Chapter 45 - Electrophysiologic & Laboratory Aids in Neuromuscular Disease Flashcards

1
Q
Main intracellular constituents in nerve and muscle EXCEPT
A. Potassium
B. Magnesium
C. Phosphorus
D. Calcium
A

D. Calcium (p. 1288)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q
The following synaptic disorders impede presynaptic release of Ach EXCEPT
A. Myasthenia gravis
B. Botulism
C. Aminoglycoside antibiotic toxicity
D. LEMS
A

A. Myasthenia gravis (p. 1290)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q
Non-depolarizing neuromuscular blocker/s
A. Curare/curariform drugs
B. Succinylcholine
C. Decamethonium
D. B and C only
E. All of the above
A

A. Curare/curariform drugs (p. 1290)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q
Depolarizing neuromuscular blocker/s
A. Curare/curariform drugs
B. Succinylcholine
C. Decamethonium
D. B and C only
E. All of the above
A

D. B and C only (p. 1290)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q
Irreversible blocker/s of cholinesterase function
A. Neostigmine
B. Physostigmine
C. Pyridostigmine
D. Organophosphates
E. A, B, and C only
F. All of the above
A

D. Organophosphates (p. 1290)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which of the following is NOT true regarding atropine?
A. Used in the treatment of organophosphate toxicity
B. Active at muscarinic sites
C. Exerts its effect at the NMJ
D. None of the above

A

C. Exerts its effect at the NMJ (p. 1290)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q
The most readily available source of muscular energy
A. Glycogen
B. Blood glucose
C. Free fatty acids
D. Muscle protein
A

A. Glycogen (p. 1292)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q
Rich in oxidative enzymes
A. Type 1 fibers
B. Type 2 fibers
C. Both
D. Neither
A

A. Type 1 fibers (p. 1292)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
Contain more mitochondria
A. Type 1 fibers
B. Type 2 fibers
C. Both
D. Neither
A

A. Type 1 fibers (p. 1292)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q
Larger amounts of myoglobin, therefore appearing red
A. Type 1 fibers
B. Type 2 fibers
C. Both
D. Neither
A

A. Type 1 fibers (p. 1292)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q
Slower rates of contraction and relaxation, fire more tonically, and are less fatigable
A. Type 1 fibers
B. Type 2 fibers
C. Both
D. Neither
A

A. Type 1 fibers (p. 1292)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q
Fire in bursts and are used in quick phasic reactions
A. Type 1 fibers
B. Type 2 fibers
C. Both
D. Neither
A

B. Type 2 fibers (p. 1292)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q
Stain lightly with myosin ATPase stain at pH 9.4
A. Type 1 fibers
B. Type 2 fibers
C. Both
D. Neither
A

A. Type 1 fibers (p. 1292)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q
Stain darkly with myosin ATPase stain at pH 9.4
A. Type 1 fibers
B. Type 2 fibers
C. Both
D. Neither
A

B. Type 2 fibers (p. 1292)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
The most consistent and most sensitive measure of skeletal muscle damage
A. Transaminase
B. Lactic acid dehydrogenase
C. Aldolase
D. Serum CK
A

D. Serum CK (p. 1293)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q
Which of the following is NOT a hallmark of demyelinating lesions?
A. Decrease in amplitude of CMAPs
B. Prolonged distal latencies
C. Slowed conduction velocities
D. Conduction blocks
E. Dispersed responses
A

A. Decrease in amplitude of CMAPs (p. 1296)

17
Q

Which among the following will NOT show an increase in insertional activity during needle EMG?
A. Denervation
B. Primary muscle disease
C. Disorders that dispose to muscle cramps
D. Advanced myopathy

A

D. Advanced myopathy (p. 1301)

18
Q
Which among the following are not generated by muscle fibers?
A. Fibrillations
B. Positive sharp waves
C. Complex repetitive discharges
D. Fasciculation potentials
A

D. Fasciculation potentials (p. 1303)

19
Q
Which of the following is NOT generated by the motor unit?*
A. Fibrillations
B. Fasciculations
C. Myokimic discharges
D. Neuromyotonia
E. Cramp syndromes
A

A. Fibrillations (p. 1303)

20
Q
"Dive-bomber" sound on EMG is typical of
A. Complex repetitive discharges
B. Myokymia
C. Myotonia
D. Cramp syndromes
A

C. Myotonia (p. 1303)

21
Q

The following are characteristic of MUPs in myopathy EXCEPT
A. Giant polyphasic potentials
B. Low-voltage short-duration polyphasic potentials
C. Early recruitment
D. “Rain-falling-on-a-tin-roof” sound heard from the EMG audio monitor

A

A. Giant polyphasic potentials (p. 1305)

22
Q

Most specific histologic evidence of denervation and reinnervation
A. Reduction in the size of muscle fibers
B. Enlargement of intact motor units
C. Group atrophy
D. Fiber type grouping

A

D. Fiber type grouping (p. 1306)