Chapter 4: Histology Flashcards
histology
study of the structure of tissues
tissue
composed of cells and surrounding extracellular matrix (ECM)
extracellular matrix composition (ECM)
is composed of the substances surrounding the cells in a tissue
ECM has 2 main components: ground substance and protein fibers
4 classes of tissues
epithelial, connective, muscle, and nervous tissue
function of ECM
provides tissue with strength, regulates cell activity, and anchors cells in place
3 types of protein fibers
collagen, elastic, and reticular fibers
collagen fibers
most abundant protein in body; composed of multiple subunits of fibrous protein
- very resistant to tension/pressure (STRONG)
elastic fibers
- composed of the protein “elastin”, that’s surrounded by glycoproteins
- very STRETCHY and does NOT break, returns to original length
reticular fibers
a type of collagen fiber
thinner and shorter than collagen fibers, and they interweave to form a meshwork (reticul- = “netlike”) that supports cells and the ground substance of many tissues.
cell junctions
intercellular connections between the plasma membranes of adjacent cells of tissues
tight junctions
make the space between adjacent cells impermeable to macromolecules (sealed tight)
desmosomes
anchor neighboring cells together to increase the strength of a tissue with respect to mechanical stress
gap junctions
small pores in the plasma membranes of two adjacent cells that allow small substances to pass from the cytosol of one cell to that of another
functions of epithelial tissues
function in protection, immune defenses, secretion, transport, and sensation
what cell junctions does epithelial cells have?
epithelial cells are joined by tight junctions and desmosomes
basement membrane
thin, dense layer of ECM that anchors epithelia to underlying tissues
is Epithelia vascular or avascular?
avascular (no blood vessels)
simple epithelia
only one cell layer
stratified epithelia
have 2 or more cell layers
squamous epithelia
FLAT cell layer(s)
cuboidal epithelia
CUBED cell layer(s)
columnar epithelia
COLUMN shaped (long) cell layer(s)
describe transport across simple epithelia
only 1 thin cell layer, substances are able to cross them rapidly
2 types of transport across epithelia
paracellular transport and transcellular transport
paracellular transport
substances can leak between the cracks of the epithelial cells
transcellular transport
process where substances cross epithelia directly
substance enters cell’s the phospholipid bilayer, diffuses through cytosol, and exits through other cell surface.
list of simple epithelia
simple squamous, simple cuboidal, and simple columnar epithelium
ciliated pseudostratified columnar epithelium
a type of simple epithelium that appears stratified but consists of only a single layer of cells
list of stratified epithelium
stratified squamous (may or may have keratinized layer)
stratified cuboidal and columnar epithelia (both rare in body)
transitional epithelium (found in urinary system)
2 types of glands in the body
exocrine, and endocrine glands
exocrine glands
release their product through a duct to an epithelial surface. Most of their products have local actions
endocrine glands
release their product into the bloodstream
their products can have actions on distant target cells in the body
structure of multicellular glands
vary in shape and complexity