Chapter 33 - Viral infections Flashcards

1
Q

Most frequent symptom of acute aseptic meningitis
A. Drowsiness
B. Headache that is more severe than that associated with other febrile states
C. Photophobia
D. Neck and spine stiffness

A

B. Headache that is more severe than that associated with other febrile states (p. 744)

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2
Q
Most common cause of acute aseptic meningitis
A. Enterovirus
B. HSV
C. Varicella
D. CMV
A

A. Enterovirus (p. 744)

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3
Q
Most common identifiable cause of chronic and recurrent aseptic meningitis
A. Tuberculosis
B. Fungal
C. Vasculitis
D. Syphilis
A

A. Tuberculosis (p. 747)

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4
Q
Causative agent associated with Mollaret recurrent meningitis
A. Tuberculosis
B. HSV 1
C. Enterovirus
D. Syphilis
A

B. HSV 1 (p. 747)

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5
Q
Most common sporadic cause of encephalitis
A. HSV
B. Japanese encephalitis virus
C. West Nile virus
D. Rabies
A

A. HSV (p. 749)

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6
Q
Which of the following is not transmitted via retrograde axonal transport?*
A. Rabies
B. Varicella
C. Polio
D. HSV
A

C. Polio (p. 743)

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7
Q
Which shows periodic lateralized epileptiform discharges?*
A. HSV encephalitis
B. Deeply anesthetized patient
C. GBM
D. CJD
A

A. HSV encephalitis (p. 751)

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8
Q
Negri bodies
A. Arbovirus
B. HSV
C. HHV 6
D. Rabies
A

D. Rabies (p. 754)

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9
Q
Babes nodules
A. Arbovirus
B. HSV
C. HHV 6
D. Rabies
A

D. Rabies (p. 754)

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10
Q
Multinucleated giant cells in scrapings from the base of an early vesicle (Tzanck smear)
A. Rabies
B. VZV
C. CMV
D. EBV
A

B. VZV (p. 756)

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11
Q
Most common site of herpes zoster*
A. T1-T5
B. T3-T8
C. T5-T10
D. L1-5
A

C. T5-10 (p. 756)

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12
Q
Ramsay-Hunt syndrome
A. HSV
B. VZV
C. CMV
D. EBV
A

B. VZV (p. 756)

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13
Q
Most common neurologic complication in the later stages of HIV infection
A. AIDS dementia complex
B. Vacuolar myelopathy
C. Distal sensory polyneuropathy
D. Myopathy
A

A. AIDS dementia complex (p. 759)

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14
Q
Most frequent focal cerebral infectious complication among AIDS patients
A. Toxoplasmosis
B. CMV infection
C. Cryptococcosis
D. Syphilis
A

A. Toxoplasmosis (p. 761)

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15
Q
Most frequent fungal complication of HIV infection
A. Candidemia
B. Cryptococcosis
C. Aspergillosis
D. Histoplasmosis
A

B. Cryptococcosis (p. 761)

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16
Q
The main reservoir of poliomyelitis agent
A. Intestinal tract
B. Lumbar sensory ganglia
C. Cranial sensory ganglia
D. Thoracic sensory ganglia
A

A. Intestinal tract (p. 763)

17
Q
The only known natural host of poliomyelitis agent
A. Wild birds
B. Monkeys
C. Fowl
D. Humans
A

D. Humans (p. 763)

18
Q
Main route of infection of poliomyelitis
A. Respiratory
B. Fecal-oral
C. Direct inoculation
D. Transplacental
A

B. Fecal-oral (p. 763)

19
Q
Most frequently involved cranial muscles in poliomyelitis
A. Muscles of facial expression
B. EOMs
C. Muscles of deglutition
D. Muscles of phonation
A

C. Muscles of deglutition (p. 764)

20
Q
Earliest histopatholigic change in the anterior horns of the spinal cord in poliomyelitis
A. Neuronophagia
B. Central chromatolysis + inflammation
C. Axonal swelling
D. All of the above
A

B. Central chromatolysis + inflammation (p. 764)

21
Q
EEG findings consisting of periodic (every 5-9 s) bursts of 2-3/s high-voltage waves followed by a relatively flat pattern
A. SSPE
B. HSV encephalitis
C. CJD
D. PML
A

A. SSPE (p. 766)

22
Q
Histopathologic hallmark of SSPE
A. Destruction of nerve cells
B. Neuronophagia
C. Perivenous cuffing
D. Eosinophilic inclusions
A

D. Eosinophilic inclusions (p. 766)

23
Q

Pathogenesis of CJD*
A. PrPc to PrPsc
B. PrPsc to PrPc
C. Increase in protein’s helical proportion
D. Decrease in protein’s beta pleated sheet proportion

A

A. PrPc to PrPsc (p. 770)

24
Q
Most common type of CJD
A. MM1
B. MM2
C. MV1
D. MV2
A

A. MM1 (p. 770)

25
Q
Type of CJD that is most likely to have a typical EEG pattern
A. M type
B. V type
C. Type 1
D. Type 2
A

C. Type 1 (p. 770)

26
Q
Type of CJD that is most likely to show typical MRI changes
A. MM1
B. MM2
C. MV1
D. MV2
A

D. MV2 (p. 770)

27
Q
EEG in CJD
A. Triphasic waves
B. Periodic sharp wave complexes
C. 3-Hz spike-and-wave complexes
D. Occipital spikes
A

B. Periodic sharp wave complexes (p. 771)

28
Q

Which is NOT true of HTLV-I infection?*
A. HTLV-I myelopathy is also known as tropical spastic parapresis
B. Only a small portion of HTLV-I-infected persons develop a myelopathy
C. No form of treatment has proved effective in reversing the disorder
D. HTLV-II is less common than HTLV-I
E. None of the above

A

E. None of the above (p. 762)