Chapter 48 Muscle

Question 1

Genetic cause of myotonic dystrophy*
A. Mutation in DMPK
B. Mutation in ZNF9
C. Mutation in ZASP
D. Mutation in T1A1

Answer 1

A. Mutation in DMPK (p. 1436)

Question 2

May be associated with congenital absence of muscle such as pectoralis and biceps*
A. Duchenne
B. Becker
C. Emery-Dreyfuss
D. Limb girdle muscular dystrophy
E. Fascioscapulohumeral dystrophy

Answer 2

E. Fascioscapulohumeral dystrophy (p. 1458)

Question 3

Isolated weakness of the quadriceps is most likely due to*
A. Steroids
B. Diabetes
C. Hypothyroidism
D. Chemotherapeutic agents

Answer 3

A. Steroids (p. 1415)

Question 4

In older adults, the most common cause of isolated quadriceps femoris weakness is*
A. Inclusion body myositis
B. Dermatomyositis
C. Polymyositis
D. Duchenne muscular dystrophy

Answer 4

A. Inclusion body myositis (p. 1415)

Question 5

56-year-old male presents with weakness, beginning with the finger flexors. He also had proximal weakness of the legs. What is the most likely diagnosis?*
A. Polymyositis
B. Dermatomyositis
C. Inclusion body myositis
D. DMD

Answer 5

C. Inclusion body myositis (p. 1423)