o Sensitive to stimuli arising outside the body.
o Most are near the body’s surface.
o Include touch, pressure, pain, and temperature receptors in the skin and most receptors of special senses.
Classification of Sensory Receptors by Location:
Interoceptors
o Called visceroceptors.
o Respond to stimuli within the body.
o Monitor a variety of stimuli including chemical changes, tissue stretch, and temperature.
o Can cause pain, discomfort, hunger, or thirst. But we are usually unaware of their workings.
Classification of Sensory Receptors by Location:
Proprioceptors
o Respond to internal stimuli.
o Their location is much more restricted than interoceptors.
o Occur in skeletal muscles, tendons, joints, and ligaments and in connective tissue coverings of bones and muscles.
o Constantly advise the brain of our body movements by monitoring how much our organs containing these receptors are stretched.
The 2 Classifications of Receptors by Structure:
o Nonencapsulated (Free) o Encapsulated
Types and Aspects of Nonencapsulated (Free) Receptors:
o Present nearly everywhere in the body, abundant in epithelia and connective tissues.
o Mostly Nonmyelinated, small diameter C-fibers whose distal endings usually have small knoblike swellings.
o Respond chiefly to temperature and painful stimuli, but some respond to tissue movement and pressure as well.
o A key player in detecting painful stimulus is a plasma protein called the vanilloid receptor. Opened by heat, low Ph, and various chemicals.
o Also deals with the itch sensation. The itch receptor has a very thin diameter. Number of chemicals are present in inflamed sites and active these nerve endings.
Other Types of Nonencapsulated (Free) Receptors:
Tactile (Merkel) Discs
- Lie in deepest layer of the epidermis.
- Function as light touch receptors.
- Certain free nerve endings associate with enlarged, disc-shaped epidermal cells to form tactile discs.
Other Types of Nonencapsulated (Free) Receptors:
Hair Follicle Receptors
- Free nerve endings that wrap around hair follicles.
- Light touch receptors that detect bending of hairs.
Encapsulated Receptors:
o Consist of one or more fiber terminals of sensory neurons enclosed in connective tissue capsule.
o Virtually all are mechanoreceptors, but vary in shape, size, and distribution in the body.
Types of Encapsulated Receptors:
Tactile Corpuscles
o Also Called Meissner’s Corpuscles.
o Small receptors with sensory terminals surrounded by Schwann Cells and a thin egg-shaped connective tissue capsule.
o Found just beneath the epidermis in the dermal papillae and are especially numerous in sensitive, hairless skin areas.
o Receptors for discriminative touch, and play a role in sensing light touch in hairless skin.
Types of Encapsulated Receptors:
Lamellar Corpuscles
o Also called Pacinian corpuscles
o Scattered deep in the dermis, and in subcutaneous tissue underlying the skin.
o Mechanoreceptors stimulated by deep pressure, but respond only when pressure is first applied, and thus are better for monitoring vibration.
o Largest Corpuscle receptors.
o Single Dendrite surrounded by a capsule containing up to 60 layers of collagen fibers and flattened supportive cells.
Types of Encapsulated Receptors:
Bulbous Corpuscles
o Also called Ruffini endings.
o Lie in the deris, subcutaneous tissue, and joint capsules.
o Contain receptor endings enclosed by a flattened capsule.
o Respond to deep and continuous tissues.
Types of Encapsulated Receptors:
Muscle Spindles
o Fusiform proprioceptors found throughout the perimysium of a skeletal muscle.
o Each spindle consists of a bundle of modified skeletal fibers (intrafusal fibers) enclosed in a connective tissue capsule.
o Spindles detect muscle stretch and initiate a reflex that resists the stretch.
Types of Encapsulated Receptors:
Tendon Organs
o Proprioceptors located in tendons close to skeletal muscle insertion.
o Consist of small bundles of tendon fibers enclosed in layered capsule with sensory terminals coiling between and around the fibers.
o Muscle contraction stretches the tendon fibers, resulting in compression of the nerve fibers that activates the tendon organs. A reflex is initiated that causes contracting muscles to relax.
Types of Encapsulated Receptors:
Joint Kinesthetic Receptors
o Proprioceptors that monitor stretch in the articular capsules that enclose synovial joints.
o Receptor category contains four receptor types: Lamellar corpuscles, bulbous corpuscles, free nerve endings, and receptors resembling tendon organs.
o Together the receptors provide info. on joint position and motion.
Sensation:
Awareness of changes in the internal and external environments.
Perception:
Conscious interpretation of those stimuli.
The Somatosensory System:
- The part of the sensory system serving the body walls and limbs.
- Receives input from exteroceptors, proprioceptors, and interoceptors.
The 3 Main Levels of Neural Integration in the Somatosensory System:
o Receptor Level: Sensory receptors.
o Circuit Level: Processing in ascending pathways.
o Perceptual Level: Processing in cortical sensory areas.
For Processing at the Receptor Level to Occur These Things Must Happen:
o Stimulus energy must match the specificity of the receptor.
o Stimulus must be applied within a sensory receptor’s receptive field. The smaller the receptive field the greater the ability of the brain to accurately localize the stimulus site.
o Stimulus energy must be converted into the energy of a graded potential, this process is called Transduction. One of two types of Graded potential can be produced at the receptor level: 1) Generator Potential: When the receptor region is part of a sensory neuron. 2) Receptor Potential: When the receptor is a separate cell. The amount of NT release is changed.
o Graded-potentials in the first-order sensory neuron must reach threshold so that voltage-gated sodium channels on the axon are opened and nerve impulses are generated and propagated to the CNS.
Adaptation:
A change in sensitivity in the presence of a constant stimulus.
Phasic Receptors:
- Fast-adapting.
- Five bursts of impulses at the beginning and the end of the stimulus.
- Report changes in the internal and external environment.
Tonic Receptors:
- Provide a sustained response and never adapt.
- Nociceptors and Proprioceptors fit into this category.
Processing at the Circuit Level:
-Main objective for this level is to deliver impulses to the appropriate region of the cerebral cortex for localization and perception of the stimulus.
Processing at the Perceptual Level:
o At this level sensory input it interpreted in the cerebral cortex.
o Ability to identify and appreciate sensations depends on location of the target neurons in the sensory cortex, not on the nature of the message.
o The brain always interprets the activity of a specific sensory receptor as a specific sensation, no matter how it’s activated.
Perceptual Detection:
- The ability to detect that a stimulus has occurred.
- Simplest level of perception.
- Inputs from several receptors must be summed for perceptual detection to occur.
Magnitude Estimation:
- The ability to detect how intense the stimulus is.
- Perceived intensity increases as stimulus intensity increases because of frequency coding.
Spatial Discrimination:
- Allows us to identify the site or pattern of stimulation.
- Common tool for studying this quality is the two-point discrimination test which determines how close together two points on the skin can be and still be perceived as two points rather than as one.
Feature Abstraction:
- The mechanism by which a neuron or circuit is tuned to one feature, or property, of a stimulus in preference to others.
- Sensation usually involves an interplay of several stimulus features.
Quality Discrimination:
- The ability to differentiate the submodalities of a particular sensation.
- Each sensory modality has several qualities, or submodalities.
Pattern Recognition:
The ability to take in the scene around us and recognize a familiar patter, an unfamiliar one, or one that has special significance for us.
Perception of pain:
o Pain receptors activated by extremes of pressure, temperature, and a group of chemicals released from injured tissue.
o Sharp pain carried by smallest of myelinated sensory fibers, group A delta fibers. While the pain is carried slower than small nonmyelinated group C fibers both release the NTs glutamate and substance P, and activate second-order sensory neurons.
Pain Tolerance:
o Everybody has the same pain threshold, meaning we all perceive pain at roughly the same stimulus intensity. BUT we all have different tolerances to pain.
o Genes help determine a person’s pain tolerance and response to pain medications.
Hyperalgesia:
Pain amplification.
Phantom Limb Pain:
When somebody feels pain in a limb that is no longer present.
Visceral Pain:
- Results from noxious stimulation of receptors in the organs of the thorax and abdominal cavity.
- Dull aching, gnawing or burning in the deep tissue of the body.
Referred Pain:
Pain stimuli arising in one part of the body are perceived as coming from another part.
Nerves and the 3 Successive Wrappings of Nerves:
A cordlike organ that’s part of the peripheral nervous system. Vary in size but all consist of bundles of peripheral axons.
o Endoneurium: Delicate layer of loose connective tissue that also encloses the fiber’s associated Schwann cells.
o Perineurium: Coarser connective tissue wrapping, binds groups of fibers into fascicles.
o Epineurium: Encloses all fascicles to form the nerve.
Classifications of Nerves Based on the Direction they Transmit Impulses:
o Mixed Nerves: Contain both sensory and motor fibers and transmit impulses both to and from the CNS. Most nerves are in this category.
o Sensory (Afferent) Nerves: Carry impulses only toward the CNS.
o Motor (Efferent) Nerves: Carry impulses only away from the CNS.