Chapter 5 Flashcards
What tissue is epidermis made of
Keratinized stratified squamous
Cells in epidermis
Keratinocytes
Melanocytes
Intraepidermal macrophages
Tactile epithelial cells
Keratinocytes
Produce keratin/lamellar granules (releases water repellent sealant desires water entry/loss foreign particle entry)
Melanocytes
Produce melanin
Form veil over keratinocytes nucleus to protect from UV
Intraepidermal Macrophages/langerhen cells
Help immune system recognize/destroy invading microbes
Tactile epithelial cells (Merkel cells)
Contact tactile/merkel discs detect touch sensations
Thin skin layer
Basum, spinosum, granulosum, thin corneum
Thick skin layers
Basum, spinsosum, granulosom, lucidum, thick corneum
Stratum basale
Deepest layer, single row cuboidal/columnar keratinocytes, stem cells, tactile discs/cells
Stratum spinosum
8-10 layers of keratinocytes Desosomes keratin intermediate filaments, Intraepidermal macrophages, melanocytes
Stratum granulosum
Keratinocytes undergo apoptosis
Keratohylin
Lamellar granules
Stratum lucidum
Thick skin 4-6 layers dead keratinocytes
Stratum corneum
Few to 50 (25-30) layers desd keratinocytes
No nuclei/organelles
What tissue is dermis made of
Dense irregular connective tissue
Regions of dermis
Papillary
Reticular
Papillary
1/5
Collagen/fine elastic fibers
Dermal papillae increase SA
Free nerve vending
Dendrites lacking structural specialization
Reticular region
4/5 thickness
Thick collagen/elastic fibers scattered fibroblast wandering called
Collagen Fibers arranges netlike=resist stretching
BV, nerves, hair follicles sebaceous sudoriferous
Basis for skin colour
Melanin
Hemoglobin
Carotene
Hair shaft
Superficial portion
Hair root
Deep portion penetrates dermis sometimes subcutaneous
Medulla cortex cuticle
Medulla
Inner portion
Pigment cells
Cortex
Middle portion
Elongated cells
Cuticle of hair
Outermost later
Heavily Keratinized
Hair follicle
Surrounds root
Epithelial root sheath
Epithelial root sheath
External
Internal
External roots sheath
Downward continuation of dermis
Internal root sheath
Procured by matrix
Dermal root sheath
Dense dermis surrounding hair follicle
Hair bulb
Base of hair follicle and dermal root sheath
Papilla
Nipple shaped BV Areolar connective tissue
Hair matrix
Germinal layer of cells responsible for hair growth
Arrector pili
Muscle on hair goosebumps
Sebaceous glands
Lips penis labia less on trunks/limbs
Excrete onto dermis
Mostly connected to hair follicle
Secretes sebum
Prevent hair dryness water loss skin rough inhibit growth of bacteria
Activated in puberty
Sudiferous glands types
Eccrine
Apocrine
Eccrine
Mostly forehead palms soles
Deep dermis
Surface of epidermis
Perspiration
Body temp/waste removal emotional stress
Soon after birth
Apocrine
Axillae groin Areolae labia bearer regions
Deep dermis/subcutaneous
Hair follicles
Perspiration
Emotional/sexual stress
Puberty
Ceremonious
External auditory canal
Subcutaneous
Surface of canal/sebaceous ducts
Cerumen
Stop entrance of foreign particles/waterproof
Soon after birth
Nail body
Visible portion
Free edge
Extend past distal end of digit
Nail root
Under layer of skin
Lunula
White crescent shape can’t see vascular tissue
Hypnychium
Join free edge and fingertip
Nail bed
Below nail
Eponychium
Cuticle consists of stratum corneum
Nail matrix
Epithelium proximal to nail root
Thin vs thick skin
Thin: not on palms/soles
.1-.15mm
No lucidum
No epidermal ridges
Has hair follicles
Has sebaceous glands
Less sudiferous
Less sensory receptors
Thick
Only palms/soles
.6-4.5mm
Has lucidum
Has epidermal ridges
No hair follicles
No sebaceous
More sudiferous
More touch receptors
Thermoregulation with skin
Sweat=lower body temp
Dilate BV=lower body temp
Blood reservoir of skin
Intense network holding 8-10% of blood
Protection with skin
Keratin
Lamented granules
Sebaceous
Sudoriferous
Melanin
Intraepidermal macrophages
Sensation with ski
Cutaneous sensation: tactile/thermal/pain
Tactile discs corpuscles of touch hair root plexus’s
How much water skin secretes
400ml daily
Skin abosorb
Water certain lipid soluble vitamins, drugs, gases
Vitamin D synthesis with skin
Activation of precursor molecule by UV (10-15 mins 2/week)
Enzymes in liver/kidney modify activated molecule
Produce calcitriol
Epidermis, dermis, subcutaneous tissues
Epithelial
Connective
Areolar/adipose
Cutaneous membrane
Skin
Extensibility
Ability to stretch
Elasticity
Ability to return to normal after stretching
Epidermal ridges
Downward projection of epidermis into dermis between dermal papillae
Strong bond
Increase SA=sensitive
Increase friction=grip
Thermoregulatory sweating
First in forhead/scalp
Insensible: evaporates before seen
Sensible: evaporates after seen
Emotional sweating
First palms/soles