Chapter 27: Psychiatric and Related Disorders Flashcards

1
Q

schizophrenic brain

A
  • lighter
  • larger ventricles
  • less OFC
  • altered neurons in dlPFC and hippocampus
  • reduced GABA
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2
Q

changes in depression

A
  • more cortisol
  • less overall cerebral activity
  • less cingulate, dlPFC, vmPFC and amygdala
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3
Q

changes in bipolar

A
  • less temporal and cerebellum

- neurodegenerative aspect

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4
Q

changes in anxiety disorders

A
  • ACC, mPFC, OFC and hippocampus
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5
Q

changes in PTSD

A
  • less dlPFC
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6
Q

stroke consequences

A
  • 25 to 50% poststroke depression

- 25% poststroke generalized anxiety

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7
Q

Huntington’s disease onset and changes

A
  • between 30 and 50 years
  • cortical thinning
  • basal ganglia atrophy
  • dopamine hyperacticity
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8
Q

coprolalia

A
  • obscene speech in Tourette’s syndrome
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9
Q

Tourette’s syndrome

A
  • subcortical, most likely basal ganglia
  • abnormal frontoparietal circuit
  • RH more affected
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10
Q

postencephalitic Parkinson’s diseas

A
  • either sleeping sickness

- or druginduced

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11
Q

psychological symptoms of Parkinson’s

A
  • decreased feeling, libido, motive, attention
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12
Q

five things about Alzheimer’s disease

A
  • most common form of dementia
  • neuritic plaques from tau protein in cortex
  • made up of amyloid and degenerative cellular fragments
  • paired helical filaments = neurofirillary tangles in cortex and hippocampus
  • shrinkage of cortex and limbic system
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