Chapter 30: Medications Flashcards
Chemical name of drug
identifies drug’s atomic and molecular structure
Generic Name of drug
assigned by the manufacturer that first develops the drug; derived from the chemical name
Official name
name by which the drug is identified in official publications (typically generic name)
Trade name:
brand name copyrighted by the company that sells the drug
Ways to prepare drugs
- Oral
- Topical
- Parenteral
Oral Drugs
Capsule, pill, tablet, extended
release, elixir, suspension,
syrup
Topical Drugs
Liniment, lotion, ointment,
suppository, transdermal
patch
Parenteral
Injectable
Infusion
implantation
How are drugs classified?
- Classified by effect on body system;
- Chemical composition;
- Clinical indication or
therapeutic action
Two primary classifications of drugs
- Pharmaceutical class
- Therapeutic class
Pharmaceutical class
Refers to the mechanism of action (MOA), physiologic effect (PE), and chemical structure (CS) of the drug
Therapeutic Class
Refers to the clinical indication for the drug or therapeutic action (e.g., analgesic, antibiotic, or antihypertensive).
Pharmacokinetics (Effect of Body on Drug)
- Absorption
- Distribution
- Metabolism
- Excretion
Factors Affecting Absorption of Medications:
- Route of Administration
- Lipid solubility
- pH
- Blood flow
- Local conditions at the site of administration
- Drug dosage
Pharmacodynamics
Pharmacodynamics is the process by which drugs alter cell physiology and affect the body
Drug Receptor interaction
occurs when the drug interacts with one or more cellular structures to alter cell function
Types of Adverse Drug Reactions
Side effects:
Allergic effects: anaphylactic
reaction
Drug tolerance
Toxic effect
Idiosyncratic effect
Drug interactions:
antagonistic and synergistic
effects
Factors Affecting Drug Action
- Developmental considerations
- Weight
- Biologic sex
- Cultural and genetic factors
(ethnopharmacology) - Psychological factors
- Pathology
- Environment
- Timing of administration
Therapeutic Range
Concentration of drug in the blood serum that produces the desired effect without causing toxicity
Peak Level
Highest Plasma Concentration of a Drug
Trough Level
The point when the drug is at its lowest concentration, indicating the rate of elimination
Half Life
Amount of time it take for 50% of blood concentration of a drug to be eliminated from the body
Types of Medication Orders
Standing order (routine order)
PRN order
Single or one time order
Stat order
Standing order (routine order)
Carried out until cancelled by another order