Chapter 5: Development and Plasticity and Chapter 6: Vision Flashcards
Neural tube
fluid-filled cavity results in CNS development
differentiation
process makes one neuron different from another; beings as neuron is migrating, is also dependent on local environment of target destination. Axon develop first and cell shape and dendrites develop once neuron reaches target site
Proliferation
cells lining ventricles divide
Migration
proliferating cells migrate toward destinations in CNS.
Migration is guided by what?
immunoglobins, chemokines, radial glia
Myelination
production of myelin sheaths around axons. first occurs in spinal cord, then hindbrain, midbrain, forebrain. occurs gradually for decades
Synaptogenesis
formation of new synapses. occurs throughout life
Neurotrophins
chemicals that promote neuron survival and growth
Types of Neurotrophins
nerve growth factor, brain derived neurotropic, neurotrophins 3, 4/5, and 6
Apoptosis
programmed cell death
behavioral compensation
subject learns to use remaining portions of NS to compensate for damage
Phantom limb
continuation of sensation of an amputated body part
Denervation and Disuse supersensitivity
heightened sensitivity to a neurotransmitter after the destruction of an incoming axon or inactivity
potential mechanisms
up-regulation of receptor proteins; up-regulation of a following cascade component (ion channels, secondary messengers)
Ischemia
Most common type of stroke; resulting from blood clot or obstruction of an artery. Neurons lose oxygen and glucose supply
Hemorrhage
less frequent type of stroke; results from ruptured artery. Neurons flooded with excess calcium, oxygen, and other products
Edema
the accumulation of fluid in brain resulting in increased pressure on the brain & increasing probability of strokes
Ischema & Hemorrhage may cause:
Edema & disruption of sodium-potassium pump leading to accumulation of sodium ions inside neurons
Tissue plasminogen activator (tPA)
breaks up blood clots and reduces the effects of an ischemic stroke
penumbra
region that surrounds the immediate damage
Cannabinoids (pot)
potentially minimize cell loss through antioxidant and anti-inflammatory actions
One of most effective lab methods to minimize stroke damage
cooling the brain
Sensory Receptors
organs that are in your body, mostly on surface, that allow external world to communicate with your brain
Types of Sensory Receptors
Chemoreceptors; Mechanoreceptors; Thermal Receptors; Pain Receptors; Light Receptors
Adequate Stimulus
sensory receptors are “tuned” to respond best to a certain type of stimulus energy.
Generator Potential
a graded potential produced in some types of receptor cells
Sensory Adaptation
receptors reduce their sensitivity if continuously stimulated
Reception
first physical interaction between the stimulus energy and sensory receptor
Transduction
conversion of physical energy of stimulus into an electrochemical response
Coding
correspondence between some aspect of the physical stimulus and aspect of neural activity
intensity
strength of the stimulus. represented by rate of action potentials
quality
type of stimulus. can include variety of stimulus features over and beyond intensity