Chapter 5: Embryological Tooth Development Flashcards

1
Q

When does primary dentition begin to develop?

A

6th week of intrauterine life

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2
Q

What affects teeth formation?

A

Risk behaviours such as: tobacco, alcohol, drugs

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3
Q

What causes significant impact on the proper meshing of all pieces?

A

Any change in calcification, chronology, or eruption sequence

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4
Q

What are the causes of malocclusion?

A

General, endocrine, genetic factors, cysts, and number abnormalities

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5
Q

What’s responsible for the development of the face and when is it clearly distinguishable?

A

Primary or primitive processes
4th week of pregnancy

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6
Q

What is the stomodeum (primitive oral cavity) delimited by from the cranial position?

A

Frontonasal prominence which will lead to the lateral and medial nasal processes

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7
Q

What is the stomodeum (primitive oral cavity) delimited by from both sides?

A

Maxillary process

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8
Q

What is the stomodeum (primitive oral cavity) delimited by from the caudal position?

A

Mandibular process

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9
Q

What is the stomodeum (primitive oral cavity) delimited by in the frontal view?

A

Frontonasal prominence, nasal placode, maxillary process, and mandibular process

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10
Q

What is the stomodeum (primitive oral cavity) delimited by from the lateral view?

A

Buccopharyngeal membrane

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11
Q

What is the stomodeum separated from the pharynx from?

A

Buccopharyngeal membrane

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12
Q
  • the maxillary processes grow forward and join with the lateral nasal processes
  • the mandibular processes begin to merge into a single structure (mandibular depression is filled by the proliferation of mesenchyme)

These statements refer to which week?

A

5th week

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13
Q

What reduces the size of the mouth opening? And when does it happen?

A

When the maxillary and mandibular processes merge laterally to stomodeum
6th-7th week

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14
Q

The primitive palate derives from ?

A

The union and fusion of the medial nasal processes and the maxillary processes

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15
Q

When is the palatal triangle completed and what does it include?

A

During the 6th week
Includes:
The middle portion of the upper lip
Premaxilar area that will eventually give rise to the alveolar bone which will house the 4 upper incisors

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16
Q

The primary palate consists of a strong band of tissue with an ____ cover and a _____ interior ?

A

Ectodermal, mesenchymal

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17
Q

Place these statements in the order they occur:
A. Dental lamina form the teeth
B. Mesenchymal condensation
C. Vestibular lamina and dental lamina
D. Ectodermal cells proliferate into the mesenchymal tissue
E. Primary epithelial band

A

A. 5
B. 2
C. 4
D. 1
E. 3

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18
Q

What allows the separation between the lip and the future alveolar area?

A

The vestibular lamina (lip furrow)

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19
Q

Initial dental lamina= ___ teeth?

A

20

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20
Q

Where do the permanent teeth form from?

A

All except the permanent teeth form from extensions of the dental lamina

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21
Q

The secondary palate is formed from?

A

Formation of two palatal shelves on the maxillary prominences, elevation of these shelves to a horizontal position and fuse
The shelves also fuse anteriorly upon the primary palatal triangle with the nasal septum that grows downward

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22
Q

The incisive foramen is a ?

A

Vestige (remnant) of that fusion and is the landmark between the primary and secondary palate

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23
Q

What is the embryological process by which tooth buds form?

A

Odonto genesis

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24
Q

Teeth develop from 2 embryological tissues which are?

A

Ectoderm and mesoderm

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25
Q

Ectoderm forms?

A

Enamel and epithelium

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26
Q

Mesoderm forms?

A

Dentin, dental pulp, cement, and mesenchyme

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27
Q

5 periods of odontogenesis:

A

Initiation stage
Proliferation stage
Histodifferentiation stage
Morphodifferentation stage
Apposition/calcification stage

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28
Q

Initiation period is the ?

A

Bud stage and dental lamina

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29
Q

Proliferation period is the?

A

Cap stafe

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30
Q

Histodifferentiation period is the?

A

Early bud stage

31
Q

Morphodifferentiation period is the ?

A

Late bud stage

32
Q

Apposition/calcification period is the ?

A

Crown stage

33
Q

What are the ectoderm and mesoderm separated by?

A

Basement membrane

34
Q

Dental lamina—> initiation period:
- occurs at which week?
- what happens during?

A
  • 6th week
  • thickening of the epithelium that invaginates into the mesoderm by proliferation of the cells of the basal layer
  • the dental lamina forms—> tooth germ
35
Q

Bud stage—>initiation period:
- occurs at which week?
- what happens during?

A
  • 7th-9th week
  • cells multiply enter in the underlying connective tissue
  • 10 buds develop in each arch
36
Q

The buds of the permanent teeth, are formed from the? While the permanent molars are ?

A

the temporary buds

Permanent molars are independent buds.

37
Q

Fewer buds mean?

A

Agenesis

38
Q

Extra buds mean?

A

Supernumerary

39
Q
A
  • 9th-11th week
  • Epithelial cells proliferate resulting in the formation of tooth germ.
  • mesoderm produces the dental papilla which gives rise to the dentin and dental pulp.
  • The ectodermal covering the papilla is called the enamel organ since it will produce the future enamel of the tooth.
  • the mesenchyme condenses as the dental sac, which later forms the cement, periodontal ligament, and alveolar bone.
  • In this period we distinguish the 3 formative elements of the tooth
40
Q

The 3 formative elements of the tooth are?

A

Enamel organ or dental organ: enamel.
Dental papilla: dentin and dental pulp.
Dental sac: cement, PDL, and alveolar bone.

41
Q

4 layers of the enamel organ are?

A
  • IEE
  • OEE
  • Stellate reticulum
  • intermediate reticulum
42
Q

Shape of OEE? And location?

A

Cuboidal
In contact with dental sac

43
Q

Which cells are capable of developing into ameloblasts (that produce enamel)?

A

IEE

44
Q

Location of IEE?

A

In contact with dental papilla

45
Q

Shape of stellate reticulum? Location?

A

Polymorphic, between IEE and OEE

46
Q

Shape of intermediate reticulum? Function?

A

Squamous
Help ameloblasts produce enamel

47
Q

Excess initiation and proliferation of thickening, bud, and cap stage causes?

A

Cysts, odontomas, supernumeraries

48
Q

Defect in initiation and proliferation of thickening, bud, and cap stage causes?

A

Agenesis, oligodontia/anodontia

49
Q

Early bell stage—> histodifferentaion period:
- occurs at which week?
- what happens during?

A
  • 14th week
  • Tooth germ cells begin to specialise.
  • The tissue inside this bell is the dental papilla.
  • The Internal dental epithelium will form the enamel.
  • The condensation of the mesodermal tissue will have created the dental sac that will give rise to the cement and the periodontal ligament.
  • The enamel organ is still attached to the oral epithelium by the enamel cord (joins the tooth germ to the maxillary epithelium).
  • An extension begins to form —> dental lamina of the permanent tooth
50
Q

Function of the OEE?

A

Protection

51
Q

Function of the IEE?

A

Enamel formation

52
Q

Function of the intermediate reticulum?

A

Nutrition of the IEE

53
Q

Function of the stellate reticulum?

A

Protection and nutrition

54
Q

Where is the dental lamina of the permanent tooth located ?

A

lingually and distally to the primary tooth

55
Q

What’sthe cause of enamel or dentin structure anomalies?

A

The disorders of endogenous or exogenous origin that alter the differentiation of the cells that form the dental germ

56
Q

Late bell stage—> morphodifferentiation period:
- occurs at which week?
- what happens during?

A

18th week
- The dental germ is independent of the oral epithelium. (Because the enamel cord disintegrated).
- The four layers of the enamel organ are fully differentiated and at the site of the neck of the
future tooth, internal and external epithelium form a vertical handle from which it derives the
tooth root.
- The ectomesenchymal cells of the dental papilla closest to the IEE are differentiated into odontoblasts, that are in charge of the dentin development.
- Cells from the IEE closest to the stellate reticulum (preameloblasts) differentiate into ameloblasts to form enamel
- Simultaneously with this process the central part of the dental papilla will become the pulp.

57
Q

Enamel forms first in? Then in?

A

first in the future incisal edges and later in the
future cervical edge

58
Q

This double cell layer composed by ameloblasts and odontoblasts is named

A

amelo-dentine or bilaminar membrane

59
Q

The anomalies suffered by the dental germ during its morphological differentiation, will result in teeth of

A

abnormal shape and/or size

60
Q

Any systemic or local disturbance that damages the ameloblasts during the enamel formation
phase can cause an

A

interruption of the apposition of the matrix, resulting in a hypoplasia of the enamel

61
Q

Crown stage—> calcification period:

A
  • The calcification starts in the areas that will later correspond to the cusp tip and the incisal edge, followed by concentric layers in different areas.
62
Q

When is the crown morphology established before or after the apposition and mineralisation?

A

before the apposition and mineralization of the dental tissues begin.

63
Q

Calcification is?

A

precipitation of mineral salts mainly calcium and phosphorus on the previously developed tissue matrix. It consists of layered appositional growth

64
Q

The enamel of what region will be the last to be formed?

A

cervical region

65
Q

Temporary teeth: intrauterine:
• CI: ? week.
• LI: ? week.
• 1st molar: ? week.
• C: ? week.
• 2nd molar: ? week.
• Apical closure takes place between the ? year after the eruption.

A

• CI: 14 week.
• LI: 16 week.
• 1st molar: 15.5 week.
• C: 17 week.
• 2nd molar: 18 week.
• Apical closure takes place between the 1-1.5 year after the eruption.

66
Q
  • Permanent teeth: postnatal:
    • 1st molar: ?
    • Central incisor, lower lateral incisor: ?
    • Upper lateral incisor: ? year old.
    • 1st premolars: ? years old.
    • 2nd premolar: ? years old, the lowers sometimes up to ? years old.
    • The apical closure of permanent teeth occur about ? and a half years after it’s eruption.
A
  • Permanent teeth: postnatal:
    • 1st molar: at birth time
    • Central incisor, lower lateral incisor: first months of life
    • Upper lateral incisor: 1 year old.
    • 1st premolars: 2 years old.
    • 2nd premolar: 2.5 years old, the lowers sometimes up to 4-5 years old.
    • The apical closure of permanent teeth occur about 3 and a half years after it’s eruption.
67
Q

Arrange the nolla stages:
A. Crown almost completed
B. 2/3 root completed (the tooth breaks the alveolar process and appears in the mouth)
C. Crypt present
D. Root almost completed
E. 1/3 crown completed
F. Crypt absent
G. 1/3 root completed
H. 2/3 crown completed
I. Initial calcification
J. Crown completed (eruptive period begins)
K. Root apex completed

A

A. 5
B. 8
C. 1
D. 9
E. 3
F. 0
G. 7
H. 4
I. 2
J. 6
K. 10

68
Q

When does root formation begin?

A

After enamel and dentin are well developed

69
Q

The inner and outer enamel epithelium come together in the ? region and form an epithelial
fold, the epithelial root sheath or Hertwig epithelial root sheath (HERS), which grows into the mesenchyme and begins the formation of the root.

A

Neck region

70
Q

What happens to the pulp cavity as the dentin increases?

A

Gets smaller and becomes a narrow canal for the vessels and nerves to enter to the root

71
Q

Union between IEE and OEE is?

A

Hertwigs epithelial root sheath

72
Q

What produces cementoblasts?

A

The inner cells of the dental sac

73
Q

Where do the cementum and enamel meet?

A

The neck of the tooth
CEJ

74
Q

Hertwig epithelial root sheath (HERS) disintegrates and its remnants are called?

A

epithelial rests of Malassez