Chapter 5 Flashcards
Hypodermis
The skin rests on this, it is like the foundation to a house, the hypodermis attaches to underlying bone and muscle and supplies to nerves and blood vessels
Consisted of loose connective tissue with collagen and elastin fibers
Contains mainly: fibroblasts, macrophages, and adipocytes
๐ฅ hypodermis is not part of the skin, is sometimes called subcutaneous tissue or superficial fascia.
Half the bodyโs far is in the hypodermis
Dermis
The tissue layer connected to the hypodermis
Responsible for structural strength of the skin
Composed of: fibroblasts, adipose cells, connective tissue, macrophages
Divided into two layers
Epidermis
Is a layer of epithelial tissue that rests on the dermis
5 major functions of the integumentary system
- Protection- against abrasion, ultraviolet light, and prevents entry of microorganisms, prevents dehydration by reducing water loss
- Sensation- can detect heat, cold, touch, pain, pressure
- Temperature regulation- by controlling blood flow and sweat glands
- Vitamin D production- exposure to ultraviolet light makes vitamin D
- Excretion- waste is released through sweat glands
Two layers of the dermis
Reticular layer- deeper layer
Papillary layer- more superficial
Cleavage or tension lines
The elastin or collagen fibers are oriented more in some directions than others
Striae or stretch marks
If the skin is over stretched, the dermis may rupture and leave lines that are visible through the epidermis
Papillae
The papillary layer derives itโs name from projections called papillae that extend toward the epidermis
Keratinocytes
Responsible for structural strength and permeability characteristics of the epidermis.
Most cells in the epidermis are called this because they produce keratin
Melanocytes
Contain melanin and contribute to skin color
Langerhans cells
Are part of the immune system
Merkelโs cells
Specialized epidermal cells associated with nerve endings responsible for detecting light tough and superficial pressure.
Desquamate
As new cells are formed, they push older cells to the surface where they slough off, or desquamate
Keratinization
As cells move towards the surface of the skin to eventually fall off they change shape and chemical composition
Strata
On the basis of these stages the many layers of cells in the epidermis are divided into regions, or strata.
Five strata of the epidermis
Stratum corneum Stratum lucidium Stratum granulosum Stratum spinosum Stratum basale
Stratum basale
Cells divide by mitosis and some newly formed cells become the cells of the more superficial strata
Stratum spinosum
Keratin fibers and lamellar bodies accumulate
Stratum granulosum
Keratohyalin granules accumulate and a hard protein envelope forms beneath the plasma membrane, lamellar bodies release lipids; cells die.
Stratum lucidum
The cells are dead and contain dispersed keratohyalin
Stratum corneum
The dead cells have a hard protein envelope, contain keratin, and are surrounded by lipids.
Lamellar bodies
Additional keratin fibers and lipid-filled, membrane bounded organelles called lamellar bodies are formed inside the keratinocytes
Cornfield cells
Dead cells with hard protein envelope that are filled with protein keratin
Thick skin
Has all five epithelial strata, and the stratum corneum has many layers, thick skin is found areas subject to pressure or friction such as the palms of the hands, the soles of the feet, and fingertips.
Thin skin
Covers the rest of the body and is more flexible than thick skin is
Callus
In skin subjected to friction or pressure, the number of layers in the stratum corneum greatly increases to produce a thickened area called a callus
Corn
The akin over bony prominences may develop a cone-shaped structure called corn.
Melanin
Is the term used to describe a group of pigments responsible for skin, hair, and eye color.
Melanin also provides protection against ultraviolet light from the sun
Melanocytes
Melanin is produced by this,
They are irregularly shaped cells with many long processes that extend between the keratinocytes of the stratum basale and the stratum spinosum
Albinism
Usually is a recessive genetic trait causing an inability to produce tyrosinase
Melanosomes
The Golgi apparatuses of the melanocytes package melanin into vesicles called melanosomes which move into the cell processes of the melanocytes
Cyanosis
A decrease in blood flow such as occurs in shock can make the skin appear pale, and a decrease in the blood oxygen content produces cyanosis, a blueish skin color ๐ฆ๐ฆ๐ง๐ฌ๐ณ๐๐โ๏ธ๐๐จ๐๐๐๐๐๐ซ๐ช๐ฌ๐ญ๐ป๐๐พ๐ป๐๐๐บ๐พ๐ฐ๐ ฟ๏ธโฟ๏ธ๐ญ๐โ๏ธ๐๐๐ ๐๐ง๐ โฟ๐ต๐ท๐น
Carotene
A yellow pigment found in plants such as carrots and corn, humans inject as a source of vitamin A. Carotene is lipid soluble so when large amounts are ingested excess can accumulate in the stratum corneum turning the skin yellow ๐๐ซ๐๐๐ฎ๐ฌ๐ถ๐ฏ๐๐ง๐ฆ๐๐๐๐โ๏ธโญ๏ธโก๏ธ๐๐ฝ๐๐โ๏ธ๐๐โ ๏ธ๐๐ค๐๐ซ๐๐๐๐๐๐๐๐ฑ๐ค๐ฅ