Chapter 4 Flashcards
absorbed
When drugs have entered the bloodstream
antagonism
the diminished or reduced effect of a drug when another drug is present
as a function of
a term expressing correlation. in graphs of functional relationships between two variables, changes in one variable associated with changes in another (drug dose) are represented.
bioavailability
The portion of the original drug dose that reaches its site of action or that reaches a fluid in the body that gives it access to its site of action
control
In research, to be able to account for variables that may affect the results of a study.
Diffusibility
A more diffusible substance is more easily entered into or “receptive” of another
Dissolved
When a drug changes from solid to liquid by mixing it with a liquid.
Distribution
The transport of drugs by the blood to their site(s) of action in the body.
Drug potency
The minimum effective dose of a drug.
Effective dose
The dose at which a given percentage of individuals show a particular effect of a drug
Efficacy
The most intense, or peak, level of a drug effect
Feedback
In this context, in a series of events, what happens in a later event alters events that preceded it.
Freebase
When a substance is separated, or “freed” from its salt base. The separated form of the substance is thus called “freebase”.
Half-life
The amount of time that must pass for the amount of drug in the body to be reduced by half
Interact
When the effects of one drug are modified by the presence of another drug.