Chapter 45 - Electrophysiologic & Laboratory Aids in Neuromuscular Disease Flashcards
Main intracellular constituents in nerve and muscle EXCEPT A. Potassium B. Magnesium C. Phosphorus D. Calcium
D. Calcium (p. 1288)
The following synaptic disorders impede presynaptic release of Ach EXCEPT A. Myasthenia gravis B. Botulism C. Aminoglycoside antibiotic toxicity D. LEMS
A. Myasthenia gravis (p. 1290)
Non-depolarizing neuromuscular blocker/s A. Curare/curariform drugs B. Succinylcholine C. Decamethonium D. B and C only E. All of the above
A. Curare/curariform drugs (p. 1290)
Depolarizing neuromuscular blocker/s A. Curare/curariform drugs B. Succinylcholine C. Decamethonium D. B and C only E. All of the above
D. B and C only (p. 1290)
Irreversible blocker/s of cholinesterase function A. Neostigmine B. Physostigmine C. Pyridostigmine D. Organophosphates E. A, B, and C only F. All of the above
D. Organophosphates (p. 1290)
Which of the following is NOT true regarding atropine?
A. Used in the treatment of organophosphate toxicity
B. Active at muscarinic sites
C. Exerts its effect at the NMJ
D. None of the above
C. Exerts its effect at the NMJ (p. 1290)
The most readily available source of muscular energy A. Glycogen B. Blood glucose C. Free fatty acids D. Muscle protein
A. Glycogen (p. 1292)
Rich in oxidative enzymes A. Type 1 fibers B. Type 2 fibers C. Both D. Neither
A. Type 1 fibers (p. 1292)
Contain more mitochondria A. Type 1 fibers B. Type 2 fibers C. Both D. Neither
A. Type 1 fibers (p. 1292)
Larger amounts of myoglobin, therefore appearing red A. Type 1 fibers B. Type 2 fibers C. Both D. Neither
A. Type 1 fibers (p. 1292)
Slower rates of contraction and relaxation, fire more tonically, and are less fatigable A. Type 1 fibers B. Type 2 fibers C. Both D. Neither
A. Type 1 fibers (p. 1292)
Fire in bursts and are used in quick phasic reactions A. Type 1 fibers B. Type 2 fibers C. Both D. Neither
B. Type 2 fibers (p. 1292)
Stain lightly with myosin ATPase stain at pH 9.4 A. Type 1 fibers B. Type 2 fibers C. Both D. Neither
A. Type 1 fibers (p. 1292)
Stain darkly with myosin ATPase stain at pH 9.4 A. Type 1 fibers B. Type 2 fibers C. Both D. Neither
B. Type 2 fibers (p. 1292)
The most consistent and most sensitive measure of skeletal muscle damage A. Transaminase B. Lactic acid dehydrogenase C. Aldolase D. Serum CK
D. Serum CK (p. 1293)
Which of the following is NOT a hallmark of demyelinating lesions? A. Decrease in amplitude of CMAPs B. Prolonged distal latencies C. Slowed conduction velocities D. Conduction blocks E. Dispersed responses
A. Decrease in amplitude of CMAPs (p. 1296)
Which among the following will NOT show an increase in insertional activity during needle EMG?
A. Denervation
B. Primary muscle disease
C. Disorders that dispose to muscle cramps
D. Advanced myopathy
D. Advanced myopathy (p. 1301)
Which among the following are not generated by muscle fibers? A. Fibrillations B. Positive sharp waves C. Complex repetitive discharges D. Fasciculation potentials
D. Fasciculation potentials (p. 1303)
Which of the following is NOT generated by the motor unit?* A. Fibrillations B. Fasciculations C. Myokimic discharges D. Neuromyotonia E. Cramp syndromes
A. Fibrillations (p. 1303)
"Dive-bomber" sound on EMG is typical of A. Complex repetitive discharges B. Myokymia C. Myotonia D. Cramp syndromes
C. Myotonia (p. 1303)
The following are characteristic of MUPs in myopathy EXCEPT
A. Giant polyphasic potentials
B. Low-voltage short-duration polyphasic potentials
C. Early recruitment
D. “Rain-falling-on-a-tin-roof” sound heard from the EMG audio monitor
A. Giant polyphasic potentials (p. 1305)
Most specific histologic evidence of denervation and reinnervation
A. Reduction in the size of muscle fibers
B. Enlargement of intact motor units
C. Group atrophy
D. Fiber type grouping
D. Fiber type grouping (p. 1306)
