chapter 31: medication administration Flashcards

1
Q

Federal Regulations

A

Pure Food and Drug Act
FDA
National Formulary
USP
Medwatch

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2
Q

Sate/ Local Govt

A

adhere to Fed standars
have some say over stuff not covered by Fed standards
regulate alc and tobacco

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3
Q

Health Care Agencies

A

Meet Fed and State policies
Usually stricter though - e.g. automatic stop of narcotics after certain amt of days

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4
Q

Nurse Practice Acts

A

define scope of nurses’ professional functions and responsibilities

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5
Q

Med names

A

3: chemical, generic, and trade/brand name

Capitalize key letters to keep from making a mistake

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6
Q

Pharmacokinetics

A

study of how meds enter the body, reach their site of action, metabolize, and exit body

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7
Q

Absorption

A

med molecules pass into blood from site of med administration

Fast to slow:
on skin
oral
mucous memrane / respiratory airway
subcutaneous
intramuscular
Intravenous

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8
Q

which absorbs faster:
liquids or tablets/capsules?
acidic or alkaline meds?
lipid- or water- soluble?

A

liquids
acidic
lipid

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9
Q

Factors affecting absorption

A

route
ability to dissolve
blood flow to site of admission
body surface area
lipid solubility

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10
Q

Factors affecting distribution

A

Circulation –> good blood flow = fast delivery
Membrane permeability –> e.g. BBB only permeable to fat soluble stuff
Protein binding –> most meds partially bind to albumin - the rest is active

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11
Q

Metabolism of drugs

A

biotransformation occurs thru enzymes that detoxify, break down, and remove active chems

Liver is main one, but lungs, kidney, blood, and intestines do it too

If these organs aren’t working, meds accumulate and become toxic

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12
Q

Excretion

A

through kidneys, liver, bowel, lungs, and exocrine glands

lungs excrete NO, alc, and anesthesia
exocrine glands secrete lipid soluble stuff
Meds that go through digestion reabsorbed in small intestine - slowed emptying increases effects
KIDNEYS ARE MAIN ONE —> stay hydrated

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13
Q

Therapeutic effect

A

expected, predicted physiological response caused by the med

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14
Q

Adverse effects: who’s at risk?

A

young
old
pregnant
multiple meds
overweight
underweight
renal or liver disease

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15
Q

Side effects

A

predictable and often unavoidable adverse effect

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16
Q

Toxic effects

A

develop after taking for long time or if it accumulates

death!

Naloxone is antidote for opioids

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17
Q

Idiosyncratic reaction

A

overreaction, underreaction, or unexpected response to a med

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18
Q

Allergic reactions

A

-body sees med as antigen and so releases antibodies to fight it

Anaphylactic rxns = constriction of bronchiolar muscles, edema of pharynx/larynx, severe wheezing and shortness of breath

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19
Q

Medication interactions

A

synergistic effect = increase effect of each other

e.g. alc has synergistic effect on antihistamines, antidepressants, barbiturates, and narcotic analgesics

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20
Q

Medication tolerance and medication dependance

A

need higher doses to produce same outcome: morphine, nitrates, alc

Dependance is psychological and/or physical
-physical if withdrawal happens

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21
Q

Minimum effective concentration (MEC)

A

minimum amt of med in plasma needed to make effects happen

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22
Q

safe therapeutic range

A

tried to attain this consistently

bt MEC and toxic concentration

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23
Q

Biological half life

A

time it takes for excretion processes to lower serum medication concentration by half

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24
Q

Time intervals to know when administering meds

A
  1. Onset of med action = time to take effect
  2. peak action = time to reach peak
  3. trough = min blood serum level before next dose
  4. duration of action = how long the therapeutic effect is working
  5. plateau = blood serum concentration reached and maintained after repeated fixed doses
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25
Sublingual meds
put under tongue where it dissolves don't ingest don't drink anything til med is completely dissolved
26
Buccal administration
solid med put on inside of cheeks to dissolve don't eat it alternate cheeks with each dose
27
4 typical parenteral routes of administration 6 rarer parenteral routes of administration 2 only for drs
ID = intradermal = just under epidermis Subcutaneous = into tissues just below dermis IM = intramuscular = into muscle IV = intravenous = into the vein Epidural = epidural space via catheter Intrathecal = catheter into subarachnoid space Intraosseous = into bone marrow --> mostly for babies Intraperitoneal = into peritoneal cavity --> chemo, insulin, and antibiotics Intrapleural = into plaural space --> chemo or anti-pleural effusion Intraarterial = into artery --> clot dissolving agents intracardiac and intraaricular (into joint)
28
Topical administration
applly to skin/mucous membrane Transdermal disk/patch has systemic effects -- leave on for 1-7 days 1. direct application of ointment (eyedrops) 2. insertion of medication into body cavity (suppository into rectum) 3. intillatino of fluid into body cavity (ear drops) 4. irrigation of body cavity 5. spraying med -- e.g. into nose
29
Inhalation route
endotracheal, nasal, or oral passages
30
Intraocular route
contact lens with meds on it --> stays in for a week
31
How should non OTC meds be measured in hospital?
pharmacy should measure with oral syringe using metric measurements
32
Solution
mass of solid substance dissolved in known volume of fluid OR fluid mixed with fluid express in g/L or mg/mL or percentages
33
should you be converting between systems?
not really, but if its necessary then i guess its necessary
34
Ratio and proportion method
1:2::4:8 ---> 1 and 8 are "extremes"; 2 and 4 are "means" --> product of extremes = that of means
35
Formula method
(dose ordered / dose on hand) x (amount on hand) = how much to give
36
Dimensional analysis
the fun, multi ratio multiplication thing
37
Ped doses basic safety measure
have most errors -use metric only --> round to neares 0.1, 0.5, or 1 ml -no household measurements -tailor to BMI -hands on and return demonstration -pic based education may be appropriate
38
How to calculate dose for child
-WEIGHT --> avoid converting bt lbs and kgs -IM don't exceed 1 mL for kids or 0.5 mL in babies -Subcutaneous don't exceed 0.5 mL -If less than 1 mL, use syringe with tenths -Use tuberculin syringe if need to be rounded to thousandth -estimate first and then compare -compare amt ordered over 24 hr to recommendations
39
verbal order
order for med given verbally -write it, read it back, get confirmation Indiacte time and name of HCP who gave order -sign it, indicate it was read back, and get HCP to sign it DON'T USE ABBREVIATIONS DURING DOCUMENTATION
40
Standing orders / Routine medication orders
Carried out until HCP cancels it or prescribed number of days passes
41
prn order don'ts
No ranges if vague -maybe ranges if given explicit conditions: e.g. increase mmorphine dosage 50-100% if pain is moderate to severe based on use of pain scale
42
Now vs STAT orders
Now is within 90 mins STAT is as soon as possible --> emergency!
43
Prescriptions
orders taken to outside agencies sometimes, if for controlled substance, have to be written on dif colored prescription pad than other orders
44
Pharmacists job
dispense correct med in proper dosage and amount with accurate label don't really mix stuff except in IV solutions
45
Unit dose
storage system with individually wrapped doses for patients in individual drawer usually only 24 hr supply is kept in drawer --> pharmacist refills at particular time certain amt of prns in drawer controlled substances kept locked up elsewhere
46
Automated Medication Dispensing Systems (AMDS)
Nurse enters security code and maybe finger print Selects patient, med and dose Drawer opens and the med is documented (in med record) and charged to patient Might be used with bar-code medication administration system (BCMA) where you have to scan the patient's bracelet before it'll give you the meds Includes controlled substances
47
Chemo meds
Have to be certified to administer IV chemo meds, but not oral Chemo drugs are SUPER toxic! DNA damage --> cancer, birth defects, immune issues Excreted through urine, stool, vomit, sweat, and saliva --> double flush! Toilets are biohazard
48
Chemo med guidelines
Store in separate, designated place use special gloves hand hygiene before and after don't break the drug don't use same equipment to prep as other drugs single-use PPE clothes or sheets with body fluid should be washed 2x in washing machine by themselves on HOT
49
DON"T LET AP DO ANY OF THIS
FACTS!
50
Medication error
preventable event that may cause inappropriate med use or jeapordize patient safety 1. assess patient's condition and notify HCP 2. report incident (not permanent part of med record) *****report almost errors too
51
Medication reconciliation
Compare med that they're taking with what they should be taking Often necessary when patient has been/is being transferred
52
The seven rights
1. right med 2. right dose 3. right patient 4. right route 5. right time 6. right documentation 7. right indication
53
Comparing label on medication with that in the MAR
First: before removing container from drawer Again: as amount of med ordered is removed from container Last: at patient's bedside before giving it to them
54
YOU CAN"T ADMINISTER MEDS IF YOU DIDN"T PREP THEM
FACTS
55
What syringe to use when preparing oral medication
enteral syringe --> dif color than others and laeled for oral use
56
When to give time critical meds Non time critical?
within 30 mins before or after stated time within 1-2 hrs befor or after
57
Patient rights
To be informed ab care to make decisions ab care to refuse care to be listened to by care givers to recieve info in a way that meets their needs
58
IMP history stuff to know
allergies meds diet history perceptual or coordination issues
59
Nursing Dagnoses related to meds
Impaired health maintenance Lack of Knowledge Nonadherence Adverse Med ineraction Complex med regimen
60
Components of medication order
Patient's full name Date and time order was written med name dosage route time and frequency of administration signature of HCP
61
How often do adverse effects happen in old ppl?
22% of the time! falls, orthostatic hypotension, heart failure, delerium
62
Polypharmacy
use of mult meds, use of potentially inappropriate/unnecessary meds, or use of med that doesn't match diagnosis