Chapter 3: Neuroscience and Behavior 3.1-3.3 Flashcards

1
Q

Neurons

A

Cells in the nervous system that communicate with each other to perform information processing tasks

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2
Q

Cell body

A

Aka the soma is the largest component of the neuron that coordinates the information-processing tasks like protein synthesis, cell production, and metabolism, and keeps the cell alive; enclosed by a porous cell membrane that allows some molecules to flow into and out of the cell

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3
Q

Nucleus

A

Contained in the cell body and houses chromosomes that contain your DNA

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4
Q

What are the two types of specialized extensions of the cell membrane?

A

Dendrites and axons

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5
Q

Dendrites

A

Greek for “tree,” receive information from other neurons and relay it to the cell body

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6
Q

Axon

A

Carries information to other neurons, muscles, or glands; can be very long

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7
Q

What covers the axon (in many neurons)?

A

Myelin sheath, an insulating layer of fatty material composed of glial cells (Greek for “glue”)

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8
Q

Glial cells

A

Support cells found in the nervous system that serve different functions like digesting parts of dead neurons, providing physical and nutritional support for neurons, and forming myelin that insulates the axon and allows it to carry information more efficiently

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9
Q

Demyelinating diseases

A

E.g. multiple sclerosis, cause the myelin sheath to deteriorate, slowing the communication from one neuron to another which lead to problems like loss of feeling in limbs, partial blindness, difficulties in coordinated movement and cognition

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10
Q

Synapse

A

Junction or region between the axon of one neuron and the dendrites or cell body of another

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11
Q

What are the three major types of neurons?

A

Sensory, motor, and interneurons

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12
Q

Sensory neurons

A

Receive information from the external world and convey this information to the brain via spinal cord; have specialized endings on their dendrites that receive signals for light, sound, touch, taste, and smell

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13
Q

Motor neurons

A

Carry signals from the spinal cord to the muscles to produce movement, often have long axons that reach to muscles at our extremeties

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14
Q

Interneurons

A

Connect sensory neurons, motor neurons, or other interneurons; work together in small circuits to perform tasks like identifying the location of a sensory signal and recognizing a familiar face

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15
Q

Purkinje cells

A

Type of interneuron that carries information from the cerebellum to the rest of the brain and the spinal cord; have dense elaborate dendrites that resemble bushes

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16
Q

Pyramidal cells

A

Found in the cerebral cortex, have a triangular cell body and a single, long dendrite among many smaller dendrites

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17
Q

Bipolar cells

A

Type of sensory neuron found in the retinas of the eye, have a single axon and a single dendrite

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18
Q

What are the two stages of electrochemical action in neurons?

A

Conduction and transmission

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19
Q

Conduction

A

Movement of an electric signal within neurons, from the dendrites to the cell body, then throughout the axon

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20
Q

Transmission

A

Movement of a signal from one neuron to another as a result of chemical signalling across the synapse

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21
Q

Resting potential

A

The difference in electric charge due to varying concentrations of ions between the inside and outside of a neuron’s cell membrane

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22
Q

When is a neuron in resting state?

A

Inside the neuron’s cell membrane, there is a high concentration of positively charged potassium ions (K+) and larger negatively charged protein ions (A-) compared to outside it. Outside the neuron’s cell membrane, there is a high concentration of positively charged sodium ions (Na+) and negatively charged chloride (Cl-). A- ions are larger and carry a stronger charge than the others so the inside of the cell membrane is negatively charged at -70 millivolts relative to the outside during resting potential.

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23
Q

Action potential

A

Electric signal that is conducted along the length of a neuron’s axon to a synapse

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24
Q

Explain “the action potential is all or none”

A

Electric stimulation or shock below the threshold fails to produce an action potential while electric stimulation at or above the threshold always produces the action potential at the same magnitude (value is above zero at +40 millivolts)

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25
Q

How does the total charge inside the axon change from negative to positive?

A

During resting potential, voltage-gated channels for Na+ ions are closed. When the voltage across the cell body membrane reaches the threshold, sodium-specific channels on the nearby axons open up and Na+ ions rush out into the cell instantaneously, changing the total charge in the axon from negative to positive in less than a millisecond.

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26
Q

What two events restore the negative charge of the resting potential?

A

(1) Na+ channels are inactivated or in a refractory period for several milliseconds, stopping the flow of Na+ ions (2) Channels specific to K+ ions open, allowing K+ ions inside the cells to exit, then the channels close

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27
Q

Refractory period

A

The time following an action potential during which a new action potential cannot be initiated; limits the number of times a neuron can fire and keeps the action potential from travelling back to the cell body

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28
Q

Explain the domino effect of action potential across the neuron

A

When the first voltage channels open, Na+ ions spread and increase the electrical charge down the inside of the axon. When the voltage around adjacent voltage channels reaches the threshold, those open and let in more Na+ ions that spread further. The influx of Na+ ions triggers the nearby channels to open (each reaching +40) and the process repeats down the entire axon.

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29
Q

What is the effect of the myelin sheath on the action potential?

A

Conduction of the action potential is greatly increased by the presence of a myelin sheath around the axon; prevents electric current from leaking out of it

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30
Q

What is the structure of the myelin sheath?

A

Doesn’t cover the entire axon; has break points called nodes of Ranvier between clumps

31
Q

Saltatory conduction

A

Electric current jumps quickly from node to node where it slows down, which then helps speed the flow of information down the axon

32
Q

Terminal buttons

A

Knoblike structures at the end of an axon which are each filled with tiny vesicles or bags that contain neurotransmitters

33
Q

Neurotransmitters

A

Chemicals that transmit information across the synapse to a receiving neuron’s dendrites

34
Q

Receptors

A

Found in the dendrites of the receiving neuron; parts of the cell membrane that receive neurotransmitters and either initiate or prevent a new electric signal

35
Q

What are presynaptic and postsynaptic neurons?

A

The sending neuron is presynaptic and the receiving neuron is the postsynaptic neuron

36
Q

Synaptic transmission

A

The sending of neurotransmitters from the presynaptic neuron down the axon to the terminal buttons where they are released from vesicles into the synapse, then received by binding to receptor sites on the nearby dendrite of the postsynaptic neuron

37
Q

What tells dendrites which of the neurotransmitters flooding into the synapse to receive?

A

(1) Neurons tend to form pathways in the brain that are characterized by specific neurotransmitters (2) Like a lock-and-key system, only some neurotransmitters bind to specific receptor sites on a dendrite

38
Q

What three processes make neurotransmitters leave the synapse?

A

Reuptake, Enzyme deactivation, Diffusion

39
Q

Reuptake

A

Neurotransmitters are absorbed by the terminal buttons of the presynaptic neuron’s axon or by neighbouring glial cells

40
Q

Enzyme deactivation

A

Specific enzymes break down specific neurotransmitters

41
Q

Diffusion

A

Neurotransmitters drift out of the synapse and can no longer reach receptors

42
Q

How do autoreceptors stop the release of more neurotransmitters?

A

Neurotransmitters can bind to receptor sites on the presynaptic neuron. These autoreceptors can detect how much of a neurotransmitter has been released and stop the release of more.

43
Q

What are some of the most common neurotransmitters in the nervous system?

A

Acetylcholine (ACh), Dopamine, Glutamate, GABA (gamma-aminobutyric acid), Norepinephrine and Serotonin, Endorphine

44
Q

Acetylcholine (ACh)

A

Involved in voluntary motor control, regulation of attention, learning, sleeping, dreaming, and memory; associated with Alzheimer’s disease where there is deterioration of ACh-producing neurons

45
Q

Dopamine

A

Regulates motor behaviour and emotional arousal, plays roles in basic motivated behaviors like seeking pleasures (e.g. drug addiction) or actions with rewards; high levels are linked to schizophrenia while low levels are linked to Parkinson’s disease

46
Q

Glutamate

A

Major excitatory neurotransmitter, meaning it enhances the transmission of information between neurons

47
Q

GABA (gamma-aminobutyric acid)

A

Primary inhibitory neurotransmitter in the brain, meaning it prevents the firing of neurons

48
Q

What can cause seizures?

A

Too much glutamate or too little GABA make neurons overactive, causing seizures

49
Q

Norepinephrine and Serotonin

A

Influence mood and arousal; low levels of each are linked to mood disorders

50
Q

Norepinephrine

A

Involved in states of vigilance or a heightened awareness of dangers in the environment

51
Q

Serotonin

A

Involved in the regulation of sleep and wakefulness, eating, and agressive behavior

52
Q

Endorphine

A

Chemical that acts within the pain pathways and emotion centers of the brain; dulls the experience of pain and elevates moods; causes the “runner’s high”

53
Q

Agonists

A

Drugs that increase the action of a neurotransmitter

54
Q

Antagonists

A

Drugs that diminish the function of a neurotransmitter

55
Q

Examples of agonist drugs

A

Clondine bind to autoreceptors and block their inhibitory effect, Levodopa or L-dopa increase the production of neurotransmitters (converted to dopamine which medicates Parkinson’s), Amphetamines increase the release of neurotransmitters, Prozac blocks the reuptake of neurotransmitters, Nicotine binds to postsynaptic receptor sites and activates them

56
Q

Examples of antagonist drugs

A

Caffeine activates autoreceptors so they inhibit release of neurotransmitters, AMPT block production of neurotransmitters, Botullinium toxin block the release of neurotransmitters, Naloxone bind to receptor sites and block neurotransmitters

57
Q

Selective serotonin reuptake inhibitors (SSRIs)

A

Drugs that block the reuptake of neurotransmitter serotonin to treat clinical depression e.g. Prozac

58
Q

Beta blockers

A

Obstruct receptor sites in the heart for norepinephrine, a neurotransmitter that increases one’s heartbeat e.g. propranalol

59
Q

Nerves

A

Bundles of axons and the glial cells that support them

60
Q

Nervous system

A

An interacting network of neurons that conveys electrochemical information throughout the body

61
Q

What are the two major divisions of the nervous system?

A

Central nervous system (CNS) and the peripheral nervous system (PNS)

62
Q

Central nervous system

A

Composed of the brain and spinal chord; receives sensory information from the external world, processes and coordinates this, and sends commands to the skeletal and muscular systems for action

63
Q

Brain and spinal chord

A

Brain contains structures that support the most complex perceptual, motor, emotional, and cognitive functions of the nervous system; Spinal chord are nerves that process sensory information and relay commands to the body connected to it

64
Q

Peripheral nervous system

A

Connects the central nervous system to the body’s organs and muscles

65
Q

What are the two major subdivisions of the peripheral nervous system?

A

Autonomic and somatic

66
Q

Somatic nervous system

A

Set of nerves that conveys information between voluntary muscles and the central nervous system

67
Q

Autonomic nervous system

A

Set of nerves that carries involuntary and automatic commands that control blood vessels, body organs, and glands

68
Q

What are the two major subdivisions of the ANS?

A

Sympathetic and parasympathetic nervous systems

69
Q

Sympathetic nervous system

A

Set of nerves that prepares the body for action in challenging or threatening situations

70
Q

What happens when your sympathetic nervous system kicks into action?

A

Dilates pupils, increases heart rate and respiration to pump more oxygen into muscles, diverts blood flow to brain and muscles, activates sweat glands to cool your body, inhibits salivation and bowel movements to conserve energy, suppresses body’s immune responses and responses to pain and injury

71
Q

Parasympathetic nervous system

A

Helps the body return to a normal resting state and reverses the effects of the sympathetic nervous system e.g. constricts pupils and diverts blood flow to digestive system

72
Q

Spinal reflexes

A

Simple pathways in the nervous system that rapidly generate muscle contraction

73
Q

Reflex arc

A

Neural pathway that controls relflex actions