Chapter 40: Infective Endocarditis Flashcards
A nurse is caring for a patient with suspected infective endocarditis (IE). Which assessment finding is most concerning and requires immediate follow-up?
a. A new onset of a loud systolic murmur
b. Splinter hemorrhages in the nail beds
c. Fatigue and low-grade fever
d. Janeway lesions on the palms and soles
a. A new onset of a loud systolic murmur
Rationale: A new or worsening murmur may indicate valve damage or dysfunction, which is a critical complication of IE and requires immediate evaluation. Splinter hemorrhages, fatigue, fever, and Janeway lesions are common findings in IE but are not as urgent.
A 35-year-old patient with a history of IV drug use is diagnosed with infective endocarditis. What is the priority nursing intervention?
a. Teach the patient about the importance of a low-sodium diet
b. Prepare the patient for valve replacement surgery
c. Administer prophylactic antibiotics before invasive procedures
d. Monitor for signs of embolic complications
d. Monitor for signs of embolic complications
Rationale: Embolic complications, such as stroke, pulmonary embolism, or organ infarction, are common in IE and can be life-threatening. Monitoring for these complications is the priority. Other interventions may be relevant but are not the immediate priority.
Which patient is at the highest risk for developing infective endocarditis (IE)?
a. A 45-year-old with uncontrolled hypertension
b. A 30-year-old IV drug user with a history of hepatitis C
c. A 60-year-old with a history of atrial fibrillation on anticoagulants
d. A 50-year-old with peripheral artery disease
b. A 30-year-old IV drug user with a history of hepatitis C
Rationale: IV drug use introduces bacteria directly into the bloodstream, significantly increasing the risk of IE. The other conditions do not have the same direct association with IE.
A nurse is educating a patient with infective endocarditis about antibiotic therapy. Which statement by the patient indicates a need for further teaching?
a. “I will need to take antibiotics for several weeks to clear the infection.”
b. “I should report any symptoms of fever or fatigue to my healthcare provider.”
c. “Once I feel better, I can stop taking the antibiotics.”
d. “It is important to finish all the antibiotics prescribed.”
c. “Once I feel better, I can stop taking the antibiotics.”
Rationale: Patients with IE require prolonged antibiotic therapy to fully eradicate the infection and prevent recurrence. Stopping antibiotics prematurely increases the risk of relapse or antibiotic resistance. The other statements reflect appropriate understanding.
Which patient is most likely to develop acute infective endocarditis (IE)?
a. A 55-year-old with a history of rheumatic heart disease
b. A 25-year-old IV drug user with no known valve disease
c. A 70-year-old with a history of prosthetic valve replacement
d. A 45-year-old with mitral valve prolapse and regurgitation.
b. A 25-year-old IV drug user with no known valve disease
Rationale: Acute IE often occurs in individuals with healthy valves, such as IV drug users, due to the rapid introduction of pathogens into the bloodstream. Subacute IE is more common in patients with preexisting valve disease.
A nurse is reviewing the diagnostic criteria for infective endocarditis (IE). Which clinical feature is most indicative of subacute IE?
a. Low-grade fever persisting for weeks
b. Rapid onset of heart failure symptoms
c. Sudden onset of septic emboli
d. Acute confusion and neurological changes
a. Low-grade fever persisting for weeks
Rationale: Subacute IE typically presents with nonspecific symptoms like low-grade fever over a prolonged period, often in patients with preexisting valve disease. Rapid onset and severe symptoms are more characteristic of acute IE.
A nurse suspects prosthetic valve endocarditis (PVE) in a patient. What is the most important question to ask during the health history?
a. “Have you ever been diagnosed with a heart murmur?”
b. “Do you have a history of IV drug use?”
c. “When was your valve replacement surgery performed?”
d. “Have you been exposed to anyone with an infection recently?”
c. “When was your valve replacement surgery performed?”
Rationale: PVE can occur early (within 60 days of surgery) or late (after 60 days). Knowing the timing helps determine the causative pathogen and guide treatment. Other questions are relevant but less critical for diagnosing PVE.
Which clinical manifestation would most likely be seen in a patient with subacute IE?
a. Osler nodes and splenomegaly
b. Acute onset of chest pain and dyspnea
c. High fever and signs of septic shock
d. Sudden neurologic deficits
a. Osler nodes and splenomegaly
Rationale: Subacute IE commonly presents with Osler nodes (painful, raised lesions on fingers/toes) and splenomegaly, reflecting chronic infection. Acute symptoms such as chest pain, septic shock, and neurologic deficits are more consistent with acute IE.
A nurse is caring for a patient with fungal infective endocarditis. Which treatment plan is most appropriate?
a. Long-term oral antibiotics
b. Short-term IV antibiotics followed by oral therapy
c. IV antifungal therapy and possible valve surgery
d. Antipyretics and observation for symptom resolution
c. IV antifungal therapy and possible valve surgery
Rationale: Fungal IE is difficult to treat and often requires aggressive antifungal therapy and valve replacement. Antibiotics alone or observation are insufficient for fungal infections.
Which patient is at the highest risk of developing infective endocarditis (IE)?
a. A patient with mitral valve prolapse without regurgitation
b. A patient undergoing renal dialysis
c. A patient with a history of hypertension
d. A patient with chronic atrial fibrillation
b. A patient undergoing renal dialysis
Rationale: Renal dialysis is a major risk factor for IE due to repeated vascular access, which increases the likelihood of bloodstream infections. Other options have a lower risk for IE.
What is the most common causative organism of infective endocarditis?
a. Staphylococcus aureus
b. Streptococcus viridans
c. Haemophilus influenzae
d. Eikenella corrodens
a. Staphylococcus aureus
Rationale: Staphylococcus aureus is responsible for about 50% of IE cases and is a common cause of both community-acquired and healthcare-associated IE.
A nurse suspects embolization in a patient with IE. Which symptom suggests embolization from a left-sided vegetation?
a. Hemoptysis
b. Sudden onset of dyspnea
c. Acute flank pain
d. Pleuritic chest pain
c. Acute flank pain
Rationale: Embolization from left-sided vegetations can cause infarction in organs such as the kidneys, leading to flank pain. The other symptoms are more indicative of right-sided embolization (e.g., pulmonary embolism).
n a patient with right-sided infective endocarditis, what is the most likely complication?
a. Cerebral embolism
b. Splenic infarction
c. Pulmonary embolism
d. Myocardial infarction
c. Pulmonary embolism
Rationale: Right-sided IE causes vegetations to embolize to the lungs, leading to pulmonary embolism. Left-sided IE is associated with embolization to systemic organs.
Which diagnostic test is most definitive for identifying vegetations in infective endocarditis?
a. Transthoracic echocardiogram (TTE)
b. Transesophageal echocardiogram (TEE)
c. Chest X-ray
d. Blood cultures
b. Transesophageal echocardiogram (TEE)
Rationale: TEE is more sensitive than TTE for detecting vegetations on heart valves, making it the gold standard for diagnosing IE.
A patient with IE is found to have heart block on ECG. What does this indicate?
a. Myocardial invasion
b. Pulmonary embolism
c. Acute ischemic stroke
d. Valvular stenosis
a. Myocardial invasion
Rationale: Invasion of the myocardium by the infection can disrupt electrical conduction pathways, resulting in heart block.
Which statement by a patient with a prosthetic valve indicates a need for further teaching about preventing infective endocarditis?
a. “I will need antibiotics before dental procedures.”
b. “I should report any symptoms of infection, like fever, to my doctor.”
c. “I don’t need to take antibiotics if I’m feeling healthy.”
d. “Good oral hygiene is important to prevent infections.”
c. “I don’t need to take antibiotics if I’m feeling healthy.”
Rationale: Prophylactic antibiotics are required for high-risk patients undergoing certain procedures, regardless of how they feel, to prevent bacteremia and IE.
What is the most appropriate nursing intervention for a patient with IE and signs of systemic embolization?
a. Administer anticoagulants immediately
b. Notify the healthcare provider
c. Prepare the patient for emergency valve replacement surgery
d. Perform a neurological assessment
b. Notify the healthcare provider
Rationale: Systemic embolization is a serious complication requiring immediate medical evaluation. Anticoagulants are not always indicated in IE-related embolization.
Which complication is most associated with left-sided IE?
a. Heart failure
b. Pulmonary embolism
c. Deep vein thrombosis
d. Pleural effusion
a. Heart failure
Rationale: Left-sided IE often damages the heart valves and supporting structures, leading to valve dysfunction and heart failure.
Why are HACEK organisms significant in infective endocarditis?
a. They are the most common cause of IE.
b. They are resistant to all antibiotics.
c. They are associated with IV drug use.
d. They form biofilms that increase resistance to treatment.
d. They form biofilms that increase resistance to treatment.
Rationale: HACEK organisms produce biofilms that protect them from immune defenses and antibiotics, complicating treatment.
*What is the primary reason embolization occurs in infective endocarditis?
a. Increased platelet count
b. Fragility of vegetation
c. Valvular regurgitation
d. High blood pressure
b. Fragility of vegetation
Rationale: Embolization occurs when fragile vegetations made of fibrin, platelets, leukocytes, and microbes dislodge and travel through the bloodstream.
What nursing intervention is most critical for a patient with suspected infective endocarditis?
a. Obtain blood cultures before initiating antibiotics
b. Monitor for signs of venous thrombosis
c. Administer antipyretics for fever
d. Schedule an echocardiogram for diagnosis
a. Obtain blood cultures before initiating antibiotics
Rationale: Blood cultures must be obtained before starting antibiotics to identify the causative organism and guide treatment.
Which patient scenario represents a healthcare-associated infection leading to IE?
a. A patient undergoing chemotherapy develops IE from an infected IV catheter.
b. A patient develops IE 3 months after valve surgery.
c. A patient with poor dental hygiene develops IE.
d. A patient with a history of rheumatic fever develops IE.
a. A patient undergoing chemotherapy develops IE from an infected IV catheter.
Rationale: Healthcare-associated IE commonly results from infections linked to invasive devices like IV catheters.
Which symptom is most indicative of embolization to the brain in IE?
a. Hematuria
b. Shortness of breath
c. Petechiae
d. Confusion
d. Confusion
Rationale: Confusion or other neurological deficits suggest embolization to the brain, leading to an ischemic stroke.
What is the primary purpose of prolonged antibiotic therapy in infective endocarditis?
a. To prevent embolization of vegetation
b. To improve valve function
c. To eradicate organisms protected by biofilms
d. To reduce fever and inflammation
c. To eradicate organisms protected by biofilms
Rationale: Prolonged antibiotic therapy is necessary to penetrate biofilms and completely eliminate the infecting organisms.
Which clinical finding is most specific to infective endocarditis (IE)?
a. Generalized fatigue and malaise
b. Petechiae on the buccal mucosa
c. Osler’s nodes on fingertips
d. Low-grade fever
c. Osler’s nodes on fingertips
Rationale: Osler’s nodes are a hallmark sign of IE, caused by immune complex deposition. Petechiae and fever are common but not specific to IE.
What is the most likely explanation for a new systolic murmur in a patient with IE?
a. Development of mitral valve prolapse
b. Valve damage due to vegetation
c. Increased cardiac output
d. Myocardial infarction
b. Valve damage due to vegetation
Rationale: Vegetations in IE can damage heart valves, leading to new or worsening murmurs, particularly with left-sided valve involvement.
A nurse assesses splinter hemorrhages in a patient with suspected IE. Where should the nurse examine for this finding?
a. Palms of the hands
b. Nail beds
c. Conjunctivae
d. Buccal mucosa
b. Nail beds
Rationale: Splinter hemorrhages appear as black longitudinal streaks under the nail beds, resulting from microemboli.
What is the primary reason older adults with IE may not present with a fever?
a. Their immune system produces fewer cytokines.
b. Vegetations primarily form in the right heart.
c. They have fewer systemic embolizations.
d. Their valves are less likely to be damaged.
a. Their immune system produces fewer cytokines.
Rationale: Older adults or immunocompromised patients may have a diminished febrile response due to reduced immune system activity.
Which finding is consistent with Janeway’s lesions in IE?
a. Painful red spots on the palms
b. Painless flat red spots on the soles
c. Tender purple lesions on the toes
d. Hemorrhagic streaks on the nail beds
b. Painless flat red spots on the soles
Rationale: Janeway’s lesions are painless, flat, red spots typically seen on the palms or soles. They are caused by septic microemboli.
In a patient with IE, which symptom would suggest heart failure as a complication?
a. Bilateral crackles on lung auscultation
b. Petechiae on the conjunctivae
c. Splinter hemorrhages in nail beds
d. Roth’s spots on retinal exam
a. Bilateral crackles on lung auscultation
Rationale: Heart failure, a common complication of IE, often manifests with pulmonary congestion, leading to crackles on auscultation.
Why are murmurs typically absent in tricuspid valve infective endocarditis?
a. Right-sided vegetations rarely cause valve dysfunction.
b. Pulmonary embolism masks the murmur.
c. The tricuspid valve is not commonly affected in IE.
d. Right-sided heart sounds are too faint to detect.
d. Right-sided heart sounds are too faint to detect.
Rationale: Murmurs in tricuspid valve IE are often absent because right-sided heart sounds are less audible compared to left-sided murmurs.
Which combination of criteria confirms a diagnosis of IE according to the Duke Criteria?
a. One major and one minor criterion
b. Two major criteria and one minor criterion
c. Five minor criteria
d. Either b or c
d. Either b or c
Rationale: A diagnosis of IE is made with 2 major criteria and 1 minor criterion, or 5 minor criteria, per the Duke Criteria.
Which laboratory finding supports the diagnosis of acute IE?
a. Normal ESR and CRP levels
b. Mild leukocytosis
c. Negative blood cultures
d. Decreased platelet count
b. Mild leukocytosis
Rationale: Mild leukocytosis is a common finding in acute IE due to the systemic inflammatory response.
Why is echocardiography crucial in the diagnosis of IE?
a. It identifies the microorganism causing the infection.
b. It rules out culture-negative IE.
c. It confirms the presence of vegetations on the valves.
d. It detects changes in C-reactive protein levels.
c. It confirms the presence of vegetations on the valves.
Rationale: Echocardiography (especially transesophageal) is essential for visualizing vegetations, which is a key diagnostic feature of IE.
Which minor criterion in the Duke Criteria is most likely to be documented in a patient with a history of IV drug use?
a. Vascular phenomena
b. Immunologic phenomena
c. Predisposing heart condition or IV drug use
d. Echocardiographic findings
c. Predisposing heart condition or IV drug use
Rationale: A history of IV drug use is a recognized minor criterion for IE, as it increases the risk of infection.
When collecting blood cultures for suspected IE, what is the best approach?
a. Collect three blood cultures over 1 hour from different sites.
b. Draw all cultures from a single venipuncture site.
c. Obtain blood cultures only after starting antibiotics.
d. Collect blood samples every 12 hours.
a. Collect three blood cultures over 1 hour from different sites.
Rationale: This approach ensures adequate detection of bacteremia while reducing the risk of contamination.
A patient with suspected IE has received antibiotics for a skin infection in the past 2 weeks. What diagnostic challenge might this pose?
a. False-positive echocardiographic findings
b. Negative blood cultures despite active infection
c. Decreased C-reactive protein (CRP) levels
d. Absence of leukocytosis
b. Negative blood cultures despite active infection
Rationale: Recent antibiotic use can lead to culture-negative IE, as it may suppress bacterial growth in blood cultures.