Chapter 5 - Epidermal Growths Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

neoplasms of the epidermis are derived from a proliferation of ___ or ____

A

basal cells or keratinocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

epidermal growths are recognized clinically by a localized thickening of the epidermis that often is accompanied by thickening of the stratum _____, which is called hyperkeratosis or scale

A

corneum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

large, indurated, rapidly growing, crusted or ulcerated tumors suggest a ____ process and should undergo a biopsy

A

malignant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

benign neoplasms caused by infection of epidermal cells with papillomaviruses

A

wart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

thickening of the epidermis with scaling and an upward extension of the _____ containing prominent capillaries give warts their “warty” or verrucous appearance

A

dermal papillae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

most common sexually transmitted disease

A

HPV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what type of occupations have a higher incidence of common warts?

A

butchers and meat cutters

EWWW

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

___ affect sexually active individuals, and their occurrence in children should raise suspicions of sexual abuse

A

Anogential warts (condylomata acuminata)

Call stabler and bension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

flesh colored firm papule or nodule that has a corrugated or hyperkeratotic surface, interrupts the normal skin lines and is studded with black puncta, linear fashion from autoinoculation

A

common wart or verrua vulgaris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

__ variant of verrucca vulagaris occurs on the head and neck

A

filiform

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

subtle appearance, flesh colored or reddish brown, slightly raised, flat surfaced 2-5 mm, well marginated papulae

A

flat wart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

a single, painful papule on the plantar aspect of the foot, covered by a thick callus

A

plantar wart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

__ involves the rectum, perineal region, inguinal folds, external genitalia and occasionally urethra and vagina, soft moist papule and plaque that may be sessile or pedunculated

A

condyloma acuminatum - venereal wart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

soaking the genital area for 5 minutes with 3-5% ____ causes warts to turn white

A

acetic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Diff Diagnosis of a wart

A
Callus 
Squamous cell carcinoma
Comedo
lichen planus
corns
Secondary syphilis
Seborrheic keratoses
Bowenoid papulosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

an uncommon disorder characterized by erythematous, sometimes pigmented, papulae occuring in the genital region of sexually active young adults

A

bowenoid papulosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

treatment for warts

A

cryotherapy with liquid nitrogen
electrodesiccation and curettage
surgical excision
laser therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

most common initial mode of treatment, uses either a cotton tipped stick or a cryospray unit for application of the liquid nitrogen onto the verrua

A

cryotherapy with liquid nitrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

a potent blistering agent derived from the blister beetle, an alternative office treatment that is applied to common warts and covered with tape

A

Cantharidin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

cytotoxic agent that resulted in renal toxicity, polyneuritis, and shock

A

podophyillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

a chemically pure ligand derived from podophyillin is available as topical solution or gel, for patient self treatment of external genital warts

A

Podofilox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

t/f warts are contagious

A

True

if they weren’t, sexual partners wouldn’t share them and the book says some guy in the 1800s Jadassohn inoculated normal skin with wart material and warts grew about 2- 3 months after

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

a localized thickening of epidermis secondary to chronic pressure or friction

A

corn (clavus or heloma)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

white gray or yellow brown, well circumscribed, horny papules or nodules

A

corn

25
Q

diff dx of a corn

A

plantar wart - if skin lines are present its a corn

26
Q

tx for a corn

A

paring down with scalpel, mediplast or reduction of trauma (new shoes) or surgery (correction of deformity)

27
Q

a __ will persist unless friction and pressure are relieved.

A

corn

28
Q

a benign neoplasms of epidermal cells that clinically appears as a scaling, “pasted on” papule or plaque, autosomal dominant inherited trait

A

seborrheic keratosis

29
Q

vary is size from 2mm to 2cm and slightly to markedly elevated, color ranges from flesh to tan/brown and occasionally black, oval to round, greasy appearing, sharply marginated growths

A

seborrheic keratosis

30
Q

diff dx of seborrheic keratosis

A

wart, actinic keratosis, nevus, pigmented basal cell carcinoma, malignant melanoma

31
Q

what type of biopsy confirms the clinical impression of seborrheic keratosis?

A

excisional or shaved

32
Q

leser-trelat, the rapid increase in size and number of seborrheic keratoses is accompanied by _____

A

pruritus

33
Q

acrochordon is another name for ___

A

skin tag

34
Q

a benign fleshy tumor that is frequently acquired in adult life, slightly hyperplastic epithelium covering a dermal connective tissue stalk, pedunculated, flesh colored growth

A

skin tag

35
Q

soft, tan to flesh colored, 1-10 mm, pedunculated, fleshy papule, has a smooth or folded surface and frequently appears boggy of filiform

A

skin tag

36
Q

t/f large or necrotic skin tags should be sent to pathology

A

true!

purple box on page 59!

37
Q

caused by a DNA poxvirus that infects epidermal cells, lesions appear smooth, dome-shaped papules that often are umbilicated

A

molluscum contagiosum

38
Q

papules are 2-5 mm wide, hard, smooth, dome shaped and flesh colored or translucent, central umbilication from which a cheesy core can be expressed, singly or in groups

A

molluscum contagiosum

39
Q

precancerous neoplasm of the epidermis caused by the UV portion of sunlight

A

actinic keratosis

40
Q

1-10 mm, reddish, ill-marginated patches and papules that have a rough, yellowish brown, adherent scale

A

actinic keratosis

41
Q

a malignant neoplasm of keratinocytes, locally invasive and has the potential to metastasize, scaling, indurated plaque or nodule that sometimes bleeds or ulcerates

A

squamous cell carcinoma

42
Q

second most common skin cancer

A

squamous cell carcinoma

43
Q

chronic, nonhealing, bleeding growth or ulcer should arouse suspicion of ___

A

squamous cell carcinoma

44
Q

squamous cell carcinoma in situ of the skin, erythematous, scaling, crusted, well marginated patch

A

Bowen’s disease

45
Q

Squamous cell carcinoma is situ of the glans penis is referred to as ___ , red, velvety, moist patch

A

erythroplasia of Queyrat

46
Q

rapidly growing neoplasma of the epithelium that is biologically benign but histologically resembles a squamous cell carcinoma, round, flesh colored nodule that characteristically grows rapidly (within 4-6 weeks) and has a central keratin filled crater

A

Keratoacanthoma

47
Q

Exposure to what carcinogens leads to squamous cell carcinoma?

A

arsenic and soot, UV, X-irradiation, and viruses

48
Q

a rare genetic disorder, develop hundreds of flat warts caused by HPV and prone to transform into squamous cell carcinoma

A

epidermodysplasia verruciformis

49
Q

a malignant neoplasm arising from the basal cells of the epidermis, rarely metastasize, types include: nodular, pigmented, superficial and scarring

A

basal cell carcinoma

50
Q

most common human malignant disease

A

basal cell carcinoma

51
Q

which TYPE of basal cell carcinoma is most common?

A

nodular, has a pearly, semitranslucent papule or nodule that often has a central depression or crater, telangiectasia and a rolled waxy border.

52
Q

a shiny, blue-black papule, nodule or plaque, which type of basal cell is this?

A

pigmented basal cell carcinoma

53
Q

type of basal cell carcinoma that occurs on the thorax, red, slightly scaling, well demarcated, eczematous appearing patch, may become slightly eroded and crusted, subsequently leaving an atrophic, slightly depressed center

A

superficial basal cell carcinoma

54
Q

atrophic, white, slightly eroded or crusted plaque that often looks like a scar

A

scarring basal cell carcinoma

55
Q

rare malignant tumor that usually occurs as a solitary nodule on the head and neck of elderly patients

A

merkel cell carcinoma

56
Q

treatment of ___ includes local excision, sentinel lymph node biopsy and radiotherapy

A

merkel cell carcinoma

57
Q

hamartoma of the sebaceous glands and other cutaneous structures appears at birth as a thin yellowish plaque with alopecia

A

nevus sebaceus

58
Q

plaque becomes verrucous and both benign and malignant tumors may develop, excision is recommended, may be associated with neurologic or skeletal abnormalities

A

nevus sebaceus

59
Q

benign tumor of the hair follicle, solidary or multiple firm, smooth, flesh-colored papules or nodules, inherited as an autosomal dominant condition

A

trichoepithelioma