Chapter 33 - Viral infections Flashcards
Most frequent symptom of acute aseptic meningitis
A. Drowsiness
B. Headache that is more severe than that associated with other febrile states
C. Photophobia
D. Neck and spine stiffness
B. Headache that is more severe than that associated with other febrile states (p. 744)
Most common cause of acute aseptic meningitis A. Enterovirus B. HSV C. Varicella D. CMV
A. Enterovirus (p. 744)
Most common identifiable cause of chronic and recurrent aseptic meningitis A. Tuberculosis B. Fungal C. Vasculitis D. Syphilis
A. Tuberculosis (p. 747)
Causative agent associated with Mollaret recurrent meningitis A. Tuberculosis B. HSV 1 C. Enterovirus D. Syphilis
B. HSV 1 (p. 747)
Most common sporadic cause of encephalitis A. HSV B. Japanese encephalitis virus C. West Nile virus D. Rabies
A. HSV (p. 749)
Which of the following is not transmitted via retrograde axonal transport?* A. Rabies B. Varicella C. Polio D. HSV
C. Polio (p. 743)
Which shows periodic lateralized epileptiform discharges?* A. HSV encephalitis B. Deeply anesthetized patient C. GBM D. CJD
A. HSV encephalitis (p. 751)
Negri bodies A. Arbovirus B. HSV C. HHV 6 D. Rabies
D. Rabies (p. 754)
Babes nodules A. Arbovirus B. HSV C. HHV 6 D. Rabies
D. Rabies (p. 754)
Multinucleated giant cells in scrapings from the base of an early vesicle (Tzanck smear) A. Rabies B. VZV C. CMV D. EBV
B. VZV (p. 756)
Most common site of herpes zoster* A. T1-T5 B. T3-T8 C. T5-T10 D. L1-5
C. T5-10 (p. 756)
Ramsay-Hunt syndrome A. HSV B. VZV C. CMV D. EBV
B. VZV (p. 756)
Most common neurologic complication in the later stages of HIV infection A. AIDS dementia complex B. Vacuolar myelopathy C. Distal sensory polyneuropathy D. Myopathy
A. AIDS dementia complex (p. 759)
Most frequent focal cerebral infectious complication among AIDS patients A. Toxoplasmosis B. CMV infection C. Cryptococcosis D. Syphilis
A. Toxoplasmosis (p. 761)
Most frequent fungal complication of HIV infection A. Candidemia B. Cryptococcosis C. Aspergillosis D. Histoplasmosis
B. Cryptococcosis (p. 761)
The main reservoir of poliomyelitis agent A. Intestinal tract B. Lumbar sensory ganglia C. Cranial sensory ganglia D. Thoracic sensory ganglia
A. Intestinal tract (p. 763)
The only known natural host of poliomyelitis agent A. Wild birds B. Monkeys C. Fowl D. Humans
D. Humans (p. 763)
Main route of infection of poliomyelitis A. Respiratory B. Fecal-oral C. Direct inoculation D. Transplacental
B. Fecal-oral (p. 763)
Most frequently involved cranial muscles in poliomyelitis A. Muscles of facial expression B. EOMs C. Muscles of deglutition D. Muscles of phonation
C. Muscles of deglutition (p. 764)
Earliest histopatholigic change in the anterior horns of the spinal cord in poliomyelitis A. Neuronophagia B. Central chromatolysis + inflammation C. Axonal swelling D. All of the above
B. Central chromatolysis + inflammation (p. 764)
EEG findings consisting of periodic (every 5-9 s) bursts of 2-3/s high-voltage waves followed by a relatively flat pattern A. SSPE B. HSV encephalitis C. CJD D. PML
A. SSPE (p. 766)
Histopathologic hallmark of SSPE A. Destruction of nerve cells B. Neuronophagia C. Perivenous cuffing D. Eosinophilic inclusions
D. Eosinophilic inclusions (p. 766)
Pathogenesis of CJD*
A. PrPc to PrPsc
B. PrPsc to PrPc
C. Increase in protein’s helical proportion
D. Decrease in protein’s beta pleated sheet proportion
A. PrPc to PrPsc (p. 770)
Most common type of CJD A. MM1 B. MM2 C. MV1 D. MV2
A. MM1 (p. 770)
Type of CJD that is most likely to have a typical EEG pattern A. M type B. V type C. Type 1 D. Type 2
C. Type 1 (p. 770)
Type of CJD that is most likely to show typical MRI changes A. MM1 B. MM2 C. MV1 D. MV2
D. MV2 (p. 770)
EEG in CJD A. Triphasic waves B. Periodic sharp wave complexes C. 3-Hz spike-and-wave complexes D. Occipital spikes
B. Periodic sharp wave complexes (p. 771)
Which is NOT true of HTLV-I infection?*
A. HTLV-I myelopathy is also known as tropical spastic parapresis
B. Only a small portion of HTLV-I-infected persons develop a myelopathy
C. No form of treatment has proved effective in reversing the disorder
D. HTLV-II is less common than HTLV-I
E. None of the above
E. None of the above (p. 762)