Chapter 5 - Epidermal Growths Flashcards
neoplasms of the epidermis are derived from a proliferation of ___ or ____
basal cells or keratinocytes
epidermal growths are recognized clinically by a localized thickening of the epidermis that often is accompanied by thickening of the stratum _____, which is called hyperkeratosis or scale
corneum
large, indurated, rapidly growing, crusted or ulcerated tumors suggest a ____ process and should undergo a biopsy
malignant
benign neoplasms caused by infection of epidermal cells with papillomaviruses
wart
thickening of the epidermis with scaling and an upward extension of the _____ containing prominent capillaries give warts their “warty” or verrucous appearance
dermal papillae
most common sexually transmitted disease
HPV
what type of occupations have a higher incidence of common warts?
butchers and meat cutters
EWWW
___ affect sexually active individuals, and their occurrence in children should raise suspicions of sexual abuse
Anogential warts (condylomata acuminata)
Call stabler and bension
flesh colored firm papule or nodule that has a corrugated or hyperkeratotic surface, interrupts the normal skin lines and is studded with black puncta, linear fashion from autoinoculation
common wart or verrua vulgaris
__ variant of verrucca vulagaris occurs on the head and neck
filiform
subtle appearance, flesh colored or reddish brown, slightly raised, flat surfaced 2-5 mm, well marginated papulae
flat wart
a single, painful papule on the plantar aspect of the foot, covered by a thick callus
plantar wart
__ involves the rectum, perineal region, inguinal folds, external genitalia and occasionally urethra and vagina, soft moist papule and plaque that may be sessile or pedunculated
condyloma acuminatum - venereal wart
soaking the genital area for 5 minutes with 3-5% ____ causes warts to turn white
acetic acid
Diff Diagnosis of a wart
Callus Squamous cell carcinoma Comedo lichen planus corns Secondary syphilis Seborrheic keratoses Bowenoid papulosis
an uncommon disorder characterized by erythematous, sometimes pigmented, papulae occuring in the genital region of sexually active young adults
bowenoid papulosis
treatment for warts
cryotherapy with liquid nitrogen
electrodesiccation and curettage
surgical excision
laser therapy
most common initial mode of treatment, uses either a cotton tipped stick or a cryospray unit for application of the liquid nitrogen onto the verrua
cryotherapy with liquid nitrogen
a potent blistering agent derived from the blister beetle, an alternative office treatment that is applied to common warts and covered with tape
Cantharidin
cytotoxic agent that resulted in renal toxicity, polyneuritis, and shock
podophyillin
a chemically pure ligand derived from podophyillin is available as topical solution or gel, for patient self treatment of external genital warts
Podofilox
t/f warts are contagious
True
if they weren’t, sexual partners wouldn’t share them and the book says some guy in the 1800s Jadassohn inoculated normal skin with wart material and warts grew about 2- 3 months after
a localized thickening of epidermis secondary to chronic pressure or friction
corn (clavus or heloma)