Chapter 44 Flashcards
levothyroxine for thyroid hormone replacement
Synthetic T4
Highly individualized doses
Increase dose at 4-6 weeks if have CVD
Serum TSH levels regularly monitored
Admin medication at same time every day
-High TSH=need higher dose
AE:
- hyperthyroidism
- Black box*: Use of thyroid hormone in treatment of obesity or weight loss is contraindicated.
methimazole (Tapazole) for hyperthyroidism
Interferes w/ synthesis of T3 and T4
Effects:
-Normal thyroid function: weight gain, lower anxiety, less insomnia, lower HR
-*Notify provider immediately if pregnancy expected
AE:
-Hepatotoxic
Don’t use with warfarin
Hydrocortisone pharmacotherapy
Corticosteroid
mimics cortisol- can treat:
- Inflammation
- allergic reactions
- Can be injected into inflamed joints
- Use correct route
- Admin same time every day
AE:
-Cushing’s symptomsFluid retention
CNS effects
Don’t use if have an infection
Desmopressin (DDVAP) pharmacotherapy
Synthetic ADH->increase reabsorption of water
Used to control acute DI
Prod. clotting factor VIII->bleeding management for hemophilia A and von willebrand’s.
Can be used for fixing betwetting/nighttime polyuria (less urine production)
-After IV restrict fluid to prevent water intoxication
AE:
- Water intoxication
- Black box: Can cause hyponatremia
Don’t use if DI caused by kidney disease.