Chapter 5: Development and Plasticity and Chapter 6: Vision Flashcards
Neural tube
fluid-filled cavity results in CNS development
differentiation
process makes one neuron different from another; beings as neuron is migrating, is also dependent on local environment of target destination. Axon develop first and cell shape and dendrites develop once neuron reaches target site
Proliferation
cells lining ventricles divide
Migration
proliferating cells migrate toward destinations in CNS.
Migration is guided by what?
immunoglobins, chemokines, radial glia
Myelination
production of myelin sheaths around axons. first occurs in spinal cord, then hindbrain, midbrain, forebrain. occurs gradually for decades
Synaptogenesis
formation of new synapses. occurs throughout life
Neurotrophins
chemicals that promote neuron survival and growth
Types of Neurotrophins
nerve growth factor, brain derived neurotropic, neurotrophins 3, 4/5, and 6
Apoptosis
programmed cell death
behavioral compensation
subject learns to use remaining portions of NS to compensate for damage
Phantom limb
continuation of sensation of an amputated body part
Denervation and Disuse supersensitivity
heightened sensitivity to a neurotransmitter after the destruction of an incoming axon or inactivity
potential mechanisms
up-regulation of receptor proteins; up-regulation of a following cascade component (ion channels, secondary messengers)
Ischemia
Most common type of stroke; resulting from blood clot or obstruction of an artery. Neurons lose oxygen and glucose supply