Chapter 29/30 Flashcards
Adverse reactions to antibacterials
Allergic mild:pruritis severe: anaphylaxis Superinfection: normal flora is destroyed (2nd day) Organ toxicity
Narrow spectrum antibiotics
peniccillin/erythromycin
Broad spectrum antibiotics
tetracycline/cephalosporins
Penicillin
Beta Lactam antibiotic
-Inhibits cell wall synthesis
Broad spectrum penicillins
treat gram +/-
penicillinase resistant penicillins
used to treat penicillinase producing S. aureus
Extended spectrum penicillins
broad spectrum
beta lactamase inhibitors
inhibits bacterial beta lactamase enzyme
Cephalosporins
generation 1-4
high doses increase risk of bleeding
Erythromycin
Macrolide- inhibits protein synthesis
Broad spectrum
mostly gram +, some -
bacteriostatic/bacteriocidal
side effects of erythromycin
gi distress, tinnitis, superinfection, toxicity
Lincosamides
inhibits protein synthesis
-fights gram +
static/cidal
Vancomycin
inhibits cell wall synthesis
-fights gram +
cidal
Ketolides
block protein bacterial synthesis
-used to treat acquired pneumonia
Tetracyclines
inhibits protein synthesis
broad spectrum +/-