Chapter 3 Flashcards
Glial cells
Support neurons and neuronal functioning, enhances learning and memory, removes waste, creates blood-brain barrier and myelin sheath, responds to injury
Astrocytes
make up brain blood barrier
Oligodendrocytes
make up the myelin shealth in some axons
Synapse
gap between neurons where info is transmitted
synaptic vessicles
contain neurotransmitters
Dendrites
receive information
Axon
send information to other neurons
Axon terminals
contain synaptic vesicles which release neurotransmitters into the synapse
Soma
cell body, manufactures new proteins/cell components, contains nuclei
myelin sheath
insulates axon and increases speed of electrical transmission
nodes of ranvier
gaps in the myelin sheath
Explain the process of an action potential
when a neuron is stimulated it begins to depolarize due to potassium and sodium diffusing across the membrane. Once membrane potential reaches threshold( -55mV), the neuron fires an action potential. The neuron then repolarizes in order to return to its resting state, but in this process it overshoots and enters a brief period of hyperpolarization before then returning to resting potential.
resting potential
neuron’s resting membrane voltage when it is not firing (typically -70mV)
threshold
The minimum cell membrane voltage to trigger depolarization/ an action potential (-55mV)
absolute refractory period
depolarization/repolarization, cell can’t generate another action potential at this point
relative refractory period
hyperpolarization, action potential can be generated at this time given a large enough stimulus
hyperpolarization
relative refractory period
All or none law
cell either depolarizes or it doesn’t, as soon as cell membrane voltage hits -55mV, it sends the same electrical impluse no matter the strength of the stimulus. The strength of the stimulus is determined by the number of action potentials generated.
neurotransmitters
chemicals that carry messages across the synapse to either excite or inhibit other neurons firing(2 types; excitatory and inhibitory)
Five stages of chemical communication
synthesis, storage, release, binding, deactivation (broken down or reuptake)
graded potentials
excitatory postsynaptic potential (EPSP); postsynaptic depolarization, postsynaptic neuron more likely to fire
Inhibitory postsynaptic potential (IPSP); postsynaptic hyperpolarization, postsynaptic neuron less likely to fire
glutamate
main excitatory NT, sensory and learning
drugs- alcohol and sensory enhancers
GABA
main inhibitory NT
alcohol and anti-anxiety
Norepinephrine
cortex arousal
drugs- amphetamine and methamphetamine
Acetylcholine
cortex arousal, selective attention, memory, muscle contradiction
drugs- nicotine, memory enhancers, botox
Dopamine
motor function and pleasure/reward
drugs- L-dopa(treats Parkinsons), antipsychotics
Serotonin
Mood regulation, aggression, sleep-wake cycles, temperature
drugs- SSRI anti-depressants
Endorphins
Pain killers
drugs- codeine, morphine, heroin
Anandamide
Pain killers, increase appetite
drugs- Tetrahydrocannabinol (THC)
Psychoactive drugs
impact the nervous system
agonist
when a drug enhances activity at the receptor site(either binds to receptor site or blocks re-uptake of NTs)
antagonist
when a drug reduces activity at the receptor site
Neural plasticity
The ability of neurons to change over time. 3 areas:
plasticity over development
plasticity and learning
plasticity following injury and/or degeneration
neural plasticity and development
growth (of dendrites and axons), synaptogenesis (formation of new synapses), pruning (destroying certain neurons to remove pathways that aren’t useful), myelination
neural plasticity and learning
synaptogenesis, potentiation(changing of activation and structure of neurons), structural plasticity (nerons change their shape from standard condition to an enriched condition)
neural plasticity, injury, and degeneration
neurogenesis (formation of new neurons) happens in brain, doctors can inject stem cells (undifferentiated cells that can develop into any kind of cell)
The brain-behaviour network
how different regions of the brain are responsible for different behaviours
cerebral cortex
outer grey matter of the cerebrum