Chapter 40 (4)

Question 1

The goals of therapy when prescribing hormone replacement therapy (HRT) include reducing:

Answer 1

Vasomotor symptoms

Question 2

The optimal maximum time frame for HRT or estrogen replacement therapy (ERT) is:

Answer 2

5 years

Question 3

Dosage changes of conjugated equine estrogen (Premarin) are made at _____ intervals.

Answer 3

6 to 8 week

Question 4

The advantage of vaginal estrogen preparations in the treatment of vulvovaginal atrophy and dryness is:

Answer 4

Relief of symptoms without increasing cardiovascular risk

Question 5

Women with an intact uterus should be treated with both estrogen and progestin due to:

Answer 5

Increased risk for endometrial cancer if estrogen alone is used

Question 6

Ongoing monitoring for women on ERT includes:

Answer 6

All of the above

Question 7

Kristine would like to start HRT to treat the significant vasomotor symptoms she is experiencing during menopause. Education for a woman considering hormone replacement would include:

Answer 7

Discussing the advantages and risks of HRT

Question 8

Angela is a black woman who has heard that women of African descent do not need to worry about osteoporosis. What education would you provide Angela about her risk?

Answer 8

Black women are at risk of developing osteoporosis due to their lower calcium intake as a group.

Question 9

Drugs that increase the risk of osteoporosis developing include:

Answer 9

Carbamazepine

Question 10

Selective estrogen receptor modifiers (SERMs) treat osteoporosis by selectively:

Answer 10

Selectively acting on the estrogen receptors in the bone

Question 11

Sallie has been diagnosed with osteoporosis and is asking about the “once a month” pill to treat her condition. How do bisphosphonates treat osteoporosis?

Answer 11

By reducing bone resorption and inhibiting osteoclastic activity

Question 12

Inadequate vitamin D intake can contribute to the development of osteoporosis by:

Answer 12

Increasing calcium absorption from the intestine

Question 13

The drug recommended as primary prevention of osteoporosis in women over age 70 years is:

Answer 13

Alendronate (Fosamax)

Question 14

The drug recommended as primary prevention of osteoporosis in men over age 70 years is:

Answer 14

Alendronate (Fosamax)

Question 15

The ongoing monitoring for patients over age 65 years taking alendronate (Fosamax) or any other bisphosphonate is:

Answer 15

Annual renal function evaluation

Question 16

Bisphosphonate administration education includes:

Answer 16

Requiring sitting erect for at least 30 minutes afterward

Question 17

IV forms of bisphosphonates are used for all the following except:

Answer 17

Persons with advancing renal dysfunction

Question 18

What is the established frequency of repeating DEXA imaging after stating bisphosphonates?

Answer 18

There is no evidence-based time line for monitoring after the first 2 years

Question 19

What is the duration of SERM use for menopausal issues?

Answer 19

The bone health impact allows long-term use

Question 20

Why are SERMS generally not ordered for women early into menopause?

Answer 20

The rapid onset of severe hot flashes can be unbearable.